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All Journal Sumatera Medical Journal
Hanafie, Achsanuddin
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Immunology & microbiology Medicine & Pharmacology

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Equianalgesic Oxycodone, Continuous Intravenous Morphine in Post- Long Bone Surgery Franz Josef Tarigan; Hanafie, Achsanuddin; Arifin, Hasanul; Wijaya, Dadik Wahyu
Sumatera Medical Journal Vol. 2 No. 3 (2019): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v2i3.1240

Abstract

Oxycodone and morphine are powerful analgesic drugs used for post-operative pain management. There is no studies have been conducted to assess the dose equivalency between the two drugs. To get an equianalgesic dose of Oxycodone and Morphine. This study was using a double-blind randomized clinical trials, 48 samples, ages 21-60 years, PS ASA I-II, which will get an elective orthopedic surgery using general anesthesia tech-niques. Oxycodone (group A) : Morphine (group B) (Initial 5mg than continuous 1 mg/hour : initial dose 4mg than continuous 0,5 mg/hour). Average drug dose for group that takes morphine and oxycodone (3.90 ± 0.46 mg : 1.46 ± 0.51 mg). No significant difference between the average dose (p <0.05). Equianalgesic dosein group Oxycodone and Morphine is 1.4 mg: 3.9mg.
Co-Authors Franz Josef Tarigan Hasanul Arifin Wijaya, Dadik Wahyu