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Patilaya, Popi
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Agriculture, Biological Sciences & Forestry Health Professions Medicine & Pharmacology

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Aktivitas Antelmintik Ekstrak Air Daun Puguntano Curanga fel-terrae (Lour.) Merr. Patilaya, Popi; Husori, Dadang Irfan
Jurnal Farmasi Indonesia Vol 7, No 4 (2015)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfi.v7i4.195

Abstract

Penelitian ini dilakukan untuk menentukan aktivitas antelmintik ekstrak air daun puguntano (Curanga fel-terrae). Daun puguntano diekstraksi dalam air suling dengan pendidihan selama 10 menit. Cacing Pheretima posthuma dipaparkan ke dalam ekstrak air daun puguntano konsentrasi 10, 20, 30, dan 40 mg/ml selama 5 jam. Larutan albendazol 10 mg/ml dan salin masing-masing digunakan sebagai kontrol positif dan kontrol negatif. Aktivitas antelmintik ditentukan dengan mengamati waktu paralisis dan kematian Pheretima Posthuma. Hasil penelitian menunjukkan bahwa ekstrak air daun puguntano konsentrasi 20 - 40 mg/ml menyebabkan paralisis dan kematian Pheretima Posthuma masing-masing antara 14,27 - 36,82 menit dan 18,69 - 42,47 menit. Penelitian ini menunjukkan bahwa ekstrak air daun puguntano memiliki potensi aktivitas antelmintik.
KARAKTERISTIKEKSTRAK AIR DAUN PUGUNTANO [Curanga fel-terrae (Lour.) Merr.] YANG BERPOTENSI SEBAGAI ANTELMINTIK Patilaya, Popi; Husori, Dadang Irfan
Jurnal Ilmiah Manuntung Vol 1 No 1 (2015): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (70.106 KB) | DOI: 10.51352/jim.v1i1.18

Abstract

OBJECTIVE: This study aimed to determine the characteristics of the water extract of leaves puguntano (Curanga fel-terrae (Lour.) Merr.) Using spectroscopic methods and phytochemical screening.METHODOLOGY: phytochemical screening performed to analyze compounds alkaloids, flavonoids, glycosides, anthraquinone glycosides, saponins, tannins, cyanogenic glycosides, and triterpenoids / steroids. Analyses were performed using FTIR spectrophotometer (Shimadzu) with IR Solution software. The wavelength is set at 4000 – 400 cm-1 with a resolution of 4 cm-1 and 16 scanner.RESULTS: Puguntano leaf water extract contains flavonoids, glycosides, saponins, tannins, steroids, and terpenoids. Infrared spectrum of puguntano leaf aqueous extract showed a O – H fuctional group at 3313.71 cm-1, C – H at 2974.23 and 2881.65 cm-1, C = C at 1689.65 and 1597.06 cm-1, C – O at 1265.30 and 1076.28 cm-1 and group C – H aromatics at 813.96 cm-1 in the fingerprint region
Co-Authors Husori, Dadang Irfan