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All Journal Klinikal Sains (Jurnal Analis Kesehatan) Husada Mahakam: Jurnal Kesehatan
Nurul Anggrieni
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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AKTIVITAS DAN EFEKTIVITAS ANTIBAKTERI EKSTRAK DAUN CIPLUKAN (Physalis angulata L.) TERHADAP PERTUMBUHAN Bacillus cereus Tiara Dini Harlita; Nurul Anggrieni; Ardiana Finda Widya Rahmawati
Husada Mahakam Vol 9 No 2 (2019): Nopember 2019
Publisher : Poltekkes Kemenkes Kalimantan Timur (URL: http://poltekkes-kaltim.ac.id/)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (333.846 KB) | DOI: 10.35963/hmjk.v5i1.166

Abstract

Ciplukan leaf (Physalis angulata L.) is one of the plants used by the community as an alternative to avoid side effects of antibiotics. This plant has traditionally been used to cure various diseases. Potential leaf ciplukan as medicinal plants suspected due to the active compounds active ingredients contained in it. This study aims to test the activity and effectiveness of the antibacterial ethanol extract of ciplukan leaf on the growth of Bacillus cereus. Ciplukan leaf were extracted by maceration method using ethanol 96%. Each concentration was tested for antibacterial activity against B.cereus using disc diffusion method. The determination of minimum inhibitory concentrations by solid dilution. Data were analyzed with ANOVA at 95% confidence level. The test results showed that ciplukan leaf ethanol extract (P. angulata L.) had activity and effectiveness on B. cereus growth in vitro. The most effective concentration of ciplukan leaf ethanol extract can inhibit the growth of B. cereus is 30 mg/mL with inhibit zone of 24.2 mm. The minimum inhibitory concentration of ciplukan leaf ethanol extract on B. cereus growth was 5 mg/mL.
HUBUNGAN KADAR KREATININ DAN MIKROALBUMIN PADA PASIEN DIABETES MELLITUS TIDAK TERKONTROL DI KLINIK MEDIA FARMA SAMARINDA Suryanata Kesuma; Nurul Anggrieni; Nurul Alidasyah
Klinikal Sains : Jurnal Analis Kesehatan Vol 10 No 2 (2022): Desember
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikal_sains.v10i2.2695

Abstract

Diabetes Mellitus (DM) is a non-communicable disease but is a fairly large health problem in Indonesia today. The HbA1C examination is the gold standard in measuring glycemic levels, while the examination of creatinine and microalbumin levels is one of the parameters used to assess kidney function or diabetic nephropathy. This study aims to determine the relationship between creatinine levels and microalbumin levels in patients with uncontrolled diabetes mellitus at the Media Farma Samarinda Clinic. This study used a cross-sectional design using the Spearman correlation test. The samples in this study were 107 samples with HbA1C levels > 7%. The sampling technique was carried out using quota sampling. The variables measured were levels of HbA1C, creatinine, and microalbumin. The results of this study indicate that the value of p = (0.589) > = (0.05) in the correlation of HbA1C > 7% with creatinine and the value of p = (0.085) > = (0.05) in the correlation of HbA1C > 7% with microalbumin and the value of p = (0.032) > (0.05) on the correlation of creatinine with microalbumin so that H0 is accepted and Ha is rejected. Based on the results of this study, it can be concluded that there is no relationship between creatinine and microalbumin levels in patients with uncontrolled diabetes mellitus at the Media Farma Samarinda Clinic.
Co-Authors Ardiana Finda Widya Rahmawati Nurul Alidasyah Suryanata Kesuma Tiara Dini Harlita