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Ophthalmologica Indonesiana
Published by Perhimpunan Dokter Spesialis Mata Indonesia
ISSN : 01261193     EISSN : 2460545X     DOI : 10.35749
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
Ophthalmologica Indonesiana is an open accessed online journal and comprehensive peer-reviewed ophthalmologist journal published by the Indonesian Ophthalmologist Association / Perhimpunan Dokter Spesialis Mata (PERDAMI). Our main mission is to encourage the important science in the clinical area of the ophthalmology field. We welcome authors for original articles (research), review articles, interesting case reports, special articles, clinical practices, and medical illustrations that focus on the clinical area of ophthalmology medicine.
Arjuna Subject : Kedokteran - Ophthalmology
Articles 13 Documents
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Search results for , issue "Vol 49 No 1 (2023): Ophthalmologica Indonesiana" : 13 Documents clear
Perkembangan Terkini Optic Neuritis syntia nusanti
Majalah Oftalmologi Indonesia Vol 49 No 1 (2023): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v49i1.100775

Abstract

EFFECT OF BLOOD GLUCOSE CONTROL TOWARDS PLASMA AND VITREOUS LEVELS OF VASCULAR ENDOTHELIAL GROWTH FACTOR AND PLACENTAL GROWTH FACTOR IN DIABETIC RATS Anggun Rama Yudantha; Nina Asrini Noor; Joedo Prihartono
Majalah Oftalmologi Indonesia Vol 49 No 1 (2023): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v49i1.100794

Abstract

Purpose: To compare plasma and vitreous level of vascular endothelial growth factor (VEGF) and placental growth factor (PlGF) in diabetic rats with poor blood glucose (BG) control, reconstitution of good BG control, and nondiabetic rats, and to investigate the effect of reconstitution of good BG control to VEGF and PlGF plasma and vitreous level. Methods: This is an experimental study using eighteen Sprague Dawley rats which were divided into intervention group (n=14) and control group (n=4). Intervention group were given Streptozotocin (STZ) injection to induce diabetes. After 4 weeks, intervention group was randomly divided into group I for termination and group II for reconstitution of good BG control with insulin for the following 4 weeks, and so was the control group. Plasma and vitreous samples were taken. VEGF and PlGF levels were evaluated with enzyme-linked immunosorbent assay (ELISA). Results: Seventeen of 18 rats survived in intervention group. BG level of intervention group II decreased dramatically to normoglycemia. ELISA at month 1 showed that VEGF vitreous level tend to be higher in intervention group I compared to control I, 196.36 ± 65.24 pg/dL and 123.64 ± 44.99, respectively (p=0.20). ELISA at month 2 showed that PlGF vitreous level of intervention group I were significantly higher compared to control I, 59.04 ± 2.48 and 51.93 ± 3.15, respectively (p=0.01). Vitreous and plasma VEGF of intervention group I and II were not different, while vitreous and plasma PlGF were significantly higher in group II. Conclusions: Vitreous levels of VEGF and PlGF were increased in diabetic rats compared to nondiabetic, and reconstitution of good BG control for 1 month were unable to reduce VEGF and PlGF levels.
COMPARISON OF SECONDARY AC-IOL IMPLANTATION ON APHAKIA PATIENTS WITHOUT CAPSULAR SUPPORT AFTER PARS PLANA VITRECTOMY VERSUS COMPLICATED CATARACT SURGERY Widya Ardhana Reswari; Prili Olda; Erin Arsianti; Elisa Manueke; Supanji Supanji
Majalah Oftalmologi Indonesia Vol 49 No 1 (2023): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v49i1.100796

Abstract

Introduction and objectiv: Capsular support is often absent in cases of aphakia secondary to ocular trauma or previous complicated intraocular surgery. This study aims to compare the short-term efficacy and safety of secondary AC IOL implantation for aphakia patients who underwent pars plana vitrectomy and complicated cataract surgery Method: Retrospective, comparative, case series of 72 aphakic eyes without capsular support after pars plana vitrectomy (Group 1 =37 eyes) and complicated cataract surgery (Group 2=35 eyes) who underwent secondary AC-IOL implantation (Iris Claw and Anterior Chamber) in Yap Eye Hospital and Air Force Central Hospital Hardjolukito. Basic characteristics such as age, sex, laterality, visual acuity, intraocular pressure (IOP), central corneal thickness, endothelial count, axial length, anterior chamber depth and keratometry were recorded Results: There were no statistically differences at baseline characteristics between the two groups. Despite the proportion difference of lens type used in both group (p=0.04), the mean visual acuity outcome at day 1 and month 3 were found similar. However, on day 7 and month 1 the difference of postoperative visual acuity showed a trend. The difference of postoperative mean IOP was also not significant at day 1, month 1 and month 3, but showed a trend in day 7 (p=0.06). The proportion of complication cases were found different in both group (p=0.01), with secondary glaucoma was found highest (18%). Conclusion: The outcomes of secondary anterior chamber IOL implantation after pars plana vitrectomy and complicated cataract surgery were found similar, although there was a significant difference in the proportion of complication in both groups

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