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Pengaruh Gel Kulit Nanas Madu Terhadap Penyembuhan Luka Terbakar Derajat Dua Pada Tikus Putih (Rattus Novergicus) Rusmini, Hetti; Djunishap, Asmia; Naufal, Muhammad Nuriy Nuha; Hanif, Muhammad Fikri
Sriwijaya Journal of Medicine Vol. 2 No. 3 (2019): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (876.019 KB)

Abstract

Kulit nanas (Ananas comosus. L) merupakan limbah dari olahan buah nanas yang populer dikonsumsi oleh masyarakat. Kulit nanas mengandung senyawa flavonoid yang mampu mempercepat rposes penyembuhan luka bakar derajat 2. Tujuan dari penelitian ini adalah untuk mengetahui efek penyembuhan luka bakar dari gel kulit nanas pada tikus yang telah diberikan luka bakar derajat 2. Penelitian ini merupakan penelitian eksperimental dengan desain post test only control group. Ekstrak kulit nanas dibuat dengan menggunakan metode ekstraksi maserasi. Metode yang digunakan dalam uji efektifitas penyembuhan luka bakar derajat 2 ini menggunakan tikus putih (Rattus novergicus). Sampel terdiri dari 5 kelompok perlakuan yaitu gel kulit nanas dengan konsentrasi 10%, 20%, dan 30% dan kelompok kontrol bioplacenton disertai kontrol negatif. Analisis data menggunakan One Way ANOVA. Hasil penelitian ini adalah efektivitas gel kulit nanas dengan konsentrasi optimal 20% dengan efek penyembuhan mampu meyamai obat komersil bioplasenton.
JUMLAH LEUKOSIT DAN DERAJAT KLINIS PENDERITA INFEKSI DENGUE DI RSUD DR. H. ABDUL MOELOEK LAMPUNG: Number of Leukosites and Clinical Degree of Dengue Infection Patients at Dr. H. Abdul Moeloek Lampung Hidayat; Rusmini, Hetti; Prasetia , Toni; Setiawan, Henri
JURNAL ILMU DAN TEKNOLOGI KESEHATAN TERPADU Vol. 1 No. 1 (2021): Jurnal Ilmu dan Teknologi Kesehatan Terpadu
Publisher : Poltekes Kemenkes Tanjungpinang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (319.541 KB) | DOI: 10.53579/jitkt.v1i1.10

Abstract

Dengue hemorrhagic fever (DHF) is an infectious disease caused by the dengue virus transmitted by mosquitoes. Hematological abnormalities in the form of a decrease in the number of leukocytes which are influenced by the clinical degree due to stress on the bone marrow can occur in cases of DHF. The decrease or increase in the number of leukocytes was thought to be related to the clinical degree of DHF in previous studies. This study aimed to determine the relationship between the number of leukocytes and the clinical degree in patients with dengue infection. This study used an observational analytic method with a cross-sectional approach. The population consisted of 39 patients with dengue infection. The data on the results of the examination of the number of leukocytes and the clinical degree were obtained from medical record documents. Data analysis was performed using the Spearman correlation test. 39 study subjects suffering from dengue infection consisting of clinical degrees I (30.8%), II (61.5%), and III (7.7%). The leukocyte count was between 4,000-10,000/µL (59%) and the leukocyte count <4,000/µL (41%). The mean number of leukocytes at clinical grade I was 4.183/µL, at clinical grade II was 4.754/µL and clinical-grade III was 6.100/µL. The results of statistical tests with the Spearman correlation test obtained the value of r = -0.121 and the value of p = 0.462 (p> 0.05). There was no significant relationship between the leukocyte count and the clinical degree of dengue infection. Future researchers are expected to increase the number of research samples so that they can get all clinical degrees of DHF.