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Contact Name
Ricko Dharmadi Utama
Contact Email
apinaga53@gmail.com
Phone
+628125173861
Journal Mail Official
thmreditor@gmail.com
Editorial Address
Jl. Kenari 1 RT.8 No.8g Bumi Lingkar Basirih, Banjarmasin, Kalimantan Selatan, Indonesia
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INDONESIA
Tropical Health and Medical Research Journal
ISSN : -     EISSN : 2684740X     DOI : https://doi.org/10.35916/thmr.v1i1
Tropical Health and Medical Research is an open access, peer-reviewed journal that publishing only original research on all aspects of tropical medicine and global health especially health related to the Muslim community. Journal content including viral, bacterial and parasitic infectious diseases, Vectors, Noncommunicable diseases, Epidemiology and population health, Drug, vaccine and diagnostic tool development, Other health issues related to the Muslim community
Articles 6 Documents
Search results for , issue "Vol. 4 No. 2 (2022): Tropical Health and Medical Research" : 6 Documents clear
The Effectiveness of Kirinyuh (Chromolaena odorata L.) Leaf Essential oil as an Antibacterial Staphylococcus aureus and Escherichia coli juwairiah juwairiah; Erfan Roebiakto
Tropical Health and Medical Research Vol. 4 No. 2 (2022): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v4i1.64

Abstract

One of the plants with antibacterial activity is Kirinyuh (Chromolaena odorata L.). The essential oil from these plants has the potential as a natural antibacterial against pathogenic bacteria, such as Staphylococcus aureus and Escherichia coli. This study aims to analyze the antibacterial ability of kirinyuh leaf essential oil (Chromolaena odorata L.) originating from Martapura, Indonesia, by the diffusion method, especially in its ability to inhibit the growth of Staphylococcus aureus and Escherichia coli. The study used five variations of the concentration of essential oils, namely 10 ul, 15 ul, 20 ul, 25 ul, and 30 ul, carried out five times. Essential oil distillation using water and steam distillation method. Antibacterial activity test using well diffusion method. The results showed that the diameter of the inhibition zone against Staphylococcus aureus had a diameter of 9.4mm at a concentration of 10uL, 10.8mm at a concentration of 15uL, 11.6mm at a concentration of 20uL, 13mm at a concentration of 25uL, and 14.4mm at a concentration of 30uL. The diameter of the inhibition zone against Escherichia coli had a diameter of 11.6mm at a concentration of 10uL, 12.8mm at a concentration of 15uL, and 14mm at a concentration of 20uL, 14.8mm at a concentration of 25uL, 15.8mm at a concentration of 30uL. Conclusion The most significant inhibition zone of kirinyuh leaf essential oil (Chromolaena odorata L.) against Staphylococcus aureus was 14.4mm at a concentration of 30uL and against Escherichia coli was 15.8mm at a concentration of 30uL. Further research is needed on the antibacterial effectiveness of kirinyuh leaf essential oil (Chromolaena odorata L.) against other types of bacteria and also against antibiotic-resistant bacteria.
Utilization of Natural Dyes Solutions and Glycerol for the Quality and Durability of Direct Wet Mount Preparations Storage in Educational Laboratories Iswiyanti Novita; Linda Yuliana
Tropical Health and Medical Research Vol. 4 No. 2 (2022): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v4i1.65

Abstract

Educational laboratories require the availability of direct wet mount preparations that can last a long time with good quality. Various studies have mentioned techniques so that preparations can last a long time. This study aims to analyze the composition of dyes and glycerol in wet preparations of worm eggs on the quality and shelf life of the preparations. The solvent variations used for the wet preparations were Angkak 2%, and eosin 2%, with the addition of variations in the concentration of glycerol 20%-45%. The number of treatments and repetitions in the study was 70 samples, which were observed in the first, second, third, and fourth weeks. Based on the ANOVA test, the results showed a significant effect on the parameters measured, namely the type of dye, the type of slide, and the shelf life of the preparation (storage) in natural dye solution (2% ethanol extract of Angkak solution) and synthetic dye solution (2% eosin solution). The correlation test results of storage time treatment on the clarity of the preparations showed that the longer the storage, the lower the clarity of the preparations (r=-0.46246). The correlation test results of storage time treatment on the contrast of the preparations showed that the longer the storage, the less the contrast was not so strong (r=-0.26375). The correlation test results of storage time treatment on the quality of the preparations showed that the longer the storage, the lower the quality of the preparations (r=-0.51346). The conclusion is that the best quality of wet preparations is preparations that are stored for four weeks using a flat object-glass with a mixture of 1:1 dye solution of 2%-glycerol solution of 35% and 1:1 mixture of a 2%-glycerol solution of 1:1 solution. Further research is needed on the concentration of the dye solution mixture to find the best formulation for improving the quality and resistance of wet preparations.
Analyzes of Knowledge, Attitude, and Practice of Turkish Midwives and Puerperal Women Regarding Pharmacovigilance Yusuf Ergün; Eylem Toker; Mine Akben; Tansel Bekiroğlu Ergün
Tropical Health and Medical Research Vol. 4 No. 2 (2022): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v4i1.67

Abstract

Spontaneous reporting of adverse drug reactions (ADRs) is the backbone of the pharmacovigilance system. However, underreporting is still a fundamental hurdle around the globe that must be resolved. To analyze Turkish midwives' and puerperal women's knowledge, attitude, and practice regarding pharmacovigilance. A cross-sectional study on midwives (n=36) and puerperal women (n=227) was carried out from September 2019 to June 2020 in a State Hospital in Turkey. Data were collected by a questionnaire and analyzed by Mann-Whitney U, Kruskal-Wallis, and the Chi-Square tests. The knowledge level of midwives was significantly higher than that of the puerperal women. Although all midwives knew of adverse drug reactions, only half of the puerperal women had heard this. The awareness of the pharmacovigilance term was 97% and 2% in midwives and puerperal women, respectively. Similarly, 81% of the midwives were aware of the Turkish Pharmacovigilance Center (TPC), whereas only 1% of the puerperal women realized the fact. More than half of the midwives knew they could directly report ADRs to TPC. However, most did not know how they could send or report ADRs. Interestingly, only five midwives knew that congenital anomalies and congenital disabilities had been included in ADRs. Although the knowledge, attitude, and practice of Turkish midwives were significantly better than puerperal women regarding pharmacovigilance, it is apparent that both groups were insufficient to get involved in the pharmacovigilance system properly.
Another Reason for Vaccine Hesitancy in Turkey: Siblings with Autism Spectrum Disorder Semra Bayturan; Nesrin Şen Celasin
Tropical Health and Medical Research Vol. 4 No. 2 (2022): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v4i2.69

Abstract

Despite studies showing no link between the measles-mumps-rubella vaccine and autism spectrum disorder (ASD), the belief that the vaccine causes autism can still affect parents' attitudes towards vaccines. This study aimed to investigate the vaccination status, vaccine information source, and the factors related to vaccine hesitancy diagnosed with ASD and their younger siblings based on interviews and questionnaires. A questionnaire was performed on 37 ASD groups (parents of children with ASD and their younger siblings) and 65 control groups (families with healthy children and healthy younger siblings). The research was conducted between 1st January 2019 and 31st December 2019. Incomplete vaccination was found higher in both children with ASD(n=37) and their younger siblings compared to the healthy control group(n=65) (p=0.045; p=0.016). The four children (10.8%) diagnosed with ASD had five siblings with incomplete or missing vaccinations. Families with children with ASD stated that their knowledge of vaccines was sufficient compared to the control group (p=0.021). All parents stated the autism vaccination relationship as the reason for incomplete vaccination. Parents of children with ASD may delay or reject vaccination for their children and their younger siblings.
Seroprevalence of Leptospirosis in Suspected High-Risk Sudanese Patients; A Pilot Exploratory Study Nada Abdelghani Abdelrahim; Wisal Mustafa Ibrahim Mohammed
Tropical Health and Medical Research Vol. 4 No. 2 (2022): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v4i2.71

Abstract

The extent of leptospirosis is unknown in Sudan, and it might be mistaken for other more common febrile infectious diseases. Leptospirosis might also be associated with renal diseases that are common in Sudan. We intended to explore the existence of human leptospirosis in suspected high-risk patients in Khartoum, Sudan, via sero-screening random febrile patients and those undergoing renal dialysis. This pilot exploratory study was conducted over six months, from April to September 2013. Four hospitals were selected conveniently following a non-random sampling approach. One hundred nineteen febrile patients (with or without definitive diagnosis) and patients under renal dialysis were included, and their serum specimens and clinical and demographic data were collected. Sera were screened qualitatively for the existence of anti-leptospiral IgM antibodies using a rapid lateral flow immune-sorbent assay. Ethical clearance and official permissions were obtained. Of the 119 patients, 57 (47.9%) had end-stage renal disease. They were under dialysis at Renal Dialysis Unit in Asbab Charity Hospital in Bahri, 47 (39.5%) were febrile with unknown origin attending the Tropical Medicine Hospital in Omdurman, and 15 (12.6%) were febrile and were diagnosed as having malaria or typhoid and attended Yastabshiron Medical Centre and Bashauer Teaching Hospital. The prevalence of anti-leptospiral IgM antibodies among all 119 screened patients was 7%. The prevalence among the 57 with the end-stage renal disease was 9%, and among the 47 with a fever of unknown origin was 6%. The prevalence among the 15 with a fever of known origin (diagnosed as malaria or typhoid) was 0%. Almost all positive patients had recurring episodes of fever, were in close contact with livestock, were farmers, and had an untreated natural source for drinking water. Human leptospirosis does exist in this targeted population. It is probably a common febrile condition and can be easily considered one of the major causes of chronic kidney disease affecting people in Sudan. A national sero-screening for leptospirosis among those living in high-risk geographical areas and those at occupational risk is highly recommended.
The Covid-19 Disease in Pediatric Cancer Patients: A Single Center Experience Özlem Terzi; Hüseyin Avni Solgun; Nuran Karabulut; Sibel Tekgündüz; Fatma Sek; Cengiz Bayram; Ali Ayçiçek
Tropical Health and Medical Research Vol. 4 No. 2 (2022): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v4i2.73

Abstract

Children with cancer can have a severe disease when infected with respiratory viruses. In this study, we aimed to understand the clinical course and outcomes of SARS-CoV-2 infection in children with cancer. Data evaluated about laboratory-confirmed SARS-CoV-2 infections in sixty-three children (<18 years) with cancer between 01.06.2020 - 01.08.2021 were retrospectively reviewed. Data for demographics, oncological diagnosis, clinical course, and cancer therapy details were collected. Primary outcomes were disease severity and modification to cancer-directed therapy. The median (range) age was 7.6 ± 5.3 (0-18) years, and the most common underlying diagnosis was leukemia (74.6%). The most common symptom was fever (67.7%), and most patients had symptoms (70%). The mild disease was most common (60.3%). During Covid-19 infection, disease severity increased 23 times (p=0.003) in those with fever and 4.083 (p=0.045) in those with neutropenia. It was observed that the severity of the disease increased 2.589 times as CRP increased (p<0.001). However, few patients (9.5%) were admitted to the intensive care unit. Five patients died, but none of the deaths could be attributed to Covid-19 alone. Most patients did not experience chemotherapy treatment interruption (57%). When interruption did occur, this duration was 13.9±14.3 (1.0-60.0) days. In this cohort of pediatric oncology patients, nearly 43% of patients who had Covid-19 were their chemotherapy interrupted. Future studies will only reveal the final effect of the pandemic on childhood cancer.

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