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SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN
ISSN : 20851545     EISSN : 2339093X     DOI : -
Core Subject : Health,
Sains Medika is journal of medicine and health, is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from Biomedical Sciences, Public Health, Clinical Sciences, and Medical Education to integrate researches in all aspects of human health. This journal publishes original articles, reviews article, and also interesting case reports.
Arjuna Subject : -
Articles 207 Documents
Problem Based Learning (PBL) in Competence Based Curriculum and The Accademic Achievement: Evaluation of PBL Implementation Kusumawati, Wiwik
Sains Medika : Jurnal Kedokteran dan Kesehatan Vol 4, No 1 (2012): Januari-Juni 2012
Publisher : Fakultas Kedokteran; Universitas Islam Sultan Agung (UNISSULA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (158.022 KB) | DOI: 10.30659/sainsmed.v4i1.382

Abstract

Background: Medical Faculties in Indonesia has implemented problem based learning (PBL) in competence based curriculum as a learning strategy. The aim of this study is to know the effect of PBL method on academic achievement and factors affecting successfull PBL implementation.Design and Method: This study used quantitative and qualitative method. Data collection method is by distributing questionnaires, focus group discussion (FGD) and document analysis of students’ academic achievement. This study included 3 year level students (2004, 2005, 2006) using PBL in school of medicine faculty of medicine and health sciences UMY (FMHS UMY).Result: GPA average > 2.5 is 32.47 %, MCQ > 60 is 33.1% and OSCE is 92.8%. The role of tutor and also practical instructor to facilitate learning objective was not optimal. The factors for the poor implementation of PBL includes curriculum planning (understanding of PBL concept and dissemination of curriculum), implementation of curriculum (various of block load, opportunity for self directed learning, e-learning effectivity, etc) and assessment system (the number of students who reach minimal standar of MCQ is low, validity of MCQ is also low, etc).Conclusion: This study suggest the need to improve planning, implementation and curriculum assessment to support implementation of PBL. The role of Lecturer, tutor and practical instructor should be improved through faculty development to faciliate teaching learning proccess in PBL method (Sains Medika, 4(1):30-38).
The Difference in The Effect Between The Oxygenated and Mineral Water on The O2 Saturation And Urine pH Ellyana, Naila Shulya; Sarosa, Hadi; Hussaana, Atina
Sains Medika : Jurnal Kedokteran dan Kesehatan Vol 3, No 2 (2011): Juli-Desember 2011
Publisher : Fakultas Kedokteran; Universitas Islam Sultan Agung (UNISSULA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (161.232 KB) | DOI: 10.30659/sainsmed.v3i2.399

Abstract

Background: During exercise, oxygen decreases due to acidosis leading the production acid urine by kidney. Oxygenated water having capability to absorb more oxygen compared to mineral water is used to meet the oxygen need during exercise. This study investigated the effect of oxygenated water and mineral water on the O2 saturation and urine pH.Design and method: In this crossover study, 46 subjects were randomly assigned to either oxygenated water or mineral water for 24 hours followed by a crossover to the other regimen for an additional 24 hours of treatment. After 100 m sprint running for 20 minutes, the oxygen saturation and urine pH of the subjects were assessed.Result:The mean oxygen saturation before and after the treatment of oxygenated water were 96.78±1.32 and 97.61±0.93 respectively. The mean oxygen saturation before and after the mineral water treatment was 97.35±0.85 and 97.01±1.04 respectively. The urine pH after the administration of oxygenated water and mineral water were 6.643±0.69 and 6.585±0,58 respectively. Wilcoxon test resulted in no significant difference in pH after the treatment of oxygenated water and mineral water (p=0.498). Urine pH after the treatment of oxygenated water was found to be higher compared to that of mineral water.Conclusion: the oxygenated water increases the O2 saturation and urine pH compared to mineral water (Sains Medika, 3(2):162-167).
The Difference in Effectiveness of 70% and 0.5% Chlorine to ReduceThe Germ Number on Stethoscope’s Membrane Experimental research at stethoscope in Baitul Izah Ward of Sultan Agung Islamic Hospital Semarang Pramita, Heny; Saugi Abduh, Saugi Abduh; Chodidjah, Chodidjah
Sains Medika : Jurnal Kedokteran dan Kesehatan Vol 3, No 1 (2011): Januari-Juni 2011
Publisher : Fakultas Kedokteran; Universitas Islam Sultan Agung (UNISSULA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (139.515 KB) | DOI: 10.30659/sainsmed.v3i1.410

Abstract

Background: Recently, nosocomial infection (hospital- acquired infections) is estimated to affects more than 1.4 million of in patients in all over the world. Stethoscope is one source of nosocomial infection caused by the continuous contact from one patient to another. 70% alcohol and 0.5% chlorine can be used for disinfection. The purpose of the research is to find out the difference in the effectiveness of 70% alcohol and 0.5% chlorine to reduce the amount of germ on the stethoscope’s membrane.Design and Methods: This was an experimental research with the Post Test Only Control Group Design using 18 stethoscopes divided into 3 groups randomly. Group A was the control group (aquabidest), group B were treated with 70% alcohol treatment, and group C was treated with 0.5% chlorine. The research samples were the stethoscopes used to treat patient in Baitul Izah ward of Islamic Hospital of Sultan Agung Semarang. The data on the germ amount was analyzed using Kruskal-Wallis test. Results: There was a significant difference between aquabidest group and 70% alcohol group (p<0.05) and between aquabidest control group and chlorine group(p>0.05), nevertheless, there was no significant difference between the 70% alcohol group and 0.5% chlorine group ( 0.652). Conclusion: There was no difference in the effectiveness between 70% alcohol and 0.5% chlorine to reduce the number of germ on the stethoscope’s membrane (Sains Medika, 3(1):63-68).
The Effect of Propolis Extract on MDA Levels (Malondialdehyde) and Sperm Quality on Epididimis (Experimental Study on Wistar Strain Male Rats Exposed to Kretek Cigarettes) Hoesada, Ivan; Nasihun, Taufiqurrahman; Isradji, Israhnanto
Sains Medika : Jurnal Kedokteran dan Kesehatan Vol 7, No 1 (2016): January - June 2016
Publisher : Fakultas Kedokteran; Universitas Islam Sultan Agung (UNISSULA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1203.185 KB) | DOI: 10.30659/sainsmed.v7i1.1165

Abstract

Introduction: Cigarette smoke exposure increase free radicals and effecting male infertility. Propolis is commonly used as supplement to increase antioxidant levels. Objectives: To prove the effect of propolis extract to MDA level and spermatozoa quality on epididymis due to cigarette smokes. Methods: Experimental research post test only control group design using 30 male rats Wistar Strain, 8 weeks old, weighed 200 – 250 gram, randomly divided into 5 groups. K-1 (normal), do not received propolis and cigarettes smoke; K-2 (negative control) exposed to cigarettes smokes 4 buds/ day, did not received propolis; K-3, K-4, and K-5, apart from cigarrete smokes 4 buds/day each were given propolis with 2.9 mg, 5.4 mg, dan 8.3 mg/200g body weight/day for 21 days. On the 22nd day, rats were sacrificed, sperms were extracted from cauda epididymis, and then examined for MDA and sperm quality. Statistical analysis used was one way ANOVA, continued with post hoc LSD with significance level of p<0,05. Results: ANOVA test on MDA level and sperm quality between groups showed significant difference of, p = 0.005. Post hoc test indicated that MDA on K-5 (1,12) is significantly lower compare to K-2 (5,89), p = 0,001. As well as consentration, motility and morphology (spermatozoa quality) which indicated that K-5 (49.32, 64.15, 36.34) is significantly higher compared to K-2 (22.62, 27.27, 21.39), each with p value of p = 0.001.Conclusion: extract propolis 8,3 mg/day for 21 days is proven to increase spermatozoa quality and lower the MDA level on male rats wistar strains’ epididimis exposed to cigarettes smoke.
Uji Efikasi Obat Nyamuk Bakar dengan D-Allethrin 0,2% terhadap Vektor Malaria di Desa Gembong, Kecamatan Kandangserang, Kabupaten Pekalongan
Sains Medika : Jurnal Kedokteran dan Kesehatan Vol 1, No 1 (2009)
Publisher : Fakultas Kedokteran; Universitas Islam Sultan Agung (UNISSULA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v1i1.1678

Abstract

Development of Anti Acne Cream (w/o/w Multiple Emulsion) Containing Green Tea Leaf Waste Widyaningrum, Naniek
Sains Medika : Jurnal Kedokteran dan Kesehatan Vol 8, No 2 (2017): July-December 2017
Publisher : Fakultas Kedokteran; Universitas Islam Sultan Agung (UNISSULA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (260.644 KB) | DOI: 10.30659/sainsmed.v8i2.2030

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Background: To date, green tea leaf waste is not well utilized, the waste is remain considered as a waste. Previous studies found that green tea leaf waste still have a fairly high EGCG content. EGCG has benefits as an antibacterial. Utilization of green tea leaf waste started from formulation until the diversification of multiple emulsion w/o/w products has not been reported.Objective: To develop anti acne cream (W/O/W) multiple emulsion containing green tea leaf waste and evaluate its antibacterial activity against acne-inducing bacteria of Propionibacterium acnes (P.acnes).Methods: Phase one of this research was green tea leaves was extracted by infundation and fractionation method using ethyl acetate and prepared in different concentration (1% to 6%). The second stage was ethyl acetate fraction of green tea leaf extract was tested for its antibacterial activity against P.acnes. Third stage was tested physical properties of formulation with w/o/w multiple emulsion.Results: The optimal antibacterial activity of ethyl acetate fraction of green tea leaf extract against P.acne was at the concentration of 6%, with inhibition zone of 32.6 mm ±0.57. The formula of w/o/w multiple emulsion loaded with green tea leaves waste of 6% active substance demonstrated a good physical properties which can spread 90.4 cm2 ± 0.03, pH 5.00 ± 0.02 and microscopic analysis showed multiple emulsion w/o/w.Conclusion: The concentration of 6% green tea leaf waste formulated in multiple emulsion had a good physical and antibacterial activity for a referred standard. It is necessary to test the stability of multiple emulsion formula.
Overview of The Incidence and Risk Factors for Nosocomial Infections Using a Geographic Information System Maps Setianto, Rochady; Lazuardi, Lutfan; Dahesihdewi, Andaru
Sains Medika : Jurnal Kedokteran dan Kesehatan Vol 5, No 2 (2013): July-December 2013
Publisher : Fakultas Kedokteran; Universitas Islam Sultan Agung (UNISSULA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1071.366 KB) | DOI: 10.30659/sainsmed.v5i2.345

Abstract

Hospitalized patients have a high risk of getting nosocomial infections due to various reasons. They tend to be more susceptible to infection because oftheir underlying disease condition, and they have higher when patients undergo invasive procedures. If the patient’s immune system is impaired, thenon-pathogenic microorganism are capable of causing disease. Map is a method of illustrating an epidemiologic effectively . Maps can be used to showplace of incidence. Mapping the incidence of nosocomial infections in Sultan Agung Hospital is a method developed for the surveillance of nosocomialinfections. This type of research is a quantitative study with a cross sectional design. This study illustrates the risk factors of nosocomial infection withincidence of nosocomial infections that occur based on time point. Risk factors are extrinsic and intrinsic factors. Based on the spatial image on the map,in extrinsic incidence of nosocomial infections is Plebitis. Genesis Plebitis incidence correlates with the placement of hand washing points handrub. Whilethe intrinsic factor in the Plebitis image and ILO most inpatient distribution in patients aged 50 years with impaired skin integrity due to infusion andphysically due to decreased immunity associated with a variety of underlying diseases. Incidence of nosocomial infections in the inpatient unit is theprimary predisposing factors such as age and clinical issues related predisposing underlying disease can weaken the immune system of the patient, so thatthe procedures and even the most basic medical treatment could potentially cause nosocomial infection.
Comparison of Serum Interleukin-6 (Il-6) Levels Between Patients With HELLP Syndrome Versus Normotensive Pregnant Ganap, Eugenius Phyowai; Sofoewan, Sulchan; Siswosudarmo, Risanto
Sains Medika : Jurnal Kedokteran dan Kesehatan Vol 9, No 2 (2018): July-December 2018
Publisher : Fakultas Kedokteran; Universitas Islam Sultan Agung (UNISSULA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (727.341 KB) | DOI: 10.30659/sainsmed.v9i2.3630

Abstract

Background: Interleukin-6 (IL-6) has been known associated with oxidative stress and endothelial dysfunction, and also has important roles in pathogenesis of preeclampsia. Several studies have demonstrated that there was a significant increase of serum IL-6 levels in preeclamptic compared to normotensive pregnant women. However, study to evaluate serum IL-6 level in pregnant women with HELLP (hemolysis, elevated liver enzyme, and low platelet) syndrome is not well documented yet. This study aims to evaluate serum IL-6 levels between women with HELLP syndrome compared to normotensive pregnant.Methods: The research design was observational cross-sectional study. Samples were recruited consecutively using inclusion and exclusion criteria from emergency department and inpatient wards at Dr. Sardjito General Hospital, Yogyakarta, Indonesia. Serum IL-6 were collected from venous blood sample and measured by enzyme-linked immunoassay (ELISA) method. Independent-samples t-test or Mann-Whitney test was used to compare serum IL-6 values between women with HELLP syndrome and normotensive pregrnancy. A statistical measurement conducted using SPSS IBM Statistics 19® and considered significance when p<0,05.Results: There were 46 subjects, consisted of 23 women with HELLP syndrome and 23 women with normotensive pregnancy. Serum IL-6 level was a mean of 0,11±0,08 pg/mL and 0,15±0,20 pg/mL in women with HELLP syndrome compared to normotensive pregnancy respectively. There was no significant statistical difference between both groups (p=0,17).Conclusion:.The result of this study has shown that no significant difference of serum IL-6 level in HELLP syndrome women compared to normotensive pregnant women. 
The Correlation between Mothers’ Knowledge and Attitude following Posyandu and Weight Gain in Children Aged 2-3 Years in Sawah Besar Village, Gayamsari District of Semarang Fitriyani, Anis; Indrawati, Nuke Devi
Sains Medika : Jurnal Kedokteran dan Kesehatan Vol 5, No 1 (2013): January-June 2013
Publisher : Fakultas Kedokteran; Universitas Islam Sultan Agung (UNISSULA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (638.794 KB) | DOI: 10.30659/sainsmed.v5i1.361

Abstract

Minister of health decree No. 1457/ MENKES/ SK/ 2003 states that the minimum service standard in health sector for growth monitoring activitiesat integrated service post (Posyandu) in the office of Semarang Municipality targeted 80.17% children gain wight. But the gaining weight infants in the District Gayamsari were 72.09%.The study seeks to know the corelation between the level of knowledge and atittude of mothers following Posyandu and weight gain in children aged 2-3 years in the Sawah Besar Village Gayamsari District of Semarang. This study was a cross-sectional study a using a questionner. A sample were 87 mothers who had children aged 2-3 years in the Village and following the Sawah Besar Posyandu from total population 690 children were selected using a proportionate random stratified sampling method. The finding indicates that 46 % mothers had enough knowledge 48.3% mothers showed ‘not good’ attitute. Most of the children (59.8%) did not gain weight. There was a correlation between the mothers’ level of knowledge and attitute and the weight gain in children aged 2-3 years.
Lip Reconstruction Using Radial Forearm Freeflap After Radical Excision of Squamous Cell Carcinoma: A Case Report Setiawan, Eko; Sari, Erythrina Permata
Sains Medika : Jurnal Kedokteran dan Kesehatan Vol 10, No 2 (2019): July-December 2019
Publisher : Fakultas Kedokteran; Universitas Islam Sultan Agung (UNISSULA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (712.718 KB) | DOI: 10.30659/sainsmed.v10i2.1661

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INTRODUCTION: The main treatment modality for squamous cell carcinoma of the head and neck is by surgical wide excision. Post-excision reconstructive surgery is essential for restoring aesthetics and function. Fasciocutaneous free-flap is an acceptable method for reconstructing a wide lession of the face since the technique does not cause significant morbidity.CASE REPORT: A 41 year-old female was diagnosed with squamous cell carcinoma (T3N0M0) of the inferior lip after achieving tumor-free margin radical excision. Reconstruction of the defect was made with radial forearm freelap followed by a three-phase refinement flap. The patient was left with a aesthetically acceptable lip without other facial morbidity.DISCUSSION: Reconstructive surgery following a widely excised tumor of the lips requires special attention because of its important physical and aesthetical role. Radial forearm freeflap causes minimal facial morbidity since the technique does not require donor tissue from the face. Other benefits include adequate tissue thickness, minimal contracture and unaltering skin color. Further refinement flaps is needed to complete the reconstruction process.CONCLUSION: Radial forearm free flap is a good choice for reconstruction a wide lession following a wide excision of lip tumor.

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