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Bayu Brahma
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journal.cancer@gmail.com
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National Cancer Center - Dharmais Cancer Hospital Research and Development Building, 3rd-floor Jl. Letjen S. Parman Kav. 84-86, Slipi West Jakarta
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INDONESIA
Indonesian Journal of Cancer
Published by National Cancer Center-Dharmais Cancer Hospital
ISSN : 19783744     EISSN : 23556811     DOI : https://www.doi.org/ 10.33371
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health
Indonesian Journal of Cancer is a peer-reviewed and open-access journal. This journal is published quarterly (in March, June, September, and December) by Dharmais Cancer Hospital - National Cancer Center. Submissions are reviewed under a broad scope of topics relevant to experimental and clinical cancer research. Articles are original research that needs to be disseminated and written in English. All submitted manuscripts will go through the double-blind peer review and editorial review before being granted acceptance for publication. The journal publishes original research articles, case reports, and review articles under the following categories: cancer management, cancer prevention, cancer etiology, epidemiology, molecular oncology, cancer diagnosis and therapy, tumor pathology, surgical oncology, medical oncology, radiation oncology, interventional radiology, as well as early detection.
Arjuna Subject : Kedokteran - Onkologi
Articles 12 Documents
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Search results for , issue "Vol 16, No 3 (2022): September" : 12 Documents clear
Ventriculography Modality in Detection and Evaluation of Cardiotoxicity in Breast Cancer Patients Receiving Chemotherapy: A Literature Review
Indonesian Journal of Cancer Vol 16, No 3 (2022): September
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v16i3.897

Abstract

Background: Ventriculography or Multigated Acquisition Scanning (MUGA) has been the gold standard for baseline and serial assessment of Left Ventricular Ejection Fraction (LVEF) for cardiotoxicity since 1970. However, several modalities have been proposed to substitute Ventriculography. This study aimed to find out whether Ventriculography can still be considered the gold standard to monitor and detect cardiotoxicity before, during, and after administration of the chemotherapy and compare Ventriculography with Cardiac Magnetic Resonance (CMR) and Echocardiography (Echo).Methods: A literature review was done by searching original literature with keyword combinations on PubMed, Cochrane, and ClinicalKey in the past five years (2016–2021) with language restrictions only in English. Of 1,381 pieces of literature, five pieces are included to review in this study. Results: Ventriculography has high sensitivity and specificity in monitoring and detecting cardiotoxicity. Other modalities are CMR and Echo. CMR is more accurate although it is costly whilst Echo has high interobserver variability. Ventriculography and CMR have not shown interchangeable results. The literature also shows that Ventriculography could evaluate cardiotoxicity by assessing diastolic function. Conclusions: Ventriculography can still be used as the gold standard for monitoring cardiac function and detecting cardiotoxicity at an affordable price and with acceptable side effects. It recommends choosing only one modality for serial monitoring due to not interchangeable results among modalities
Analysis of Dominant Factors that Effect Delayed Diagnosis in Women with Breast Cancer in Baladhika Husada Hospital Jember
Indonesian Journal of Cancer Vol 16, No 3 (2022): September
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v16i3.883

Abstract

Background: Delayed diagnosis will have an impact on poor prognosis and complicate the treatment of breast cancer, contributing to low life expectancy for breast cancer patients. The study aims to find the factors that play the most role in influencing the behavior of women with breast cancer as well as dig deeper into the things behind the patient in making decisions that have an impact on delayed diagnosis. Methods: The study uses an analytical observational design with quantitative and qualitative mixed methods. Collecting data was conducted from April until June 2021 on 76 women with breast cancer at Baladhika Husada Hospital Jember based on classification into case and control groups. The sampling method used purposive sampling and the Lemeshow formula. Results: The results showed the factor that dominates the occurrence of delayed diagnosis is alternative medicine (p = 0.013; OR 11.03). Based on the results of the study, patients who undergo alternative medicine are 11 times more at risk of delayed diagnosis of breast cancer compared to patients who do not undergo alternative treatment.Conclusions: The patient’s background in choosing alternative medicine is supported by various reasons including concerns about medical treatment methods, concerns about nominal medical costs, and negative information from the surrounding. Thus, it can be concluded that the dominant factor affecting the delay in the diagnosis of women with breast cancer is alternative medicine.

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