The Indonesian Biomedical Journal
Vol 10, No 2 (2018)

Anthropometry-based Body Fat Percentage Predicts High hs-CRP in Chronic Kidney Disease Patients

Mochammad Thaha (Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga, Jl. Mayjen Prof. Dr. Moestopo 47, Surabaya)
Maulana Antiyan Empitu (Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Airlangga, Jl. Mayjen Prof. Dr. Moestopo 47, Surabaya)
Ika Nindya Kadariswantiningsih (Department of Medical Microbiology, Faculty of Medicine, Universitas Airlangga, Jl. Mayjen Prof. Dr. Moestopo 47, Surabaya)
Cahyo Wibisono Nugroho (Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga, Jl. Mayjen Prof. Dr. Moestopo 47, Surabaya)
Nurina Hasanatuludhhiyah (Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Airlangga, Jl. Mayjen Prof. Dr. Moestopo 47, Surabaya)
Haerani Rasyid (Department of Internal Medicine, Faculty of Medicine, Universitas Hasanudin, Jl. Perintis Kemerdekaan Km. 10, Makassar)
Zaky El Hakim (Medical Science Program, Faculty of Medicine, Universitas Airlangga, Jl. Mayjen Prof. Dr. Moestopo 47, Surabaya)
Maulana Muhtadin Suryansyah (Medical Science Program, Faculty of Medicine, Universitas Airlangga, Jl. Mayjen Prof. Dr. Moestopo 47, Surabaya)
Rieza Rizqi Alda (Medical Science Program, Faculty of Medicine, Universitas Airlangga, Jl. Mayjen Prof. Dr. Moestopo 47, Surabaya)
Mohammad Yusuf Alsagaff (Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Airlangga, Jl. Mayjen Prof. Dr. Moestopo 47, Surabaya)
Mochammad Amin (Institute of Tropical Disease, Universitas Airlangga, Jl. Mulyorejo, Surabaya)
Djoko Santoso (Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga, Jl. Mayjen Prof. Dr. Moestopo 47, Surabaya)
Yusuke Suzuki (Department of Nephrology, Juntendo University Faculty of Medicine, 2-1-1 Hongo Bunkyo-ku, Tokyo)



Article Info

Publish Date
02 Aug 2018

Abstract

BACKGROUND: Obesity is an important cardiovascular risk factor and associated with low grade inflammation in chronic kidney disease (CKD) patients. This study aims to assess the association between body fat with serum high sensitivity C-reactive protein (hs-CRP) level in CKD patients.METHODS: A cross-sectional study was performed in 71 CKD patients. Anthropometric measurements included body weight, height, body mass index (BMI), body fat percentage (BFP), skinfold thickness (SKF) of triceps and biceps were performed by trained physician. BFP was calculated using Kwok’s Formula and hs-CRP was measured by Particle enhanced Turbidimetry.RESULTS: The averaged BMI of our subjects was 25.8±4.4. There was no significant difference in BMI between pre-dialysis and hemodialysis CKD patients. Positive correlation was found between BFP and hs-CRP (r=0.266; p<0.05), while there was no significant correlation between BMI and hs-CRP.CONCLUSION: Body fat percentage was associated with hs-CRP. Hence, it will be more beneficial to assess nutritional status in CKD using BFP rather than BMI alone since it was demonstrated to correlate with hs-CRP in our studyKEYWORDS: CKD, obesity, inflammation, body fat, hs-CRP

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