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Journal of International Surgery and Clinical Medicine
Published by Universitas Syiah Kuala
ISSN : -     EISSN : 28077008     DOI : https://doi.org/10.51559/jiscm
Core Subject : Health,
Health Professions Medicine & Pharmacology
Journal of International Surgery and Clinical Medicine; peer-reviewed journal aiming to communicate high-quality research articles, reviews, and general articles in the field. JISCM publishes articles that encompass basic research/clinical studies related to Surgical Oncology, Digestive Surgery, Vascular Surgery and Endovascular, Pediatric Surgery, Urology, Neurosurgery, Orthopedics, Plastic Surgery. The Journal aims to bridge and integrate the intellectual, methodological, and substantive diversity of medical scholarship and encourage a vigorous dialogue between medical scholars and practitioners.
Arjuna Subject : Kedokteran - Pembedahan
Articles 5 Documents
 1 
Search results for , issue "Vol. 2 No. 1 (2022): Available Online: June 2022" : 5 Documents clear
The role of ROS1 mutation in non-small cell lung cancer Novita Andayani; Basti Handoko; Murtaza
Journal of International Surgery and Clinical Medicine Vol. 2 No. 1 (2022): Available Online: June 2022
Publisher : Surgical Residency Program Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jiscm.v2i1.15

Abstract

Lung cancer is a malignancy of the lung organs consisting of primary lung cancer originating from lung epithelial cells and metastatic lung cancer originating from other organ cancers that spread. In lung cancer, the vast of recent studies investigated the role of molecular alterations in patients. Molecular characterizations of lung cancer give further information in order to better diagnosis, prognostic, and therapeutic implications in patients. c-ROS oncogene 1 (ROS 1) is naturally expressed by healthy and normal cells arranged in human chromosomes. The role of ROS1 in its normal development is not fully understood. Point of view in oncology ROS1 expressed normally is referred to as inactive ROS1. Mutated ROS1 due to fusion with a specific gene produces tyrosine kinase receptors on the surface of the cell that has the advantage of sending signals into the cells to induce growth factors and proliferation of ROS1. Although the prevalence of ROS1 rearrangement was low, the parallel with Non-Small Cell of Lung Cancer (NSCLC), the most dominant lung cancer, indicating the number of ROS1 mutation patients also increased. The challenge of diagnosing ROS1 mutation by Immunohistochemical (IHC) ROS1 is only a screening method and confirmed by fluorescence in situ hybridization (FISH) examination. The appropriate therapy regimen for positive ROS1 mutation will increase the survival rate in lung cancer patients.
Herpes Zoster on a bladder cancer patient – a rare case Dhelya Widasmara; Adya Sitaresmi; Santosa Basuki; Besut Daryanto; Kurnia Penta Seputra
Journal of International Surgery and Clinical Medicine Vol. 2 No. 1 (2022): Available Online: June 2022
Publisher : Surgical Residency Program Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jiscm.v2i1.21

Abstract

Introduction: Herpes zoster (HZ) is caused by reactivation of latent varicella-zoster virus (VZV) infection due to disturbance in T-cell mediated immunity. Risk factors include malignancy and therapy related to malignancy. Bladder cancer has a moderate association with HZ, with a risk increment of 10-50%. The rate of HZ in bladder cancer patients is 8/1000. Case description: A 57-years-old man with bladder cancer T4bN3M0 complained of a painful erythematous vesicular rash on the left front abdomen extended to the back 1 week prior, accompanied by fever and burning sensation. He has had regular chemotherapy using Gemcitabine and Cisplatin, and radiotherapy with 2 Gray doses each session. Dermatological examination showed multiple well-defined erythematous-based vesicles, clustered on the left abdominal, flank, and posterior thorax region at T7-T9 dermatome. Tzanck-smear examination showed multinucleated giant cells. The patient was given acyclovir, paracetamol, and wet dressing on vesicles. His chemoradiotherapy was also halted. On the 7th day of evaluation, there were no new lesions and his complaints improved. In cancer patients, CD4+ and CD8+ levels decreased, accompanied by lymphocyte proliferation impairment. Cytotoxic chemotherapy agents work by attacking proliferation cells, affecting immune-related cells. Ion radiation in radiotherapy interferes with a regional cellular immune response that inhibits viral reactivation. Conclusion: Principal HZ management in cancer patients includes antiviral and analgesics. In cancer patients, the occurrence of HZ can disturb and postpone management related to malignancy. The postponement of chemoradiotherapy is based on the patient's conditions and the severity of the disease.
Surgical Plate Fixation of Simple Rib Fractures: A Case Report Ronald Winardi Kartika
Journal of International Surgery and Clinical Medicine Vol. 2 No. 1 (2022): Available Online: June 2022
Publisher : Surgical Residency Program Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jiscm.v2i1.22

Abstract

Introduction:  Rib fractures can cause patient morbidity that causes long hospitalization if conservative treatment is carried out. Current international guidelines recommend a minimally incisional surgical-based treatment approach to reduce pain and provide optimal clinical benefit. Numerous studies have demonstrated that surgical fixation in conjunction with multidisciplinary integrated care pathways offers the highest therapeutic benefit for developing countries, which are typically more accountable for a higher share of unfavorable global outcomes. This case report describes the selection of appropriate decision-making in the management of multiple rib fractures. Case description: We report that a 51-year-old, still actively working young female came to our emergency department after a motorcycle accident, left chest hitting the road boundary, 2 days earlier. He presented with severe upper chest pain, chest deformity, mild dyspnea, tachycardia, subcutaneous emphysema, and hematoma. The chest radiograph shows a hypo ventilated lung field and a minor pleural effusion. A computed tomography scan showed right lateral rib fractures 3–4 posterior and 5–6 posterolateral, with areas of hyperdensity of simple bone fragments, and pulmonary contusion. Treatment consists of minimal incision with surgical fixation of the 5th and 6th posterolateral ribs which causes pain. For rib fractures 3-4, because it is stable and protected by the scapula, we only perform conservative measures. Rib fixation uses titanium reconstruction plates and cortical fixing screws. The patient's clinical condition improved rapidly postoperatively with a length of stay of 2 days after surgery. Follow-up at 6 weeks, the patient confirmed a full return to preoperative daily activities with the return to normal work activities as well as high quality of life. Conclusion: In this case report, reported that in rib fractures in a developing country, thoracic trauma can be treated through medical treatment with minimal incisions which allows rapids recovery of the patient.
Relationship of eating habits to acute appendicitis in children: a literature review Rizkiasa Nurafitha; Dian Adi Syahputra; Rima Novirianthy; Husnah; Munthadar
Journal of International Surgery and Clinical Medicine Vol. 2 No. 1 (2022): Available Online: June 2022
Publisher : Surgical Residency Program Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jiscm.v2i1.24

Abstract

Introduction: Appendicitis is the inflammation of appendix vermiformis and is designated a national health priority issue by the Ministry of Health. Obstruction of the appendicitis lumen is the main etiology of acute appendicitis, and one of the risk factors is eating habits. This study aimed to determine how eating habits are at risk of causing appendicitis in children. Eating habits that were becoming the focus of this study are fiber intake, water consumption, and fast food. Methods: This research is a literature study with the scoping review method, compiled based on PRISMA-ScR. Results: The results obtained are four works of literature stating that low fiber intake and inadequate water consumption in children have a relationship with acute appendicitis, and one piece of literature states that there is no correlation. However, the consumption of fast food has no direct relationship to the occurrence of appendicitis. Conclusion: In this review, a low-fiber diet was significantly correlated with an increased incidence of appendicitis in children.
Risky sexual behavior and prevention of STIs in female merchants based on behavioral theory of health belief model: an exploratory study in Denpasar city, Bali Luh Gede Pradnyawati; Dewa Ayu Putu Ratna Juwita; Anny Eka Pratiwi; Ni Made Hegard Sukmawati
Journal of International Surgery and Clinical Medicine Vol. 2 No. 1 (2022): Available Online: June 2022
Publisher : Surgical Residency Program Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jiscm.v2i1.25

Abstract

Introduction: Previous studies have shown the risky behavior that causes women’s vulnerability in markets to STI transmission is sexual intercourse with more than one partner. The present study reveals in depth risky sexual behavior and STI prevention among female merchants based on the behavioral theory of the Health Belief Model.  This study aims to determine the risky sexual behavior and prevention of STIs in female merchants based on the behavioral theory of health belief model. Methods: This study uses mix-methods (quantitative and qualitative methods). Using the quantitative method, this study first found a descriptive picture with a cross-sectional design. Then with the qualitative method, it extracted more in depth the experiences and social contexts experienced by the participants. The research sample was taken from 100 female merchants and in-depth interviews were conducted with 20 of those who had had sexual intercourse with an age range of 18-45 years in Denpasar City. Respondents were selected by purposive sampling. Results: Risky sexual behavior by most of the respondents is by having premarital sexual intercourse. Most of the respondents, which is 60%, in the market perceive such action would not risk getting an STI because of loyalty to their partner. In terms of the seriousness of STIs, they assume it is indeed a serious disease. Nevertheless, to prevent STIs, the respondents assure us that avoiding risky sexual behavior is not truly what matters. The respondents believe they can manage to afford not to engage in risky sexual behavior for the prevention of STIs. Conclusion: Most female merchants believe having risky sexual intercourse will not risk causing them to contract an STI. To overcome this, it is necessary to establish special programs to reduce the number of STIs in the community, especially in low-risk groups such as female merchants.

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