Cervical cancer is a significant health problem for women around the world. Every year no less than 15,000 cases of cervical cancer occur in Indonesia and about 20 of the 40 cases died each day (Deherba, 2012). This study to determine the effect of knowledge about the early detection of cervical cancer through the IVA inKarawang regency. Quasi-experimental research design with two sample hypothesis test calculations on the proportion of ? 0.05 and ? 80% earned 35 PUS of each group. The results of this study in the treatment group gained an average of knowledge was 77.9 with a standard deviation 17.19, while in the comparison group gained an average of 45 with the knowledge standard deviation is 15.17.Statistical test results obtained p <0.001, which means that at 5% confidence level there is the influence of health education on knowledge in the early detection of cervical cancer by IVA. The proportion of IVA behavior differed significantly between the control group to the treatment group (p <0.001). Continuous medical education needed by the public to gain knowledge so that foster interest and motivation for the early detection with a medical examination.
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