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Acta Medical and Health Sciences (AMHS)
Published by Universitas Jenderal Achmad Yani
ISSN : 28305531     EISSN : 28305426     DOI : https://doi.org/10.35990
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Acta Medical and Health Sciences (AMHS) is a scientific journal that publishes research articles, case reports, literature reviews, and other topics relevant to the field of medicine and health, either clinically or to the biomolecular level. Manuscript under consideration that may be uploaded is a full text of article which has not been published in other national magazines. AMHS is published three times a year (every February, June, and October).
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 30 Documents
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Cardiac damage in an adolescent patient with COVID-19: a case report Prihati Pujowaskito; Tamia S Tartila; Novaro A Tafriend; Fatimah D K Jannah; Elsy Mayasari
ACTA Medical Health Sciences Vol. 1 No. 2 (2022): ACTA Medical Health Sciences
Publisher : ACTA Medical Health Sciences

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Abstract

COVID-19 has been found to affect the cardiovascular system leading to myocardial damage.A study of 41 patients in Wuhan, China, found that 12% of COVID-19 patients experiencedvirus-related acute cardiac damage.Subsequent bigger Chinese studies also found acute cardiacdamage in 7.2% to 27.8% of hospitalized patients. As a chronicsequela, this condition mayresult in cardiomyopathy. We report acase of an adolescent COVID-19 survivor with dilatedcardiomyopathy with no underlying heart disease. A male patient aged 16 years old wasadmitted to our outpatient clinic with the primary symptom of exhaustion and had recoveredfrommild to moderate COVID-19 one month prior to the visit. No previous history of heartdisease was documented. Physical examination showed no abnormalities. Laboratory resultsrevealed substantially elevated NT-proBNP (7705 pg/mL) and D-dimer (1850 ng/mL). ECGpresented normal sinus rhythm with poorR wave progression. Echocardiography revealed allchamber dilatation, eccentric left ventricular hypertrophy, globalhypokinetic, moderate mitralregurgitation, and reduced ejection fraction (22%). We diagnosed the patient with new-onsetdilated cardiomyopathy and began treatment with candesartan, bisoprolol, furosemide,spironolactone, rivaroxaban, and trimetazidine. The recovery was steady at three-monthfollow-up visit. The emergence of new-onset cardiomyopathy in this previously healthyadolescent raisesthepossibility of COVID-19 acting asthe sole cause of myocardial injuryin theabsence of underlying heart disease. To avoid further complications, comprehensive evaluationand effective therapy should be implemented during hospitalization and post-discharge.Additional tests such as cardiac magnetic resonance imaging and endomyocardial biopsiesshouldbe performed to support final proof.   DOI : 10.35990/amhs.v1n2.p88-96
Description of injury to the victim of motorcycle traffic accident Andri A Rusman; Livaldi N Aflah; Andri A Kusuma
ACTA Medical Health Sciences Vol. 1 No. 2 (2022): ACTA Medical Health Sciences
Publisher : ACTA Medical Health Sciences

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Abstract

Road accidents are events that can lead to injury or death. The number of fatalities from trafficaccidents is the eighth highest in the world. In Southeast Asia, up to 316,000 people die eachyear in road accidents. Motorcycles are the type of vehicle with the highest number of accidentscompared to other types of vehicles. The increase in motorcycle purchases in Indonesia isassociated with an increase in road accidents. Road accident injuries can occur on multiple partsof the body and can cause different types of injuries. The purpose of this study is to determinethe description of the victims of motorcycle traffic accidents in Southeast Asia. This researchis a descriptive study using literature study method by searching various literature that useselectronic databases such as Google Scholar, ResearchGate, PubMed, NCBI, WHO, Ministryof Health, ScienceDirect, and Springer to search related literature. Keywords used whensearching for items are injuries, car accidents, motorcycles, and Southeast Asian descriptions.A total of seven articles were selected for analysis using synthetic matrices, and the resultsshowed that working-age and male gender were most frequently involved in motorcycle roadaccidents. Extremities injuries are the most common site of injury and the majority of injuriesobtained are soft tissue injuries. In order to add data on the most common types of injuries tomotorcycle traffic accident victims in Indonesia, this study needs to be further conducted inIndonesia on the most common types of injuries to motorcycle traffic accident victims.   DOI : 10.35990/amhs.v1n2.p97-104
Relationship between backpack weight and incidence of low back pain in senior high students Daswara Djajasasmita; Zacarja Jacob Manoe; Feby Wulandari
ACTA Medical Health Sciences Vol. 1 No. 3 (2023): ACTA Medical Health Sciences
Publisher : ACTA Medical Health Sciences

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Abstract

Low back pain (LBP) is one of the most common musculoskeletal disorders that can impair daily activities. The causes of LBP are mostly non-specific, including the abnormalities in the soft tissues or form of muscles, ligament injuries, and muscle spasms or fat igue. One of the causes of LBP is carrying excess weight. If the load carried exceeds 15% of body weight, the person who carried the weight will experience musculoskeletal disorders. Students may carry a backpack with a weight that exceeds the recommended weight and this weight will put pressures on the muscles, ligaments, and tendons, causing tension and acute neck pain. These students then will have a higher risk of suffering LBP. The aimed of this study was to identify the relationship between the backpack load and the incidence of low back pain in students. Using the cross-sectional analytical method, this study was performed on a total of 63 students from a senior high school in Cimahi, Indonesia. Subjects were selected using the multistage random sampling and data on the sociodemographic, backpack load, and low back pain were collected and analyzed using the chi-square test. Results showed that 45 students (71.4%) experienced LBP, while the average weight of the backpack carried by these students 6.59 kg (p <0.001). Thus, there is a significant relationship between the excessive backpack weight and the incidence of LBP among students.   DOI : 10.35990/amhs.v1n3.p105-111
Development of a novel diagnostic kit candidate to detect dengue antibody, using IgY and protein a positive Staphylococcus aureus Eka Noneng Nawangsih; Lia Siti Halimah; Euis Reni Yuslianti; Sayu Putu Yuni Paryati
ACTA Medical Health Sciences Vol. 1 No. 3 (2023): ACTA Medical Health Sciences
Publisher : ACTA Medical Health Sciences

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Abstract

Early diagnosis of dengue hemorrhagic fever (DHF) is very important in determining further management. Diagnostic kits are intended as relatively faster, easier, and cheaper diagnostic tools. The objectives of this experimental laboratory study was to prepare a diagnostic kit candidate to detect dengue antibody in human serum using co -agglutination methods by utilizing protein A positive Staphylococcus aureus as a carrier to bind Fc immunoglobulin fractions without altering its ability to bind antigen. To enhance the sensitivity and specificity of the diagnostic kit, chicken IgY was used as one of the components. Rabbit immunoglobulin chicken anti-IgY was used as an intermediary connection between protein A positive and Staphylococcus aureus with chicken IgY. Solution A contains Staphylococcus aureus Cowan I and rabbit immunoglobulin chicken anti-IgY serum while Solution B contains anti-dengue chicken serum and dengue antigen. The laboratory experiments produced a formula of A: B = 1~3: 1~3 (v/v), which was then tested to human serum and compared with IgM and IgG ELISA tests as the gold standard. Data on the results of the test were statistically analyzed using chi - square test. Of the 65 qualified samples used, 47.69% resulted in true positive and 41.54% resulted in true negative. Meanwhile, the remaining samples demonstrated false negative (6.15%), positive predictive value (91.2%) and negative predictive value (87.1%). The sensitivity and specificity were 89% and 90%, respectively, with no significant diffe rences (p>0.05). Therefore, co-agglutination method using S. aureus with protein A positive as a carrier can be proposed as a diagnostic kit candidate to detect human serum dengue antibody to screen dengue hemorrhagic fever cases.   DOI : 10.35990/amhs.v1n3.p112-120
The effect of celery ethanol extract (Apium graveolens l.) against fatty liver in rat model of hyperlipidemia Indarti Trimurtini; Astri Pradini; Vania Vita Nirmala Sari; Evi Sovia
ACTA Medical Health Sciences Vol. 1 No. 3 (2023): ACTA Medical Health Sciences
Publisher : ACTA Medical Health Sciences

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Abstract

Fatty liver is a disorder of liver characterized by the accumulation of fat liver cells. The incidence of fatty liver in Indonesia is 30%. Fatty liver can be caused by hyperlipidemia. Hyperlipidemia triggers an increase of oxidative stress that leads to fatty liver. Treatment is usually carried out using statins, but long-term consumption of statin may lead to several side effects. Other treatment that can lower cholesterol levels traditionally is celery. This study aimed to determine the effect of ethanol extract of celery on the microscopic appearance of the liver induced by hypercholesterolemia in experimental rats. This was an posttest control group experimental on 25 rats that were divided into 5 groups: negative control group, positive control group, and three (3) treatment groups. Each treatment group was given a high-fat diet for 14 days, followed by a provision of high-fat diet with different celery extract doses of 37.5 mg/KgBW/day, 75 mg/KgBW/day, and 150 mg/KgBW/day. After the treatment completed, the rats were sacrificed and dissected, and their liver was for histopathological preparations. Data on the in the average fat score between the control group and the three treatment groups were collected and analyzed using one way ANOVA if they were normally distributed with the Kruskal Wallis test as the alternative test. To determine whether there was a significant difference between two treatment groups, a post-hoc statistical test was performed. A significant change was observed in the histological presentations of the liver between control and treatment groups (p <0.5). There was a marked improvement of cytoplasm, sinusoid and cell nucleus in the treatment groups compared to positive control group with a dose of 37.5 mg/KgBW/day as the most effective celery ethanol extract to improve liver fat due to fat accumulation.   DOI : 10.35990/amhs.v1n3.p121-127
The Comparison between Spinal Anesthesia Bupivacaine and Sevoflurane Anesthesia for Cesarean Section on Apgar Score Tatang Bisri; Elly Noer Rochmah; Arief Kurniawan; Angela Stella
ACTA Medical Health Sciences Vol. 1 No. 3 (2023): ACTA Medical Health Sciences
Publisher : ACTA Medical Health Sciences

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Abstract

The use of the anesthetic technique for cesarean section is still debatable because of the side effects caused by anesthesia for mothers and neonates. The succeed to determine anesthetic technique can be seen from the outcome of the final condition of the mother and the neonates. The assessment of the succeed to determine anesthetic technique in neonates has been using the Apgar score by assessing the clinical status of the newborn in the first and fifth minutes. This research is aimed to understand the comparison between Apgar scores in cesarean section using general anesthesia sevoflurane and spinal anesthesia bupivacaine. This research is analytical retrospective with a cross-sectional study approach, using a total sample of 40 patients who performed cesarean section from August to November 2021, the samples were taken by consecutive sampling. The data was taken from the medical records of the Melinda Mother and Child Hospital, Bandung. The results of this research showed that there was no significant difference in the APGAR Score first minute between general anesthesia and spinal anesthesia (p=0,054) in the fifth minute (p=0,708). There was no effect on APGAR scores in the general anesthesia sevoflurane group and spinal anesthesia bupivacaine group, and both anesthetic groups had a good effect on neonates   DOI : 10.35990/amhs.v1n3.p128-136
Bipolar disorder - difficulties in managing emotional ups and down in an entertainer life: a case report Arlisa Wulandari; Meily D Kusuma; Rachmaditya Pancarani
ACTA Medical Health Sciences Vol. 1 No. 3 (2023): ACTA Medical Health Sciences
Publisher : ACTA Medical Health Sciences

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Abstract

Bipolar disorder is a chronic and recurrent disorder, a brain disorder that causes changes in a person’s mood, energy, and ability to function. Patients have alternate increased mood and activities (mania, hypomania, or “ups” period) and declining mood and activities (depressive or “downs” period) in their life. Symptoms of the manic episodes of bipolar disorder include sensitive feelings, lack of rest, and shot up self-esteem, while the depressive episodes bring loss of interest, more or less sleep than usual, anxiety, a feeling of worthlessness, and lack of concentration. Bipolar disorder is a severe mental disorder with a fairly high prevalence of 1%- 2% and is the 5th cause of disability in the world. Many factors have been considered to contribute to this disorder. While there is strong evidence that some genetic and environmental factors are associated with bipolar disorder, only a few can provide sufficient evidence to establish causality. This report discusses the case of a new manic episode of bipolar disorder that occurs in a woman aged 25 years old who works as a public figure, announcer, and entertainer. The patient has been hospitalized several times and received various pharmacotherapy and psychotherapy but still having difficulties in managing the ups and downs of her emotion. A lot of individual factors must be considered in managing patients with bipolar disorder   DOI : 10.35990/amhs.v1n3.p137-143
Description of term pregnant women in labor with COVID-19: a literature review Jeffry Iman Gurnadi; Zulfi Nur Rokhmawansyah; Sri Quintina Indriyana
ACTA Medical Health Sciences Vol. 1 No. 3 (2023): ACTA Medical Health Sciences
Publisher : ACTA Medical Health Sciences

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Abstract

The coronavirus disease 2019 (COVID-19) pandemic has brought a major impact to health systems and societies worldwide. However, knowledge about the effect of COVID-19 infection during pregnancy and the perinatal outcome is still limited and no specific recommendations available yet on the management of this condition. This was a literature review study on the characteristics of pregnant women, types of delivery, and neonatal outcomes associated with COVID-19. The database used as the literature source were PubMed, AJOG, NCBI, RCOG, and Google Scholar and the search was performed on the articles published from July 2021 to August 2021 that meet the inclusion criteria. Eleven articles were included in this study and were extracted and analyzed using statistic summary. The majority of the term pregnant women in labor with COVID-19 were 21-35 years old (86.4%) and 55.5% were multiparous, with the majority of them delivered their baby through caesarean section (74.3%). The perinatal outcomes demonstrated that a small percentage of newborns experienced low birth weight (10.9%) and asphyxia (3.3%). Further studies are needed regarding vertical transmission from women in labor with COVID-19 to their baby.   DOI : 10.35990/amhs.v1n3.p144-149
Description of breast cancer patients at Hasan Sadikin hospital Bandung based on age and stadium Lukmana Lokarjana; Endah Hamidah Abbas; Nurul Aida Fathya; Ajeng Wahyuni Kartika
ACTA Medical Health Sciences Vol. 2 No. 1 (2023): ACTA Medical Health Sciences
Publisher : ACTA Medical Health Sciences

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Abstract

Breast cancer is a disease when normal cells are genetically mutated and become abnormal. Cells can divide and proliferate abnormally and invade breast tissue originating from the ductal epithelium or its lobules. Malignant disease caused by breast cancer is a significant problem faced by women around the world. In 2017, breast cancer experienced by women ranked firstin new cases, namely 252,710 cases. Every increase in age is thought to be one factor influencing breast cancer incidence due to long-term hormonal exposure. The study’s objective was to describe the age and stage levels of the patients with breast cancer at Hasan Sadikin Hospital Bandung, employing descriptive method. The collected data was obtained from the medical records of breast cancer patients recorded between January to December 2018 at the Surgical Oncology Unit of Hasan Sadikin Hospital Bandung. Sampling was carried out using a total sampling technique. The results showed there were 414 patients with breast carcinoma. Breast cancer was primarily found at the age of 36-50 years in 52.7% of cases. The most prevalent stage of breast cancer is stage III B, with 41.1%. Breast cancer incidence increases with age, and the high proportion in stage III is due to the lack of information and awarenessabout early detection and a delay in seeking treatment. In order to reduce the number of breast cancer cases, it is recommended that related regional health installations/facilities provide further education and information regarding the dangers of breast cancer for women.
Strategy for implementation of School child immunization month program In covid-19 pandemic at batujajar health center Sri Quintina Indriyana; Desy Linasari; Enung Masruroh
ACTA Medical Health Sciences Vol. 2 No. 1 (2023): ACTA Medical Health Sciences
Publisher : ACTA Medical Health Sciences

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Abstract

The COVID-19 pandemic has hindered one of the government’s health sector programs, the School Child Immunization Month (BIAS). The complete immunization program must still follow the schedule to protect children from immunization-preventable diseases. This study sought strategies, processes, and obstacles in implementing the BIAS program during the COVID-19 pandemic at Batujajar Health Center from December 2020 to January 2021. The study design was a qualitative method by conducting in-depth interviews. The informants were selected through a purposive sampling technique to obtain the information required for the study. The results showed that immunization was only administered in safe zones, and socialization was distributed from the Community Health Centre to schools by WhatsApp (WA) application. The school used WA to deliver the socialization to parents, then recorded the students to immunize, and chose places fulfilling health protocols. The BIAS process during the COVID-19 pandemic was the selection of place, time, and the number of people involved for BIAS with the health protocol, monitoring by the immunization program coordinator through field officers reporting, and evaluations during monthly workshops. Some problems occurring in the BIAS program were there were external obstacles like school’s difficulty applying health protocols during the administration, and some parents’ resistance to children’s immunization, misinformation that it was a vaccine for COVID-19 or the vaccine was expired, children were sick of afraid of the syringe. Better socialization and coordination on the implementation of this program was needed

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