Padjadjaran Journal of Dentistry
Vol 20, No 1 (2008): March 2008

Adverse effects of fluoride towards thyroid hormone metabolism

Enggar Abdullah Idris MZ (Universitas Padjadjaran)
Rosiliwati Wihardja (Universitas Padjadjaran)

Article Info

Publish Date
31 Mar 2008

Abstract

An easily ionized fluoride compound like Sodium Fluoride (NaF) has been used thus far as a dental caries prevention substance. However, fluoride ions also have a negative effect because it is very toxic. Several types of research on the effect of fluoride on guinea pigs and human beings indicate the presence synthesis obstruction of T3 and T4 that causes declined production, known as hypothyroidism. Hypothyroidism condition may obstruct tissue growth process and metabolism so as to impact various body organ systems. Preventive efforts against hypothyroidism caused by fluoride include avoiding diffusible fluoride compound intake, like NaF, in a long run systemic use, whereas efforts to overcome fluoride intoxication include consuming food that is rich in calcium, vitamin D, and antioxidant.

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Journal Info
Padjadjaran Journal of Dentistry
Website

Abbrev

PJD

Publisher

Universitas Padjadjaran

Subject

Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Description

Padjadjaran Journal of Dentistry or known as PJD, is an English-language scientific periodicals published by the Faculty of Dentistry Universitas Padjadjaran thrice a year on every March, July and November. The submission process of manuscript is open throughout the year. All submitted manuscripts ...