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All Journal Folia Medica Indonesiana Dental Journal (Majalah Kedokteran Gigi) Indian Journal of Forensic Medicine & Toxicology
Andra Rizqiawan
Faculty Of Dental Medicine, Universitas Airlangga, Surabaya
Dentistry Public Health Other

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Identification of Single Nucleotide Polymorphism on Bone Morphogenetic Protein 2 Gene in Non-Syndromic Cleft Lip/ Palate Patient Mala Kurniati; RM Coen Pramono D; Agung Sosiawan; David Sontani Perdanakusuma; Hari Basuki Notobroto; Andra Rizqiawan
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16954

Abstract

Cleft lip/palate (CL/P) is one of the most common birth defects in humans. Haploinsufficiency in genesBone Morphogenetic Protein (BMP) 2 is thought to play an important role in the incidence of CL/P. Thisstudy aimed to identify changes in the nucleotide (Single Nucleotide Polymorphism/SNP) BMP 2 rs235768A>T gene in CL/P patient in Indonesia. Seventy samples of DNA that were successfully amplified andrestricted consisted of patient and control samples with the three of which were used for sequencing. Basedon the analysis using restriction enzymes and Finch TV and Bioedit software programs, this study identifieda change from nucleotide A to nucleotide T which is a mutation missense (Serine-Arginine/TCA-TCT).Based on the results of the Fisher’s exact test, there was difference in genotype frequency between the CL/Pgroup and the control. Meanwhile, there was no difference in allele frequencies between the two groups. Theallele frequency T has a higher value than the frequency of the allele A.
Considerations in performing odontectomy under general anesthesia: case series Anindita Zahratur Rasyida; Andra Rizqiawan
Dental Journal (Majalah Kedokteran Gigi) Vol. 51 No. 4 (2018): December 2018
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1116.574 KB) | DOI: 10.20473/j.djmkg.v51.i4.p185-188

Abstract

Background: An odontectomy constitutes a common surgical procedure performed by oral and maxillofacial surgeons on a daily basis. The anesthesia procedure required during this form of operation may involve the administering of a general anesthesia which, while a safe procedure when performed by an anesthesiologist, still involves an element of risk and should only be undertaken with appropriate safeguards. Various measures, not only anxiety control-based, are suggested in this article. Purpose: The purpose of this study was to report considerations factors, other than anxiety, as indications in performing odontectomy conducted under a general anesthesia at Universitas Airlangga Hospital, Surabaya, Indonesia. Cases: Four cases of patients who had undergone an odontectomy under a general anesthetic are reported here. Case management: The four cases of management involved odontectomies conducted under a general anesthetic for a variety of reasons with contrasting outcomes. The treatment of the four patients was based on an anatomical approach and previously ineffective pain control due to greater trauma. One of the patients also suffered from schizophrenia that produced comorbidity requiring holistic observation. This individual required intricate surgery whose performance was challenging under a local anesthetic. None of our other patients suffered from serious complications related either to surgery or the administering of a general anesthetic. Conclusion: In conclusion, important factors relating to an odontectomy performed under a general anesthetic on four patients in Universitas Airlangga Hospital, Surabaya included: anxiety, anatomical approach, adequate pain control, comorbidity of systemic medical conditions and the potential need for surgical procedures difficult to perform under a local anesthetic.
Case report: Dentigerous Cyst and Canine Impaction at the Orbital Floor Ferdian rizky Hutomo; Ellen Satya Pratiwi; Viskasari P Kalanjati; Andra Rizqiawan
Folia Medica Indonesiana Vol. 55 No. 3 (2019): September
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (220.256 KB) | DOI: 10.20473/fmi.v55i3.15508

Abstract

Dentigerous cysts are cysts of the epithelial lining of the jaws derived from the dental follicle of unerupted teeth. These cysts are often found during routine radiographic examination along with unerupted teeth. Dentigerous cysts are usually asymptomatic unless the size becomes large, thus causing swelling. This case report describes the management of dentigerous cyst in the upper left canine region with canine impaction to the orbital floor. Dentigerous cyst was treated with cyst enucleation but the impacted canine was not taken because of the magnitude of risk that can occur which was a disruption to the eye muscle. Conclusion. Treatment of dentigerous cysts can be performed by enucleation technique and management related the impacted tooth at the orbital floor needs a further evaluation consideration.
Co-Authors Agung Sosiawan Anindita Zahratur Rasyida David Sontani Perdanakusuma Ellen Satya Pratiwi Ferdian rizky Hutomo Hari Basuki Notobroto Mala Kurniati RM Coen Pramono D Viskasari P. Kalanjati