Indonesian Journal of Cancer Chemoprevention
Vol 7, No 2 (2016)

Effect of Propolis Extract to Heal The Burns in New Zealand Rabbit

Maria Hilaria (Study Program of Pharmacy Health Polytechnic of Kupang)
Elisma Elisma (Study Program of Pharmacy Health Polytechnic of Kupang)
Adrianus L. Uhe (Study Program of Pharmacy Health Polytechnic of Kupang)



Article Info

Publish Date
30 Jun 2016

Abstract

Propolis contains arginine (amino acids), ferulic acid (a derivative compound cinnamic which promotes the formation of collagen), flavonoids (phenolic compounds), and other compounds that can prevent the growth of bacteria, virus, and fungi. The purpose of this study was to measure the most concentration of propolis extracts that effective to heal burns of New Zealand rabbit's.  This was an experimental study with the post-test only control group design. As many as 15 male white rabbits were divided into 5 groups which treated by  propolis extract  with concentration of 50%, 75%, 100%, positive control by bioplacenton and negative control with propylene glycol. The macroscopic observation was done with detached necrosis tissue and the growth of collagen tissue as the parameter. Data were analyzed by using the one-way ANOVA and continued by the SNK test. The results of this study indicated that the propolis extracted have potency on healing burn wound with the significance of 0.00 (p≤0,05). In the concentration of 100%, extract of propolis has  potency on healing burn wound that proportionates with bioplacenton with the significance value of 1.000 (p≥0,05). It is concluded that by increasing dose, the healing time of burn wound will be shortened.Keywords : Propolis, healing burns, rabbit

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Journal Info

Abbrev

ijcc

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Description

Indonesian Journal of Cancer Chemoprevention (IJCC) is an open access, peer-reviewed, triannual journal devoted to publishing articles on Cancer Chemoprevention including Experimental and Clinical Pharmacology, especially concerning Anti-Oxidants, Anti-Aging, Anti-Inflammation, Anti-Angiogenesis, ...