JURNAL ILMU KEFARMASIAN INDONESIA
Vol 3 No 2 (2005): JIFI

Pengaruh Iradiasi Sinar Gamma dan Konsentrasi Kitosan terhadap Pembentukan Hidrogel Polivinil Alkohol-Kitosan

Zuhelmi Aziz (Universitas Pancasila)
Gatot Trimulyadi (Patir Batan)
Trivena Fithriany A (Universitas Pancasila)



Article Info

Publish Date
29 Sep 2005

Abstract

Chitosan is one of the product from the shrimp disposal. Its medicinal and pharmaceutics application are now developed by pharmaceutical industries, i.e as bioplastics and hydrogel. A research about the effect of gamma radiation and chitosan as a raw material for production of polyvinilalcohol has been carried out. PVA-chitosan hydrogel was made from a mixture of composition of 80% PVA in 10% solution and 20% of chitosan in 0, 1, 2 ,and 3% solution respectively. The mixture was heated in oven at 80°C for two hours and then irradiated with 0, 15, 25, and 35 kGy gamma radiation. The physical characteristic of the gel was determined, e.g. colour, swelling degree and gel fraction. The colour of hydrogel more yellow darker to raising of chitosan concentration and radiation dosage. Swelling degree PVA-chitosan hydrogel increased meanwhile chitosan concentration and radiation dosage decreased. In absolute ethanol medium (96%) PVA-chitosan hydrogel was deswelling. The swelling degree PVAchitosan hydrogel decreased with increased gel fraction.

Copyrights © 2005






Journal Info

Abbrev

jifi

Publisher

Subject

Medicine & Pharmacology

Description

Jurnal Ilmu Kefarmasian Indonesia memuat tulisan ilmiah baik berupa naskah hasil penelitian maupun naskah konsep di bidang Kefarmasian. Diterbitkan setiap 2 (dua) kali dalam setahun yaitu pada bulan April dan ...