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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 8 Documents
 1 
Search results for , issue "Vol 21, No 03 (1989)" : 8 Documents clear
Pengaruh Sistemik Obat Tetes Mata. Pengaruh Tetes Mata Maleat Timolol Terhadap Tekanan Darah dan Detak Nadi Tanpa Beban: Penelidan Pendahuluan
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 21, No 03 (1989)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (144.351 KB)

Abstract

Timolol maleat, a new beta-adrenergic blocking agent, lowers intraocular pressure by decreasing actuous productiOri. It available in 0.25%;and 0.50% solution as an eye drop. The systemic effect of the timolol maleat 0.26% eye drops were observed among healthy medical students: The pulse rate and systolic blood pressure were insignificantly decreased but diastolic blood pressure was, insignificantly increased.Key Words: timolol maleat -- beta-adrenergic blocking agents -- blood pressure -- pulse rate -- intraocular pressure
Toksoplasmosis pada Wanita Hamil Risanto Siswosudarmo, Risanto Siswosudarmo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 21, No 03 (1989)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (432.93 KB)

Abstract

A literature review of toxoplasmosis in pregnant women has been carried out. The airn..of this review is.to recognize the epidemiology, pathogenesis, mode of transmission, clinical manifestation, diagnosis and mariagernent. Toxoplasrnosis is a parasitic disease catiiedby ToxoplasinO gondii. Two groups of people being higly VuLnerable to the disease are the deieloping fetus and thoseWhO are inimtmodeficient. In humans, prevalence of positive serologic test titers increases with age. There are considerable differences in prevalence rate between, countries.. The prevalence rate of positive serologic test among pregnant women varies between 15% to 96% depending on the geographic area and age group, while the incidence of congenital toxoplasmosis varies from one to seven per 1000 live births.Toxoplasma invade every organ in the body; but the most vulnerable organ or tissue are those where access to circulating antibody is.impeded (e.g., brain and retina). The barrier to passive diffusiOn Of antibodies into brain and eye has been given as an explanatiOn of the continued proliferation of theparasite on theie sites at the same time that his disappearing from eirtraneural sites, giving rise to latent infection. The developing fetus is usually infected transplacentally. The risk of fetal infection is related to the time when maternal infection occurs. if Toxoplasma infection is acquired late in pregnancy, the protozoa are most frequently transmitted to the fetus but the infection is subclinical in the newborn. If, however, the mother is infected early in pregnancy (for example-during the third month) transmission to the fetus occurs less often but frequently results in severe disease to the new born. There is no clinical signs and symptoms pathognomonic for the disease in pregnant women. In the infant, there is usually a clinical triad — hydrocephalus, chorioretinitis and intracranial calcifications. However, definitive diagnosis of Toxoplasma infection is established by isolation of Toxoplasma gondii from blood or body fluid.,deniostration of cyst in the placenta or tissues or by serologic tests. Sulfonamides, pyrimethamine and spiramycine are drugs considered tole effective in killing the organism. Seronegative pregnant women is .the group of people in which avoidance of infectionKey Words: Toxoplasma gondii --pregnancy --congenital toxoplasmosis serologic test -- pyrimethamine
Patogenesis Diabetes Mellitus Tidak Bergantung Insulin (Non-/fain/in Dependent Diabetes Mellitus) Ahmad H. Asdie, Ahmad H. Asdie
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 21, No 03 (1989)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (312.95 KB)

Abstract

The paper described a Short review of mechanism of glucose intolerance in most non-innilin dependent diabetics which is now clear that is not caused by defect in insulin secretion.alone. Genetic predisposition, impaired glucose-mediated insulin secretion, excessive basal hepatiC gluciase production (HGP) and cellular resistance to insulin action have been docuthented in NIDDM:The increase in basal HGP is the primary factor responsible for fasting hyperglycemia, where as both insulin resistance in peripheral tissues and relative defective insulin secretion contribute to the impaired glucose disposal following oral or intravenous glucose administration. Both receptor and post-receptor defects contribute to the insulin resistance observed in non-insulin dependent diabetic patients.The heterogeneity of NIDDM may present as insulin "resistant or insulin sensitive variety:Key Words: NIDDM -- insulin secretion --hepatic glucose produCtion -- insulin resistance type -- insulin sensitive type,
Bom Atom di Atas Hiroshima) Suatu Pengalaman Nyata Arifin Bey, Arifin Bey
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 21, No 03 (1989)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (454.604 KB)

Abstract

The author was one of the students from occupied territories in South East Asia studying in Hiroshima when the city was atomic bombed in 1945. Tokyo was carpet-bombed in 1944-45 and foreign students were spread to other relatively safe cities. Before August 1945 Hiroshima was never bombed, but air raid alarms sounded every morning. On August 6 after the alarm was cleared the author saw a "lightning" flashed through a classroom window, and the school building, 2 km from the hypocenter, suddenly crashed, After being unconscious for a while, he noticed that the sunny morning has turned into darkness.Outside, people were running in fear and aimlessly. Some showed bleeding and others had their clothes torn or burnt. The skin of quite a few people was torn off and hanging loosely like gloves. Everything in sight was flattened to the earth and some carts were on fire. The river was full with rafts and evacuating people. Many immersed themselves in the water to alleviate the extreme heat and repetitively asked for water to drink. Most people had no clothes any more and their skin ap• Reared red.Numerous people were walking among the dying and dead bodies looking for their relatives and friends. Identification was difficult due to the damaged face and decaying bodies. It took days to dispose the dead bodies by trucks. Ten days after the bombing, the students were brought to Tokyo, and here blood tests disclosed that some suffered from leucopenia. A Malayan student died in Kyoto during the trip to Tokyo.Key Words: atomic bomb-- Hiroshima -- medical effects of nuclear war -- thermal radiation -- shock wave
Pengaruh Sistemik Obat Tetes Mata. Pengaruh Tetes Mata Maleat Timolol Terhadap Tekanan Darah dan Detak Nadi Tanpa Beban: Penelidan Pendahuluan Mu'tasimbillah Ghozi Mu'tasimbillah Ghozi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 21, No 03 (1989)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (144.351 KB)

Abstract

Timolol maleat, a new beta-adrenergic blocking agent, lowers intraocular pressure by decreasing actuous productiOri. It available in 0.25%;and 0.50% solution as an eye drop. The systemic effect of the timolol maleat 0.26% eye drops were observed among healthy medical students: The pulse rate and systolic blood pressure were insignificantly decreased but diastolic blood pressure was, insignificantly increased.Key Words: timolol maleat -- beta-adrenergic blocking agents -- blood pressure -- pulse rate -- intraocular pressure
Patogenesis Diabetes Mellitus Tidak Bergantung Insulin (Non-/fain/in Dependent Diabetes Mellitus) Ahmad H. Asdie Ahmad H. Asdie
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 21, No 03 (1989)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (312.95 KB)

Abstract

The paper described a Short review of mechanism of glucose intolerance in most non-innilin dependent diabetics which is now clear that is not caused by defect in insulin secretion.alone. Genetic predisposition, impaired glucose-mediated insulin secretion, excessive basal hepatiC gluciase production (HGP) and cellular resistance to insulin action have been docuthented in NIDDM:The increase in basal HGP is the primary factor responsible for fasting hyperglycemia, where as both insulin resistance in peripheral tissues and relative defective insulin secretion contribute to the impaired glucose disposal following oral or intravenous glucose administration. Both receptor and post-receptor defects contribute to the insulin resistance observed in non-insulin dependent diabetic patients.The heterogeneity' of NIDDM may present as insulin "resistant or insulin sensitive variety:Key Words: NIDDM -- insulin secretion --hepatic glucose produCtion -- insulin resistance type -- insulin sensitive type,
Bom Atom di Atas Hiroshima) Suatu Pengalaman Nyata Arifin Bey Arifin Bey
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 21, No 03 (1989)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (454.604 KB)

Abstract

The author was one of the students from occupied territories in South East Asia studying in Hiroshima when the city was atomic bombed in 1945. Tokyo was carpet-bombed in 1944-45 and foreign students were spread to other relatively safe cities. Before August 1945 Hiroshima was never bombed, but air raid alarms sounded every morning. On August 6 after the alarm was cleared the author saw a "lightning" flashed through a classroom window, and the school building, 2 km from the hypocenter, suddenly crashed, After being unconscious for a while, he noticed that the sunny morning has turned into darkness.Outside, people were running in fear and aimlessly. Some showed bleeding and others had their clothes torn or burnt. The skin of quite a few people was torn off and hanging loosely like gloves. Everything in sight was flattened to the earth and some carts were on fire. The river was full with rafts and evacuating people. Many immersed themselves in the water to alleviate the extreme heat and repetitively asked for water to drink. Most people had no clothes any more and their skin ap• Reared red.Numerous people were walking among the dying and dead bodies looking for their relatives and friends. Identification was difficult due to the damaged face and decaying bodies. It took days to dispose the dead bodies by trucks. Ten days after the bombing, the students were brought to Tokyo, and here blood tests disclosed that some suffered from leucopenia. A Malayan student died in Kyoto during the trip to Tokyo.Key Words: atomic bomb-- Hiroshima -- medical effects of nuclear war -- thermal radiation -- shock wave
Toksoplasmosis pada Wanita Hamil Risanto Siswosudarmo Risanto Siswosudarmo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 21, No 03 (1989)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (432.93 KB)

Abstract

A literature review of toxoplasmosis in pregnant women has been carried out. 'The airn..of this review is.to recognize the epidemiology, pathogenesis, mode of transmission, clinical manifestation, diagnosis and mariagernent. Toxoplasrnosis is a parasitic disease catiied'by ToxoplasinO gondii. Two groups 'of people being higly VuLnerable to the disease are 'the deieloping fetus and those'WhO are inimtmodeficient. In humans, prevalence of positive serologic test titers increases with age. There are considerable differences in prevalence rate between, countries.. The prevalence rate of positive serologic test among pregnant women varies between 15% to 96% depending on the geographic area and age group, while the incidence of congenital toxoplasmosis varies from one to seven per 1000 live births.Toxoplasma invade every organ in the body; but the most vulnerable organ or tissue are those where access to circulating antibody is.impeded (e.g., brain and retina). The barrier to passive diffusiOn Of antibodies into brain and eye has been given as an explanatiOn of the continued proliferation of the'parasite on theie sites at the same time that his disappearing from eirtraneural sites, giving rise to latent infection. The developing fetus is usually infected transplacentally. The risk of fetal infection is related to the time when maternal infection occurs. if Toxoplasma infection is acquired late in pregnancy, the protozoa are most frequently transmitted to the fetus but the infection is subclinical in the newborn. If, however, the mother is infected early in pregnancy (for example-during the third month) transmission to the fetus occurs less often but frequently results in severe disease to the new born. There is no clinical signs and symptoms pathognomonic for the disease in pregnant women. In the infant, there is usually a clinical triad — hydrocephalus, chorioretinitis and intracranial calcifications. However, definitive diagnosis of Toxoplasma infection is established by isolation of Toxoplasma gondii from blood or body fluid.,deniostration of cyst in the placenta or tissues or by serologic tests. Sulfonamides, pyrimethamine and spiramycine are drugs considered tole effective in killing the organism. Seronegative pregnant women is .the group of people in which avoidance of infectionKey Words: Toxoplasma gondii --pregnancy --congenital toxoplasmosis serologic test -- pyrimethamine

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