Dewi Yunia Fitriani
Division Of Occupational Medicine, Faculty Of Medicine, Universitas Indonesia, Indonesia

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Biomonitoring of Acetylcholinesterase (AChE) Inhibitor and the Association with Hypertension among Farmers in Bandung, Indonesia Mulyana Mulyana; Iwan Sugiarta; Lim Jen Fuk; Vani Nur Pratami; Dewi Yunia Fitriani; Nuri Purwito Adi; Dewi Sumaryani Soemarko
The Indonesian Biomedical Journal Vol 12, No 4 (2020)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v12i4.1220


BACKGROUND: The use of acetylcholinesterase (AChE) insecticides is still widely used by farmers in flower and agricultural centers. However, biological monitoring of farmers is still very rare in Indonesia. AChE inhibitors are reported to have toxic effects on various organs.METHODS: This study involved 120 subjects in Cihideung, Cikole and Pangalengan areas. All subjects have been interviewed, physically examined and biological sample taken by medical team. Descriptive analysis was performed to assess general conditions of the subjects and AChE erythrocyte activity enzyme at pseudo-baseline and the next 3 months from pseudo-baseline. Statistical analysis have been performed of the pseudo-baseline AChE erythrocyte activity with hypertension and history of exposures.RESULTS: The median value of pseudo-baseline AChE erythrocyte activity was 8.10 (1.3-14.25) U/g hematocrit. In the comparison between pseudo-baseline and 3 month from pseudo-baseline AChE activity, 7 respondents from 19 respondents (36.84%) had lower enzyme activity than 70% and the others subjects have higher activity value. AChE erythrocyte activity is associate with frequency of insecticide exposures. AChE erythrocyte activity (p=0.04; Exp (B)=2.937 CI 95%=1.049-8.224) and age (p=0.025; Exp (B)=3.872 CI 95%=1.180-12.703) are independent risk factors for hypertension in farmworker.CONCLUSION: AChE erythrocyte activity associated with frequency of insecticide exposures and hypertension among farmworkers.KEYWORDS: AChE erythrocyte activity, frequency of insecticide expsoures, hypertension
Parkinson’s in Farmers, Could it be Caused by the Paraquat Herbicide Exposure? Arriz Akbar Sukadi; Dewi Yunia Fitriani; Levina Chandra Khoe
The Indonesian Journal of Community and Occupational Medicine Vol. 2 No. 1 (2022): ijcom

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53773/ijcom.v2i1.44.58-65


Many studies have been carried out to assess the safety of the widespread use of pesticides in agriculture with diseases in farmers. A 52-year-old female farmer suffered Parkinson’s after working 27 years using paraquat herbicide. This study was conducted to obtain answers about the impact of paraquat exposure on the incidence of Parkinson’s in farmers through evidence-based case reports (EBCR) derived from a literature review.The review was conducted through the search and selection method of articles in PubMed, ProQuest, and Cochrane Library to answer research questions. The article search process used the keywords “paraquat AND Parkinson AND farmer”. Article selection was carried out using predetermined inclusion and exclusion criteria. In the initial search, 35 articles were retrieved and through the selection process three articles of the meta-analysis systematic review were selected.Selected articles from Tangamornsuksan and Vaccari show a statistically significant association between paraquat exposure and the incidence of Parkinson’s disease (PD) in workers, with a pooled OR of 1.70 and 1.24. Meanwhile, Yan’s study shows that duration of exposure to pesticides increases the risk of PD. The result showed a 5 and 10 years of duration exposure to pesticide were associated with a 5% and 11% augment in the risk of PD. All studies applied validation to reduce bias and heterogeneity effects or inadequate statistical methods.Based on the results of this evidence-based case report, it shows that the epidemiological studies taken can prove the possibility that Parkinson’s disease in this farmer is caused by exposure to paraquat.
Konflik Pekerjaan-Keluarga dan Gangguan Mental Emosional pada Perawat Perempuan di Rumah Sakit Rujukan Nasional di Jakarta Dewi Yunia Fitriani; Dewi Sumaryani Soemarko; Indra Hardjono; Astrid Sulistomo; Aria Kekalih
Majalah Kedokteran Indonesia Vol 70 No 10 (2020): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, V

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.70.10-2020-268


Introduction: Emotional mental disorder (EMD) is a state of psychological distress that, if not handled properly, can lead to severe mental disorders. One potential psychosocial hazard that is thought to be related to mental health disorders is work-family conflict (WFC). The issue of family-work balance has become an important issue among Indonesian female workers, especially with the rapidly growing female worker society and the strong family culture. This study aimed to identify the association between work-family conflict and emotional mental disorder in female nurses. Methods: This cross-sectional study included 264 female nurses who work at national referral general hospital in Jakarta. Their emotional mental disorder was measured using Self-Reported Questionnaire 20 (SRQ-20) and the work-family conflict was measured using the Work-Family Conflict Scale (WCFS). Results: The prevalence of emotional mental disorder in female nurses was 23.5%. The most dominant factor associated with emotional mental disorder is work-family conflict (OR 2,40, CI 95% 1,32-4,35, p=0,004). Conclusion: There is a significant association between work-family conflicts and emotional mental disorders in female nurses in Indonesia. Nurses with work-family conflicts are more likely to have emotional mental disorders. Regular mental health checks and counseling should be performed along with periodic health checks.
Laporan Kasus: Katarak Akibat Kerja pada Buruh Perkebunan Kelapa Sawit Sugiharto Sugiharto; Dewi Yunia Fitriani
Majalah Kedokteran Indonesia Vol 72 No 4 (2022): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.72.4-2022-713


Introduction: Cataract in workers need to be distinguished whether it is an occupational disease or not. Palm oil plantation workers are one of the high-risk jobs for potential hazards in the workplace that have an impact on health, one of which is cataract. Case report: A 38-year-old male oil palm plantation worker with complaints of blurred eyes since 1.5 years ago, sensitivity with lights and glare, and clouded. He was exposed ultraviolet (UV) rays 5 hours every day for 18 years without UV protective eyewear. To on examination revealed visual acuity in the right eye was 6/60 and the left eye was 6/9, both posterior subcapsular lenses opacities, vitreous papillae on the right were blurred.Discussion: Occupational cataract in oil palm plantation workers can be caused by prolonged exposure of UV rays, without wearing UV protective eyewear. The examination revealed decreased vision, posterior subcapsular lens opacities and blurred papillae. Determination of occupational cataract refers to the Seven Steps Occupational Diagnosis method issued by PERDOKI (Indonesian Association of Occupational Medicine Specialists).Conclusion: Occupational cataract can be diagnosed by the Seven Steps Occupational Diagnosis method and prevented by administrative controls and the use of UV protective eyewear.