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All Journal Klinikal Sains (Jurnal Analis Kesehatan) Husada Mahakam: Jurnal Kesehatan
Suryanata Kesuma
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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HUBUNGAN KADAR KREATININ DAN MIKROALBUMIN PADA PASIEN DIABETES MELLITUS TIDAK TERKONTROL DI KLINIK MEDIA FARMA SAMARINDA Suryanata Kesuma; Nurul Anggrieni; Nurul Alidasyah
Klinikal Sains : Jurnal Analis Kesehatan Vol 10 No 2 (2022): Desember
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikal_sains.v10i2.2695

Abstract

Diabetes Mellitus (DM) is a non-communicable disease but is a fairly large health problem in Indonesia today. The HbA1C examination is the gold standard in measuring glycemic levels, while the examination of creatinine and microalbumin levels is one of the parameters used to assess kidney function or diabetic nephropathy. This study aims to determine the relationship between creatinine levels and microalbumin levels in patients with uncontrolled diabetes mellitus at the Media Farma Samarinda Clinic. This study used a cross-sectional design using the Spearman correlation test. The samples in this study were 107 samples with HbA1C levels > 7%. The sampling technique was carried out using quota sampling. The variables measured were levels of HbA1C, creatinine, and microalbumin. The results of this study indicate that the value of p = (0.589) > = (0.05) in the correlation of HbA1C > 7% with creatinine and the value of p = (0.085) > = (0.05) in the correlation of HbA1C > 7% with microalbumin and the value of p = (0.032) > (0.05) on the correlation of creatinine with microalbumin so that H0 is accepted and Ha is rejected. Based on the results of this study, it can be concluded that there is no relationship between creatinine and microalbumin levels in patients with uncontrolled diabetes mellitus at the Media Farma Samarinda Clinic.
UJI DAYA HAMBAT CACING TANAH (Lumbricus rubellus) TERHADAP PERTUMBUHAN BAKTERI Salmonella typhi SECARA IN VITRO Suryanata Kesuma; Lamri Lamri; Marezha Aulia Putri Sugiarsono
Husada Mahakam Vol 12 No 2 (2022): November 2022
Publisher : Poltekkes Kemenkes Kalimantan Timur (URL: http://poltekkes-kaltim.ac.id/)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35963/hmjk.v12i2.324

Abstract

One of the pathogenic microbes that often infect humans is Salmonella typhi which causes typhoid fever. Antibiotics are the main choice in treating typhoid fever. Herbal ingredients are very safe for humans because they contain active compounds as effective antiseptics. In the modern world today, the active compound lumbricin in earthworms (Lumbricus rubellus) is used as a medicinal ingredient. The purpose of the study was to determine the diameter of the inhibition zone and to determine the effectiveness of the inhibition of earthworm powder (Lumbricus rubellus) with concentrations of 25%, 50%, and 100% against the growth of Salmonella typhi bacteria. This type of research is a laboratory experiment. Earthworm (Lumbricus rubellus) is processed into powder by roasting technique, then made in the form of a medicinal disc. Earthworm powder was tested for sensitivity by disc diffusion method in concentrations of 25%, 50%, and 100% against the growth of Salmonella typhi, which was cultured in Muller Hinton Agar media with a clear zone formed for 24 hours. The study results were carried out with seven repetitions at a concentration of 25% no antibacterial power and antibacterial effectiveness. However, at concentrations of 50% and 100%, the average diameter of the inhibition zones was 0.21 mm and 0.92 mm, and the antibacterial efficacy was 0.7% and 3.4%, respectively. This study concludes is that at a minimum concentration of 50%, antibacterial power and effectiveness were obtained.
PENGARUH VARIASI WAKTU PENYIMPANAN TERHADAP STABILITAS REAGEN KERJA PADA HASIL PEMERIKSAAN KADAR KREATININ Silvi Marshela; Suryanata Kesuma; Suparno Putera Makkadafi
Klinikal Sains : Jurnal Analis Kesehatan Vol 11 No 2 (2023): Desember
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikal_sains.v11i2.3809

Abstract

Kidney is one of the organs of the body whose role is very important to maintain the stability of volume, osmolarity of extracellular fluid, and electrolyte composition. One of the parameters to determine kidney function that is usually done is creatinine examination. Preparation of working reagents is very important for accurate results in an examination. The purpose of this study was to determine the effect of storage on the stability of working reagents on creatinine examination. This type of research is a pseudo-experiment, to determine the difference between working reagents that are directly used with working reagents that are stored for several days. The research variables are the length of storage of work reagents, creatinine levels and storage temperature. The sample used in this study was normal creatinine control. The results were analyzed using Microsoft Excel and using the Kruskal Wallis Non Parametric test. The results of the study showed that the average reagent immediately and 5 days was 0.8 mg/dl and at 8 days 1.2 mg/dl, the accuracy obtained was -3.2% and 0.4%, the precision value obtained was 35.1% and 31.0%, in statistical tests significant results <0.05, meaning that there are differences in the results of examinations using working reagents that are used immediately and those stored for 5 and 8 days.
Co-Authors Lamri Lamri Marezha Aulia Putri Sugiarsono Nurul Alidasyah Nurul Anggrieni Silvi Marshela Suparno Putera Makkadafi