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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 10 Documents
 1 
Search results for , issue "Vol 18, No 02 (1986)" : 10 Documents clear
Peace and the medical profession R. Soewasono, R. Soewasono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 18, No 02 (1986)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (466.393 KB)

Abstract

This article described how nuclear weapons could pose a threat to the health and life of people. An all out nuclear war would destroy world civilization, and human existence itself would be imperiled. There could be no adequate medical response to a nuclear war; the only cure is prevention. Furthermore, this article pinpointed that all physicians should be aware of their responsibilities to give aid not just to the sick but to the billions of well living human beings who comprise the human species. The easiest way to shoulder this responsibility is by working to prevent nuclear war, because of their ethical commitment to protect the life and health of humankind. Finally, the teaching about nuclear weapons and nuclear war in medical schools is proposed. Key Words: peace - nuclear war - protection of humankind - medical profession - peace—oriented education
Displacement of bilirubin from human albumin by drugs Achmad Surjono, Achmad Surjono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 18, No 02 (1986)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (247.389 KB)

Abstract

The displacing effect of 18 commonly used drugs on bilirubin-albumin binding were studied quantitatively. The competitive results of certain concentrations of drugs were measured by peroxidase oxidation method on standard bilirubin-albumin solution (bilirubin 0.255 mmol, albumin 0.45 mmol. bil /alb 0.56). Sulfisoxazole, the known clinically potent bilirubin-displacer was used as control. The apparent binding constant to the high-affinity site of albumin (Kd) of mephenamate (1.4 X 105), indomethacin (1.23 X 105), diflunisal (8.4 X 104), diazepam (6.7 X 104) and furosemide (3 X 104) were stronger than sulfisoxazole (1.72 x 104). Latamoxef, aminophylline and cefalotin were slightly lower than sulfisoxazole. The maximal displacing factors (MDF) were also determined, whereas sulfisoxasole was 2.29. Taking the MDF 1.2 as the upper limit for significant danger of displacement, mephenamate (4.02), latamoxed (1.63) and diflunisal (1.24) showed a higher risks Moderate to slight risks of displacement were recorded on indomethacin, cevalotine, cefotaxime, acetyl salicylic acid, aminophylline, phenobarbital, furosemide and ampicillin. No possible bilirubin-displacer were shown by sulir. idac, diazepam, doxapzam, digoxin, amikacin, gentamicin and kanamycin. Caution and substitution should be considered in giving non-steroid and-inflammatory drugs for closure of patent ductus arteriosus and latamoxef for sepsis in premature infants because of their potential risk of bilirubin encephalopathy. Key Words: albumin-bilirubin-binding drugs - displacing effect - kernicterusanti-inflam matory drugs - bilirubin encephalopathy
Eyelid reconstruction after extirpation of lid tumor
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 18, No 02 (1986)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (236.06 KB)

Abstract

Extirpation of eyelid benign tumor, while the vision is still good, must be followed by lid reconstruction to protect the eyeball. The means of such reconstruction to make the lid function are optimal. A case of lid reconstruction after lid benign tumor extirpation with the remain of skin and the orbicular oculi muscle has been reported. The reconstruction was carried out by replacing the lost tarsoconjunctival tissue with the opposite tarsoconjuncdval tissue. The blepharoraphy was maintained until the cicatrical tissue formation was completed. Key Words: lid tumor extirpation - reconstruction of superior levator palpebral muscle - replacement of tarsoconjunctival tissue - blepharoraphy - ophthalmic surgery
Obstetric care and the prevention of blindness Soeprono, Soeprono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 18, No 02 (1986)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (470.907 KB)

Abstract

Blindness, affecting multidimensionally the lives of the individual, his family and the society, has been known according to the 1980 Indonesian Population Census to prevail for 22.1% with children and for 77.9% with adults. Based on this fact, causative factors as genetic aberrations, infectious diseases and malnutrition, drugs and radiation, birth traumas and hypertensive diseases ought to be eliminated by all possible measures, e. g. adequate obstetric care starting from the pre-conceptional period, during pregnancy, delivery and in early childhood, by a more healthy pattern of living and nutrition, and a bigger sense of responsibility on the part of both parents. It is thought to be appropriate to base laws and regulations governing social, medical and educational rehabilitation and aid programs on more Adequate medical and functional criteria to better benefit the visually handicapped. Key Words: blindness - obstetric care - genetic diseases - malnutrition - congenital disorders
Trends in the development of medical science and technology at the beginning of the 21s1 century T. Jacob, T. Jacob
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 18, No 02 (1986)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (328.81 KB)

Abstract

Mau is the only creature that could think about his future, and therefore, prepares for it and actually shapes it, or even invents his future. Predictions about the future are more relevant nowadays because of the importance of intergenerational justice, of learning from history and of adaptational preparation in view of rapid technological changes. Scientific and technological development will unavoidably influence the course of medical sciences and practice. The sociocultural impact of this development will affect even the essence of life itself, not only the human society, food strategy, demography, disease pattern, and environment. Most important is the impact on ethics and religion, creating frustration, uncertainties, emptiness and insecurity in life which consequently demands the revival of both and assure their existence in the next century. It is suggested that scientific ethics will be intensified, religious interpretations adjusted to the development of civilization without deviating from its basic principles, and that a new paradigm in medicine is needed in order to restore the disequilibrium brought forth by the culture of overconsumption and overcompetition. Key Words: futuristics - medical sciences - technological impact = ethics - religion
Obstetric care and the prevention of blindness Soeprono Soeprono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 18, No 02 (1986)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (470.907 KB)

Abstract

Blindness, affecting multidimensionally the lives of the individual, his family and the society, has been known according to the 1980 Indonesian Population Census to prevail for 22.1% with children and for 77.9% with adults. Based on this fact, causative factors as genetic aberrations, infectious diseases and malnutrition, drugs and radiation, birth traumas and hypertensive diseases ought to be eliminated by all possible measures, e. g. adequate obstetric care starting from the pre-conceptional period, during pregnancy, delivery and in early childhood, by a more healthy pattern of living and nutrition, and a bigger sense of responsibility on the part of both parents. It is thought to be appropriate to base laws and regulations governing social, medical and educational rehabilitation and aid programs on more Adequate medical and functional criteria to better benefit the visually handicapped. Key Words: blindness - obstetric care - genetic diseases - malnutrition - congenital disorders
Eyelid reconstruction after extirpation of lid tumor Mu'tasimbillah Ghozi Mu'tasimbillah Ghozi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 18, No 02 (1986)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (236.06 KB)

Abstract

Extirpation of eyelid benign tumor, while the vision is still good, must be followed by lid reconstruction to protect the eyeball. The means of such reconstruction to make the lid function are optimal. A case of lid reconstruction after lid benign tumor extirpation with the remain of skin and the orbicular oculi muscle has been reported. The reconstruction was carried out by replacing the lost tarsoconjunctival tissue with the opposite tarsoconjuncdval tissue. The blepharoraphy was maintained until the cicatrical tissue formation was completed. Key Words: lid tumor extirpation - reconstruction of superior levator palpebral muscle - replacement of tarsoconjunctival tissue - blepharoraphy - ophthalmic surgery
Peace and the medical profession R. Soewasono R. Soewasono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 18, No 02 (1986)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (466.393 KB)

Abstract

This article described how nuclear weapons could pose a threat to the health and life of people. An all out nuclear war would destroy world civilization, and human existence itself would be imperiled. There could be no adequate medical response to a nuclear war; the only cure is prevention. Furthermore, this article pinpointed that all physicians should be aware of their responsibilities to give aid not just to the sick but to the billions of well living human beings who comprise the human species. The easiest way to shoulder this responsibility is by working to prevent nuclear war, because of their ethical commitment to protect the life and health of humankind. Finally, the teaching about nuclear weapons and nuclear war in medical schools is proposed. Key Words: peace - nuclear war - protection of humankind - medical profession - peace—oriented education
Trends in the development of medical science and technology at the beginning of the 21s1 century T. Jacob T. Jacob
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 18, No 02 (1986)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (328.81 KB)

Abstract

Mau is the only creature that could think about his future, and therefore, prepares for it and actually shapes it, or even invents his future. Predictions about the future are more relevant nowadays because of the importance of intergenerational justice, of learning from history and of adaptational preparation in view of rapid technological changes. Scientific and technological development will unavoidably influence the course of medical sciences and practice. The sociocultural impact of this development will affect even the essence of life itself, not only the human society, food strategy, demography, disease pattern, and environment. Most important is the impact on ethics and religion, creating frustration, uncertainties, emptiness and insecurity in life which consequently demands the revival of both and assure their existence in the next century. It is suggested that scientific ethics will be intensified, religious interpretations adjusted to the development of civilization without deviating from its basic principles, and that a new paradigm in medicine is needed in order to restore the disequilibrium brought forth by the culture of overconsumption and overcompetition. Key Words: futuristics - medical sciences - technological impact = ethics - religion
Displacement of bilirubin from human albumin by drugs Achmad Surjono Achmad Surjono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 18, No 02 (1986)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (247.389 KB)

Abstract

The displacing effect of 18 commonly used drugs on bilirubin-albumin binding were studied quantitatively. The competitive results of certain concentrations of drugs were measured by peroxidase oxidation method on standard bilirubin-albumin solution (bilirubin 0.255 mmol, albumin 0.45 mmol. bil /alb 0.56). Sulfisoxazole, the known clinically potent bilirubin-displacer was used as control. The apparent binding constant to the high-affinity site of albumin (Kd) of mephenamate (1.4 X 105), 'indomethacin (1.23 X 105), diflunisal (8.4 X 104), diazepam (6.7 X 104) and furosemide (3 X 104) were stronger than sulfisoxazole (1.72 x 104). Latamoxef, aminophylline and cefalotin were slightly lower than sulfisoxazole. The maximal displacing factors (MDF) were also determined, whereas sulfisoxasole was 2.29. Taking the MDF 1.2 as the upper limit for significant danger of displacement, mephenamate (4.02), latamoxed (1.63) and diflunisal (1.24) showed a higher risks Moderate to slight risks of displacement were recorded on indomethacin, cevalotine, cefotaxime, acetyl salicylic acid, aminophylline, phenobarbital, furosemide and ampicillin. No possible bilirubin-displacer were shown by sulir. idac, diazepam, doxapzam, digoxin, amikacin, gentamicin and kanamycin. Caution and substitution should be considered in giving non-steroid and-inflammatory drugs for closure of patent ductus arteriosus and latamoxef for sepsis in premature infants because of their potential risk of bilirubin encephalopathy. Key Words: albumin-bilirubin-binding drugs - displacing effect - kernicterusanti-inflam matory drugs - bilirubin encephalopathy

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