Dewi Yunia Fitriani
Division Of Occupational Medicine, Faculty Of Medicine, Universitas Indonesia, Indonesia

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Biomonitoring of Acetylcholinesterase (AChE) Inhibitor and the Association with Hypertension among Farmers in Bandung, Indonesia Mulyana Mulyana; Iwan Sugiarta; Lim Jen Fuk; Vani Nur Pratami; Dewi Yunia Fitriani; Nuri Purwito Adi; Dewi Sumaryani Soemarko
The Indonesian Biomedical Journal Vol 12, No 4 (2020)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v12i4.1220

Abstract

BACKGROUND: The use of acetylcholinesterase (AChE) insecticides is still widely used by farmers in flower and agricultural centers. However, biological monitoring of farmers is still very rare in Indonesia. AChE inhibitors are reported to have toxic effects on various organs.METHODS: This study involved 120 subjects in Cihideung, Cikole and Pangalengan areas. All subjects have been interviewed, physically examined and biological sample taken by medical team. Descriptive analysis was performed to assess general conditions of the subjects and AChE erythrocyte activity enzyme at pseudo-baseline and the next 3 months from pseudo-baseline. Statistical analysis have been performed of the pseudo-baseline AChE erythrocyte activity with hypertension and history of exposures.RESULTS: The median value of pseudo-baseline AChE erythrocyte activity was 8.10 (1.3-14.25) U/g hematocrit. In the comparison between pseudo-baseline and 3 month from pseudo-baseline AChE activity, 7 respondents from 19 respondents (36.84%) had lower enzyme activity than 70% and the others subjects have higher activity value. AChE erythrocyte activity is associate with frequency of insecticide exposures. AChE erythrocyte activity (p=0.04; Exp (B)=2.937 CI 95%=1.049-8.224) and age (p=0.025; Exp (B)=3.872 CI 95%=1.180-12.703) are independent risk factors for hypertension in farmworker.CONCLUSION: AChE erythrocyte activity associated with frequency of insecticide exposures and hypertension among farmworkers.KEYWORDS: AChE erythrocyte activity, frequency of insecticide expsoures, hypertension
Parkinson’s in Farmers, Could it be Caused by the Paraquat Herbicide Exposure? Arriz Akbar Sukadi; Dewi Yunia Fitriani; Levina Chandra Khoe
The Indonesian Journal of Community and Occupational Medicine Vol. 2 No. 1 (2022): ijcom
Publisher : ILUNI MKK FKUI and PRODI MKK FKUI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53773/ijcom.v2i1.44.58-65

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Many studies have been carried out to assess the safety of the widespread use of pesticides in agriculture with diseases in farmers. A 52-year-old female farmer suffered Parkinson’s after working 27 years using paraquat herbicide. This study was conducted to obtain answers about the impact of paraquat exposure on the incidence of Parkinson’s in farmers through evidence-based case reports (EBCR) derived from a literature review.The review was conducted through the search and selection method of articles in PubMed, ProQuest, and Cochrane Library to answer research questions. The article search process used the keywords “paraquat AND Parkinson AND farmer”. Article selection was carried out using predetermined inclusion and exclusion criteria. In the initial search, 35 articles were retrieved and through the selection process three articles of the meta-analysis systematic review were selected.Selected articles from Tangamornsuksan and Vaccari show a statistically significant association between paraquat exposure and the incidence of Parkinson’s disease (PD) in workers, with a pooled OR of 1.70 and 1.24. Meanwhile, Yan’s study shows that duration of exposure to pesticides increases the risk of PD. The result showed a 5 and 10 years of duration exposure to pesticide were associated with a 5% and 11% augment in the risk of PD. All studies applied validation to reduce bias and heterogeneity effects or inadequate statistical methods.Based on the results of this evidence-based case report, it shows that the epidemiological studies taken can prove the possibility that Parkinson’s disease in this farmer is caused by exposure to paraquat.
Konflik Pekerjaan-Keluarga dan Gangguan Mental Emosional pada Perawat Perempuan di Rumah Sakit Rujukan Nasional di Jakarta Dewi Yunia Fitriani; Dewi Sumaryani Soemarko; Indra Hardjono; Astrid Sulistomo; Aria Kekalih
Majalah Kedokteran Indonesia Vol 70 No 10 (2020): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, V
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.70.10-2020-268

Abstract

Introduction: Emotional mental disorder (EMD) is a state of psychological distress that, if not handled properly, can lead to severe mental disorders. One potential psychosocial hazard that is thought to be related to mental health disorders is work-family conflict (WFC). The issue of family-work balance has become an important issue among Indonesian female workers, especially with the rapidly growing female worker society and the strong family culture. This study aimed to identify the association between work-family conflict and emotional mental disorder in female nurses. Methods: This cross-sectional study included 264 female nurses who work at national referral general hospital in Jakarta. Their emotional mental disorder was measured using Self-Reported Questionnaire 20 (SRQ-20) and the work-family conflict was measured using the Work-Family Conflict Scale (WCFS). Results: The prevalence of emotional mental disorder in female nurses was 23.5%. The most dominant factor associated with emotional mental disorder is work-family conflict (OR 2,40, CI 95% 1,32-4,35, p=0,004). Conclusion: There is a significant association between work-family conflicts and emotional mental disorders in female nurses in Indonesia. Nurses with work-family conflicts are more likely to have emotional mental disorders. Regular mental health checks and counseling should be performed along with periodic health checks.
Laporan Kasus: Katarak Akibat Kerja pada Buruh Perkebunan Kelapa Sawit Sugiharto Sugiharto; Dewi Yunia Fitriani
Majalah Kedokteran Indonesia Vol 72 No 4 (2022): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.72.4-2022-713

Abstract

Introduction: Cataract in workers need to be distinguished whether it is an occupational disease or not. Palm oil plantation workers are one of the high-risk jobs for potential hazards in the workplace that have an impact on health, one of which is cataract. Case report: A 38-year-old male oil palm plantation worker with complaints of blurred eyes since 1.5 years ago, sensitivity with lights and glare, and clouded. He was exposed ultraviolet (UV) rays 5 hours every day for 18 years without UV protective eyewear. To on examination revealed visual acuity in the right eye was 6/60 and the left eye was 6/9, both posterior subcapsular lenses opacities, vitreous papillae on the right were blurred.Discussion: Occupational cataract in oil palm plantation workers can be caused by prolonged exposure of UV rays, without wearing UV protective eyewear. The examination revealed decreased vision, posterior subcapsular lens opacities and blurred papillae. Determination of occupational cataract refers to the Seven Steps Occupational Diagnosis method issued by PERDOKI (Indonesian Association of Occupational Medicine Specialists).Conclusion: Occupational cataract can be diagnosed by the Seven Steps Occupational Diagnosis method and prevented by administrative controls and the use of UV protective eyewear.
Correlation of Plasma Melatonin Concentration and Alertness Level Among Female Nurses in Jakarta Indonesia Kresna, Andreas; Fuk, Liem Jen; Widyahening, Indah Suci; Soemarko, Dewi Sumaryani; Fitriani, Dewi Yunia
Occupational and Environmental Medicine Journal of Indonesia Vol. 1, No. 2
Publisher : UI Scholars Hub

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Abstract

Background Working in shift especially night shift could alter alertness level, increase fatigue, and working accident. One of the factors that affect the circadian rhythm were melatonin. Melatonin was a hormone that regulate the wake and sleep cycle that have an impact on alertness levels. This study was aimed to find correlation between plasma melatonin and alertness level. Methods A cross-sectional study was conducted on 40 female night shift nurses. Individual characteristics were obtained by self-administered questionnaire. Plasma melatonin concentrations and alertness level was collected twice at night time (11 pm – 00 am) and at morning (7 am − 8 am). Spearman or Pearson test was used to find correlation between melatonin concentrations and Psychomotor Vigilance Test (PVT). Results Mean age was 28.4 (±4.9) years with working experience varied from 1-16 years. Plasma melatonin concentrations among female night shift nurses were higher before working hours than after duty. Range of plasma melatonin value was 10-240 pg/ml and Alertness was in the same manner with average alertness level at night was 301.2 ± 51.6 ms and 293.2± 49.7 ms at morning. There was a weak correlation between plasma melatonin concentration and alertness level difference before and after duty (r = 0.37; p = 0.016). Conclusion There was weak correlation between plasma melatonin and alertness level in night shift workers before and after duty. To Maintain alertness level reduction and melatonin secretion, night shift workers should rest at least 30 minutes during their working hours, always keep the lights on while on duty and should not work more than one shift on the same day, and providing healthy foods.
The Vigilance Screening Tool in The Workplace: Scoping Review Sugiarta, Iwan; Fitriani, Dewi Yunia; Mansyur, Muchtaruddin
Occupational and Environmental Medicine Journal of Indonesia Vol. 1, No. 2
Publisher : UI Scholars Hub

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VIGILANCE SCREENING TOOLS IN THE WORKPLACE: SCOPING REVIEW ABSTRACT Background: Vigilance performance examination is currently used widely in many disciplines, neurophysiology, sleep medicine, psychology to its application to workers whose daily activities require prime vigilance. A more objective inspection of vigilance has not yet become a routine screening examination for workers to detect decreased vigilance as part of a fit-to-work assessment, but only in the form of research / study using a partial sampling technique. The aim is to provide an overview of vigilance screening tools in the workplace, its terminologies and how the process of maintaining quality such as calibration and validation. Methods: A literature search was independently conducted from the Pubmed database. We are looking for only articles that meet the following criteria: discussions on the terminology of vigilance, or research on workers that use vigilance examination tools, or research that develops its examination tools. Results: Three articles were found that specifically discussed the term vigilance, 30 studies on workers that used vigilance performance examination tools, and 15 studies discussing the development of these tools. The definition of vigilance is still not firmly established and has been used interchangeably and leading to confusion. Workplace research has used product-based smart devices rather than dedicated hardware, as well as a number of studies that have focused on tools development. Conclusion: Vigilance is the capability to be aware of potentially relevant or capability to be sensitive to unpredictable changes in one's environment including a quantitative and a temporal dimension. Although vigilance testing may not pinpoint the exact cause of vigilance decrement, using it as a screening tool in workplace holds great potential. Smart-device-based tools are relatively easy to obtain and inexpensive, but face enormous challenges related to calibration issues, validation issues, manufacturer's service of life, and firmware updates. It's important to consider vigilance screening tools with low-cost, portable, robust, future-proof, and easily validated with clear calibration or validation methods. Keywords: alertness, neuropsychological tests, psychomotor performance, reaction time, vigilance
The Effectiveness of Education through Web-Based Seminar in Increasing Knowledge about the Early Detection and Reporting of Occupational Diseases Monintja, Keyne Christa; Soemarko, Dewi Sumaryani; Fitriani, Dewi Yunia; Herqutanto, Herqutanto; Wibowo, Suryo
Occupational and Environmental Medicine Journal of Indonesia Vol. 2, No. 1
Publisher : UI Scholars Hub

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Background: In 2022, the Indonesian Occupational Medicine Association (IOMA) collaborated with oil and gas companies and conducted a web-based seminar (webinar) to enable participants to recognize occupational disease earlier and enhance reporting in companies. We aimed to investigate the effectiveness of the webinar in increasing the intended knowledge. Method: The webinar was separated into three batches, with different participants per batch. Using a one-group pretest-posttest design, we utilized secondary data from IOMA. The effectiveness of the webinar was determined by participants' satisfaction and knowledge as measured by pre-test and post-test. After performing item analysis, we removed poor discriminating items in pre-test and post-test ( Results: Data was gathered from 147 subjects (23.8%, 34%, and 42.2% of the three batches, respectively). Except for company status in the second batch (P = 0.045), there was no significant difference in initial knowledge based on the individual factors studied. Significant knowledge improvement was observed post-webinar in each batch compared to the initial. (P < 0.05). The correlation between satisfaction and post-test scores was negligible (r < 0.3; P > 0.05). Conclusion: The initial knowledge of oil and gas company workers in early detection and reporting of OD was low (
Prognosis of COVID-19 on Workers with History of Asthma: An Evidence-Based Case Report Parmitasari, Parmitasari; Fitriani, Dewi Yunia; Widyahening, Indah S
Occupational and Environmental Medicine Journal of Indonesia Vol. 2, No. 1
Publisher : UI Scholars Hub

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Background. As the COVID-19 pandemic occurs, those with asthma were thought to have an increased risk of infection. Question arisen whether special preparation for severe clinical outcomes might be needed for remote site workers. Method. A literature search was conducted through PubMed, Scopus and ProQuest databases, as well as hand searched. The inclusion criteria were systematic review, cohort study, retrospective study, cross sectional study, COVID-19, asthma, and ICU. Then, they were critically appraised based on Center of Evidence-Based Medicine, Oxford University, Critical Appraisal for Prognostic Studies and Systematic Reviews. Result. Three systematic review studies and three retrospective cohort studies were found. Systematic reviews by Sunjaya, et al. (2021) and Hussein, et al. (2021), also retrospective cohort study by Calmes, MD, et al. (2021) showed no significant difference in risk requiring admission to ICU for asthmatic compared to non-asthmatic (RR 1.19; CI 95%: 0.93 – 1.53; p= 0.16), (RR= 1.64, 95%CI = 0.67-3.97; p=0.27), and (OR = 1.4 (95% CI = 0.64-3.2); p =0.39), respectively. Systematic review by Liu (2021), showed no significant difference in asthma prevalence between ICU and non-ICU patients (RR, 1.19; 95% CI, 0.92-1.54; P =0 .17; I2 = 48.6%;). Cohort study by Choi, et al (2020) showed asthma was not a predictive factor for ICU admission in COVID-19 patients (OR 0.656 (95%CI= 0.295 – 1.440); p value =0.302). Contrary, cohort study by Jin, MMed, et.al (2020) showed that COVID-19 patients with asthma had a higher proportion of ICU admission than those who do not have. Conclusion COVID-19 workers with asthma does not have a higher risk of ICU admission.