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Berkala Ilmiah Kedokteran Duta Wacana
Published by Universitas Kristen Duta Wacana
ISSN : 24609684     EISSN : 24768863     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Berkala Ilmiah Kedokteran Duta Wacana is a Scientific Journal to publish medical research articles, and other scientific medical articles from Medical Faculty of Duta Wacana Christian University academic community and also receive articles from other resources with appropriate and related topics. The policies taken for the largest composition of articles are the results of research, but can also receive scientific articles in the form of literature review and case reports. To maintain the quality of writing, Berkala Ilmiah Kedokteran Duta Wacana also cooperate with other Medical Education Institutions, especially in the recruitment of reviewer partner to conduct a "review" of all incoming articles. Funding for publication is entirely sourced from the Faculty of Medicine and also from Duta Wacana Christian University.
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Articles 8 Documents
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Search results for , issue "Vol 5, No 2 (2020): BERKALA ILMIAH KEDOKTERAN DUTA WACANA" : 8 Documents clear
THE RELATIONSHIP OF CERVICAL VERTEBRAL MATURATION (CVM) STAGE AND ANTEROPOSTERIOR FACIAL DIMENSIONS IN INDONESIAN POPULATION MAHINDRA AWWALUDIN ROMDLON; Setiadi W Logamarta; Yulia Anggraeni
Berkala Ilmiah Kedokteran Duta Wacana Vol 5, No 2 (2020): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v5i2.179

Abstract

Background: Growth and development are two different but interrelated and difficult to separate factors. The growth spurt in boys is different from girls. Facial growth is closely related to overall body growth, one of which is the growth of the cervical vertebrae. Objective: The objective of this study was to determine the anteroposterior dimensions of the face based on the maturation levels of cervical vertebrae in 12-14 years old children. Method: Quantitative research using an analytic observational method with a cross-sectional approach was conducted on 21 boys and 21 girls. Measurement of anteroposterior facial length (S-A' and PTM-A) and assessment of cervical vertebral bone maturation level using the Hassel and Farman method. Results: Independent t-test results showed that there was a significant difference (p
APPROPRIATE LABORATORY AND IMAGING APPROACH FOR EARLY DIAGNOSIS IN HOSPITAL SETTING Teguh Kristian Perdamaian
Berkala Ilmiah Kedokteran Duta Wacana Vol 5, No 2 (2020): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v5i2.240

Abstract

The main objective of global health is to reduce preventable death equally throughout the world. One important strategy is primary prevention through health promotion and early detection. Early diagnosis is defined as several methods to determine in patients the nature of a disease or disorder at its early stage of progression. In a referral health system, such as Indonesia, early diagnosis could be implemented both in primary care and secondary or tertiary referral hospital. Primary care centres screens fatal diseases, such as cancer and cardiovascular risk factors, mostly in asymptomatic patients with identified risk of having the diseases. Accordingly, the early detection programme has been designed for large population in a community setting. It is uncommon for hospitals in Indonesia applying primary prevention where most of the patients are referred with at least a couple of differential diagnoses. Subsequently, early diagnosis in hospital setting would be defined either as accelerating the diagnosis confirmation or detecting any uncommon findings on patients with atypical presentation. In some situation, early detection of life-threatening condition at hospital would prolong or even prevent death. Aside from accurate history taking and comprehensive physical examination, advance laboratory procedure and imaging might assist in early detection at hospital setting. This time, our issue presents case reports on the benefit of early detection in the management of rare disease, anaemia, and COVID-19 pandemic among patients without symptoms or with atypical presentation. In developed countries, most of known congenital diseases were screened prenatally or immediately after delivery. The most common practice in Indonesia is a regular prenatal ultrasound and through physical examination of the baby in their first week. However, this approach would still miss many rare diseases with delayed presentation such as Legg-Calve-Perthes Diseases (LCPD). Pradyana and Astuti1 discussed a paediatric case of LCPD highlighting the difficulty in diagnosis confirmation on a limp gait symptom. Serial imaging not only important in case follow-up, but also to detect newly existing abnormalities which verify the presence of LCPD. Iron deficiency anaemia (IDA) primarily affects women and children in Indonesia. Currently, school-based screening of haemoglobin in teenage girls could prevent the sequalae of IDA through iron supplementation. Early detection in anaemia would determine the presence of IDA before the declined haemoglobin. Recently, international investigators discovered novel biomarker to detect the presence of IDA in asymptomatic patients. Fenty described the potential of using reticulocyte haemoglobin equivalent (Ret-He) to characterize IDA amongst asymptomatic patients in hospital settings.2 This approach would be beneficial for screening purpose in high-risk population, both in community and hospital setting. During COVID-19 pandemic, early diagnosis is a necessity to reduce the infection rate with early quarantine. However, challenging situation might come in patients with atypical presentation, such as gastritis. Widiastana et al describe the later COVID positive result on patients with gastritis which nonresponsive to general treatment.2 The patients did not have any classical signs and symptoms of COVID-19, hence in the community, misdiagnosis of similar condition might exacerbate the rising infection cases.
A REVIEW OF QUALITY CONTROL IN HISTOCHEMISTRY AND IMMUNOHISTOCHEMISTRY STAINING Yustina Nuke Ardiyan
Berkala Ilmiah Kedokteran Duta Wacana Vol 5, No 2 (2020): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v5i2.180

Abstract

Background: Tissue staining methods need controls to give best quality results. Controls is necessary to support the validity, correctness, and reliability of the staining results. Haematoxylin and Eosin (HE) and immunohistochemistry (IHC) staining require different control quality. Objective: To discuss the utilization of controls used in tissue staining. Method: This is a narrative review with literature from 2008-2016. Results: Routine staining usually does not require any control. Specific stainings require controls to support the validity, correctness, and reliability of the staining results. Histochemistry staining requires only positive control, while positive and negative controls must be included in IHC staining. A tissue section which expresses the protein of interest is reffered to positive control, whereas those without any target antigen expression are defined as negative control. Conclusion: Histochemistry and IHC staining controls are needed to obtain the validity of the tissue or cell samples.
SERIAL IMAGING OF A CHILD WITH LEGG-CALVE-PERTHES DISEASE AT BETHESDA HOSPITAL, YOGYAKARTA: A CASE REPORT Jourdy Kharisma Pradnyana
Berkala Ilmiah Kedokteran Duta Wacana Vol 5, No 2 (2020): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v5i2.162

Abstract

Background: Legg-Calve-Perthes disease (LCPD) is a rare condition of idiopathic avascular necrosis of the femoral head, mostly affects children under fifteen old. Most cases only affect one femoral head; bilateral involvement only occurs in about 15% of cases. Early diagnosis and prompt intervention play an important role in the prognosis to prevent degenerative damage on the bones and joints. Objective: To describe a case of Legg-Calve-Perthes disease in a 9-year-old boy in Bethesda Hospital, Yogyakarta. Case Description: A 9-year-old boy came with one month history of worsening pelvic pain to Bethesda Hospital, Yogyakarta. He also showed limping and limited mobility. Initial imaging studies did not find any abnormalities. Further follow-up with MSCT scan related to the complaint of persistent pain showed defects of left hip joint indicating Legg-Calve-Perthes disease. The patient undergone skin traction treatment which shows modest improvement on serial radiographic examinations during hospital admission. Conclusion: The rarity of LCPD warrant thorough imaging studies on children with unexplainable severe hip joint pain. Treatment should be initiated as early as possible after diagnosis to prevent further bone damage and worsening prognosis. Conservative management with skin traction would benefit the patient in restoring normal anatomy and optimal joint congruence to prevent degenerative damage to the joints.
CHEST IMAGING FOR EARLY DIAGNOSIS OF COVID-19 ON A PATIENT WITHOUT RESPIRATORY SYMPTOMS: A CASE REPORT Wahyu Widiastana; Teguh Kristian Perdamaian; Sutaryanu Dermoredjo
Berkala Ilmiah Kedokteran Duta Wacana Vol 5, No 2 (2020): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v5i2.188

Abstract

Background: The Coronavirus 2019 disease (COVID-19) is transmitted through droplet and aerosol from the respiratory tract of an infected person; and fomites from infected linen and surface. On August 1, 2020, in Yogyakarta, there were 741 confirmed positive cases of COVID-19, and it is still possible to increase. In the time of understanding COVID-19, there are many cases with atypical presentation, including gastrointestinal symptoms. Objective: To describe a COVID-19 case without respiratory symptoms and the role of radiology in detecting COVID-19. Case Description: A 55-year-old male patient came to the hospital complaining of nausea and loss of appetite. Based on the results of the physical examination, there was flatulence. Initial investigations revealed a non-reactive SARS CoV 2 IgG and IgM result. Further non-contrast MSCT Thorax showed infiltrates with bilateral sub-pleural posterolateral consolidation, particularly the left, showing typical pneumonia. Multiple blebs were also found, denoting bronchiectasis. Confirmatory RT-PCR result was positive for SARS CoV 2. Conclusion: COVID-19 usually presents with common respiratory symptoms. However, some patients also experience gastrointestinal symptoms that initially were not detected as COVID-19. In time of COVID-19 pandemic, persistent gastrointestinal symptoms in a high-risk patients warrant further chest imaging and RT-PCR of SARS CoV-2 to detect or exclude the possibility of COVID-19 diagnosis.
EATING HABITS OF OVERWEIGHT CHILDREN AT SEKOLAH DASAR BUDYA WACANA, YOGYAKARTA Raymond Dwi Prasetya; Yoseph Leonardo Samodra; Istianto Kuntjoro
Berkala Ilmiah Kedokteran Duta Wacana Vol 5, No 2 (2020): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v5i2.170

Abstract

Background: Childhood obesity is related to chronic diseases in the future, which could be prevented through changes in eating habit. Strategy in eating behaviour needs an in-depth understanding on contributing factors to unhealthy eating habits in school-age children. Meanwhile, evidence on those factors, especially related increased calorie intake, is still scarce in Indonesia. Objective: This study is aimed to explore the eating habit of primary school students with obesity in a private school in Yogyakarta. Method: A qualitative interview involving parents of obese children was performed at Sekolah Dasar Budya Wacana in January 2020. The transcripts were analysed using a thematic approach to acquire major themes related to the cause of unhealthy eating habits. Results: From 11 parents, there are two major themes developed, which are unhealthy eating habits and parental influences. There are two unhealthy eating habits discovered in this study, which are irregular mealtime and unhealthy food choices. Parental influence which commonly found in children with obesity is permissive parenting style. Conclusion: This study found similar result with previous studies on unhealthy food choices. However, irregular mealtime in this study is not consistent with other literatures which shows a lack of association with childhood obesity, hence need further research to explore the relationship. Permissive parenting style, which commonly found in younger population also play an important role in children unhealthy food choice. This study revealed that health behaviour change strategy in obese children should consider focussing on healthy food preferences with support from parents and family.
CIPLUKAN (PHYSALIS ANGULATA LINN.) EXTRACT AS A NATURAL ADJUVANT REMEDIES FOR SCLERODERMA Lintang Unggul Rini
Berkala Ilmiah Kedokteran Duta Wacana Vol 5, No 2 (2020): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v5i2.235

Abstract

Scleroderma or systemic sclerosis is a rare connective tissue autoimmune disorder.1 Its prevalence in Indonesia is not well recorded but scleroderma is listed as the third most common disease in rheumatology outpatient clinic in Hasan Sadikin Hospital, Bandung, West Java, Indonesia.2,3 Scleroderma is characterized by skin fibrosis, small vessel vasculopathy, and immune system abnormality. The cutaneous lesion of scleroderma is presenting with excessive collagen type-1 production and deposition, as well as exaggerated inflammatory process. There is no specific diagnosis test is available, but in most cases, there are some laboratory findings which support the diagnosis of scleroderma, such as elevated erythrocyte sedimentation rate (ESR), B lymphocyte stimulator (BAFF), C-Reactive Protein (CRP), Soluble Cd40 Ligand (sCD40L), and Procollagen Type-1 N-Terminal Propeptide (P1NP).3-6 The treatment of this autoimmune disease remains a challenge for clinicians. The current treatment for scleroderma is expensive and some side effects as well as drug resistance are reported. Some new medicines are still under research, not accessible, and too expensive for most Indonesian communities. Hence, new therapeutic options are constantly sought.7 Ciplukan herb (Physalis angulate Linn) is a medicinal plant which grows in Indonesia. It has been known for its efficacy and safety as long-term anti-inflammatory, anti-proliferative, and anti-angiogenesis agent.7 Dewi et al conducted a double –blind, randomized clinical trial using ciplukan herb extract as an adjuvant treatment for scleroderma. The clinical trial was performed in Jakarta and Bandung, Indonesia for 2 years. There are 59 scleroderma patients, age 15-60 years old, had stable treatment for at least 3 months, who randomly divided into treatment group (29 people) and control group (30 people). The treatment group received 250 mg ciplukan herb extract three times a day and the control group received 250 mg amylum three times a day for 12 weeks. A 35,9% skin thickness reduction was found in treatment group. It is greater than control group which only gained 6,3% reduction (p
THE POTENTIAL OF RETICULOCYTE HAEMOGLOBIN EQUIVALENT (RET-HE) IN IRON DEFICIENCY ANAEMIA SCREENING AT BETHESDA HOSPITAL, YOGYAKARTA fenty fenty fenty
Berkala Ilmiah Kedokteran Duta Wacana Vol 5, No 2 (2020): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v5i2.177

Abstract

Background: Traditionally, iron deficiency anaemia (IDA) is diagnosed with iron and ferritin status. Ret-He measurement is a promising parameter to detect iron depletion in earlier stages. Previous studies recommended Ret-He examination as IDA screening. Objective: Compare the Ret-He level and iron status of patients with and without IDA at Bethesda Hospital, Yogyakarta. Method: This is a cross-sectional study using laboratory record of haematological examination at Bethesda Hospital from march to August 2019. Erythrocyte indices, iron status and Ret-He measurement was further examined between IDA and non-IDA group by ANOVA, t-test or non-parametric tests. Results: There were 105 samples, where 22 (20.95%) had complete result of Ret-He and iron status, and 10 (45.45%) diagnosed with IDA. The Ret-He level in IDA group is significantly lower than non-IDA group (17.53 ± 2.43 vs 31.50 ± 4.03, p < 0.001). Conclusion: Ret-He level is lower in IDA group, consistent with other biochemical parameters (Serum iron, Serum ferritin, TIBC, and TSAT). This finding might lead to future research on the potential of Ret-He for early detection of IDA in high-risk populations.

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