Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)
Vol 6, No 1 (2019)

Formulasi Sediaan Krim Pelembab Ekstrak Air Buah Pepaya (Carica Papaya L.)

Ningsih, Kadek Sri Utami (Unknown)
Darsono, Farida Lanawati (Unknown)
Wijaya, Sumi (Unknown)



Article Info

Publish Date
23 Apr 2019

Abstract

Sucrose in papaya fruit was used as a moisturizer because it has worked as humectants, which reduce water evaporation on the surface of the skin. The purpose of this research was to determine the effect of the increasing concentrations of water extract of papaya fruit to evaluate its physical quality, effectiveness, safety, acceptability, and stability of the moisturizing cream water extract of papaya (Carica papaya L.). In this study, it used 3 formulas containing the extract of papaya fruit at concentration of 10% (formula 1), 20% (formula 2), 30% (formula 3), also blank containing base only, and base without extract and without moisturizing agent. The physical quality tests include organoleptic, pH, viscosity test, emulsion type test, dispersive power test, homogeneity, water washed power and adhesion test. The effectiveness of mouisturizer effect on the skin was tested with in vitro method: Sorption Desorption Test. Savety testing include irritation test and acceptability test. The data was analyzed using oneway ANOVA then continued with post hoc Tukey. The results showed that the increasing concentrations of the extract provides significant effect on efectivity, wherein the greater the concentration of water extract of papaya fruit (Carica papaya L.) were added, then the higher the ability to moisturize the skin and produce of moisturizer cream with pH test 6.04, viscosity 159710 cps, dispersive power 3.63 cm, water washed power 13.48 ml, adhesion 6005 second, and moisturizer cream stable during storage. The best formula is the formula 3 with a concentration extract of 30%.

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Journal Info

Abbrev

JFST

Publisher

Subject

Medicine & Pharmacology

Description

Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) is published twice a year, containing research articles, review, and short communication in pharmacy science field, including medicinal chemistry, analytical chemistry, biologjcal pharmacy, pharmaceutical sciences and ...