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IDENTIFICATION OF CANDIDA SPECIES ON THE SKIN OF DIABETES MELLITUS PATIENTS Al Hafiz, OK Muhammad; Amelia, Rina; Jusuf, Nelva Karmila
Sumatera Medical Journal Vol. 1 No. 01 (2017): The Sumatera Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v1i01.76

Abstract

Background: Intertriginous candidiasis is a type of candidiasis which the lesion lies in the folds of the armpit, groin, intergluteal, folding of the breast, between the fingers or the toes, glans penis, and the umbilicus. One of the risk factors for intertriginous candidiasis is diabetes mellitus (DM). DM is a typical clinical syndrome characterized by the presence of hyperglycemia which is caused by deficiency or the decrease of insulin effectivity. Fungal infection of the skin with Candida species becomes easier in patients with immunocompromised conditions such as DM patients.Objective: To identify the Candida species in DM patient's skin.Method: This research is an observational descriptive study with cross sectional design. This research identifies Candida species from 30 DM patients at The Public Health Center Sentosa BaruMedan who met the inclusion and exclusion criteria by skin scraping with KOH 10% and slide culture.RESULTS: The location of the rash was found in the crotch folds 63.3% and in the intergluteal 36.7%. All samples (100%) showed positive fungus structure with KOH 10% examination. On theexamination of slide culture with Saboraoud Dextrose Agar media and identification of slide colony with Corn Meal Agar medium as many as 60% Candida spesies was found with overallspecies are Candida albicans.Conclusions: The identification of Candida Species on the skin of DM patients showed as many as 60% Candida albicans was found
QUALITY OF LIFE IN VITILIGO PATIENTS AT H. ADAM MALIK GENERAL HOSPITAL MEDAN, INDONESIA Jusuf, Nelva Karmila; putra, imam budi; utami, dina rizki
Sumatera Medical Journal Vol. 1 No. 01 (2017): The Sumatera Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v1i01.79

Abstract

Background: Vitiligo is an acquired depigmenting skin disorder that can affect the patients’ quality of life (QOL).Objectives: The aim of this study was to evaluate the QOL in patients with vitiligo.Patients and Methods: This study included 30 patients with vitiligo. All the patients filled out questionnaires Skindex- 29. Data were compiled and analyzed statistically.Results: Among the 30 vitiligo patients, 73,3 % were women and 26,7 % were men. Mean age of patients were 40.53 ± 12. 91 years old. The mean duration of vitiligo was 9.07 ± 7.643 years. Themean total Skindex-29 score of the subjects was 24.68 ± 7,72. There was significant difference according to age’s group (p =0,035) and sex ( p = 0,01) but there is no significant difference according to duration of disease’s group ( p = 0,582 ).Conclusions: The study findings showed that vitiligo has a significant effect on the patients’ QOL. It seems counselling is needed as part of treatment in vitiligo patients.
QUALITY OF LIFE ASSESSMENT IN SKIN TAG PATIENTS putra, imam budi; Jusuf, Nelva Karmila; Kartayana, Johan
Sumatera Medical Journal Vol. 1 No. 01 (2017): The Sumatera Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v1i01.80

Abstract

Background: Patients with skin disease may experience clinical symptoms, such as itching, pain, and discomfort, that can have a negative impact on quality of life (QOL).Skin tag is a common benign tumor of the skin with small, soft pedunculated protrusion, it commonly occur in axilla, neck and major flexura area, despitethe lesion usually asimptomatic, sometimes patients complainabout cosmetics appereance, itching or discomfort experienced.Objective : The aim of our study was to assess the impact of skin tag lesion on quality of life of patients.Material and Method: This is a descriptive study with a cross sectional design, involving 50 patients with skin tag lesion who visited the Dermatology outpatient clinic Adam Malik GeneralHospital, Medan from September 2016 to October 2016. Thepatients were filled Indonesian version of skindex-29 questionnaire to measures the effects of skin disorders on their QOL.Results: In this study QOL in skin tag patient was fairly good, 38(76%) subjects had a skindex-29 category score<5, and 12(24%) subjects had a skindex-29 score 6-17. We didn’t findimpaired QOL in all skin tag patients.Conclusion : In this study we concludedskin tag does not affect the quality of life of the patients.
The Association Between Skin Types and Acne Vulgaris Tamba, Asnita Bella Putri; Jusuf, Nelva Karmila
Sumatera Medical Journal Vol. 3 No. 1 (2020): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v3i1.3279

Abstract

The skin problem often found on adolescents is acne vulgaris. The pathogenesis of acne vulgaris is multifactorial, from increased production of sebum, hyperproliferation of pilosebaceous follicles, colonization of Cutibacterium acnes, to inflammation process. The elevated sebum production which is often linked to oily skin type could result in acne vulgaris in adolescents. According to Baumann Skin Type, one of the parameters in categorizing skin type is having either oily or dry skin. Acne vulgaris is also found on dry skin. This research aims to find the association between skin types and acne vulgaris. It is an analitic research with cross-sectional method. The data were acquired from 93 students of SMA Santo Thomas 1 Medan who fulfilled the inclusion criteria with stratified random sampling method. The collection of data were primarily carried out with dermatology examination and Baumann Skin Type questionnaire to determine the skin types. Then, they were analyzed with Chi-square test to see the relationship between skin types and acne vulgaris. The obtained results show that 73 (78,5%) out of 93 students suffered from acne vulgaris with predominance being female (39,8%) than male (38,7%), and those in 15-year age group (38,7%). The most commonly observed skin type on samples is oily skin (79,6%). The bivariate analysis with acquired p-value of 0,002 (p<0,05) led to a conclusion that there is a significant association between skin types and acne vulgaris.
Risk Factors Analysis of Premature Canities in Medical Students of Universitas Sumatera Utara Class 2016-2018 Eka Zhaki Safira Lubis; Jusuf, Nelva Karmila
Sumatera Medical Journal Vol. 3 No. 1 (2020): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v3i1.3543

Abstract

Abstract. Background. Premature canities is a terminology to describe a premature graying of hair before the age of 25 in Asians.The ethiopathogenesis of premature canities is still not fully understood, but there are risk factors associated to premature canities such as gender, family history, obesity, smoking, alcohol consumption, other disease, micronutrients deficiencies. Aims: to evaluate risk factors that influence the incidence of premature canities in medical students of University of Sumatera Utara class 2016-2018. Methods: This research is an analytic research with the number of subjects are 80 respondents using bivariate and multivariate analysis using logistic regression test. Results: of the 80 respondents, 57 respondents (71,2%) had premature canities. Based on bivariate analysis, it was obtained p value ≤ 0,05 for family history and stress, Based on multiavariate analysis, it was obtained p value ≤ 0,05 for family history (p value = 0,000), which means family history is the most dominants factors for premature canities. Conclusion: there is a correlation between premature canities and family history and stress and Family history is the most dominant risk factors that associated to premature canities in medical students of University of Sumatera Utara class 2016-2018.
Analysis of Risk Factors for Infant Diaper Dermatitis Khairina, Fadilah Oliv; Jusuf, Nelva Karmila
Sumatera Medical Journal Vol. 3 No. 2 (2020): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v3i2.3678

Abstract

Infants have skin that is easy to get irritated and infected by microorganisms. The use of diapers in infants often causes diaper dermatitis and disturbs the comfort. The diaper dermatitis incidence is quite high in infants aged 0-24 months. This study purposes to determine the factors that influence the infant diaper dermatitis and assess the relationship between these factors and the diaper dermatitis. The study design is an analytical observational with a cross sectional study design. Data retrieval using interview method on respondents use a structured questionnaire to obtain risk factors which are associated with the diaper dermatitis incidence. Bivariate analysis was used to examine the relationship between the diaper dermatitis incidence and contributing factors. The study result is 27 infants (36%) of 75 infants had diaper dermatitis. It was obtained p value ≤ 0.05 for solid food (fishes, p = 0,018) and diarrhea (p = 0,021). The value of p > 0.05 for the variables of age, sex, maternal education level, neighborhood, solid foods (cereals, eggs and fruits), frequency of diaper changes, frequency of bathing, and the use of protective skin cream. The conclusion is there is a correlation between diaper dermatitis and the solid food (fishes) and diarrhea.
Hubungan Indeks Massa Tubuh dengan Akne Vulgaris pada Siswa-Siswi SMA Negeri 7 Medan Deliana, Rizka; Amalia, Rina; Jusuf, Nelva Karmila
Cermin Dunia Kedokteran Vol 46, No 4 (2019): Dermatologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (496.819 KB) | DOI: 10.55175/cdk.v46i4.489

Abstract

Pendahuluan : Akne vulgaris adalah penyakit inflamasi kronis folikel pilosebasus umumnya terjadi pada masa remaja dan dapat sembuh sendiri. Obesitas diduga salah satu faktor yang dapat mempengaruhi terjadinya akne vulgaris. Tujuan : mengetahui hubungan antara IMT dengan akne vulgaris pada siswa-siswi SMA Negeri 7 Medan. Metode : Penelitian observasional analitik desain studi cross sectional dengan metode stratified random sampling pada sampel 90 orang. Data dianalisis menggunakan uji chi-square dilanjutkan dengan menghitung nilai Prevalence Ratio (PR). Hasil : Siswa-siswi SMA Negeri 7 Medan dengan IMT kategori obesitas berisiko akne vulgaris 1,438 kali lebih besar daripada siswa dengan IMT kategori tidak obesitas (p = 0,044).. Simpulan: IMT berhubungan signifikan dengan akne vulgaris pada siswa-siswi SMA Negeri 7 Medan.Introduction : Acne vulgaris is a chronic inflammatory disease of the pilosebasus follicle generally occurs in adolescence.Obesity is thought to be one of the influencing factor. Aim: To examine the relationship between BMI and the incidence of acne vulgaris among SMA Negeri 7 Medan students. Methods: An analytic observational cross sectional study on 90 students collected using stratified random sampling method. The data were analyzed with chi-square, Prevalence Ratio (PR) was calculated. Results: Obese students have 1,438 higher risk to have acne vulgaris than non obese students (p=0,044). Conclusion: There is a significant relationship between BMI with the incidence of acne vulgaris among SMA Negeri 7 Medan students
Pattern of pigmentation disorder in Cosmetic Dermatology Clinic H. Adam Malik General Hospital, Medan, 2012 - 2015 Jusuf, Nelva Karmila
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 2, No. 1
Publisher : UI Scholars Hub

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Abstract

Background: Abnormalities of pigmentation is a cosmetic problem which affects the overall appearance of an individual. Pigmentation disorder are caused by the increase (hypermelanosis) or the decrease (hypomelanosis) amount of melanin. Objective: To determine the pattern of pigmentation disorder in Cosmetic Dermatology Clinic H. Adam Malik General Hospital Medan in 2012-2015. Methods: A retrospective study using subject's medical records from the Cosmetic Dermatology Clinic H. Adam Malik General Hospital Medan in 2012 - 2015, presented descriptively. Results: In 2012 - 2015 the number of patients who visited the Cosmetic Dermatology Clinic were respectively 210, 228, 211, 142. Hypermelanosis were found respectively in 24.76%, 16.20%, 12.79%, 5.63%. Whereas hypomelanosis were found 18.10%, 9.21%, 8.53%, 8.45%. During 2012 - 2015 melasma was the most common disorder found among hypermelanosis group, followed by post inflammatory hyperpigmentation. Meanwhile vitiligo was the only diagnosis in hypomelanosis group. Each year most of the pigmentation disorder patients came from the age group 38-48 years old except in 2015. Women were more affected than men. Conclusion: In 2012-2014, the largest proportion of pigmentation disorder were hypermelanosis, mostly melasma. In 2015, it was hypomelanosis with vitiligo as the diagnosis.
Intense pulsed light (IPL) as adjuvant therapy for acne vulgaris: A case series Oentari, Widyaningsih; Sutrisno, Angie Regina; Jusuf, Nelva Karmila; Nasution, Khairina
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 5, No. 3
Publisher : UI Scholars Hub

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Abstract

Background: Acne vulgaris is a chronic inflammatory disease of the pilosebaceous follicle with polymorphic clinical manifestation typically found on facial, neck and/or back area. The pathogenesis is complex and multifactorial. Management of acne vulgaris is determined based on its severity. Adjuvant therapies, such as intense pulsed light (IPL), have been described in accelerating the healing process during treatment. Case Illustration: We report two cases regarding the usage of IPL as adjuvant therapy in acne vulgaris. Both patients were diagnosed with moderate acne vulgaris. The first patient was given topical adapalene 0.1% gel every night and sunscreen in the morning, and the other patient was given clindamycin gel applied twice a day, benzoyl peroxide 2.5% cream applied once a day at night, and sunscreen in the morning. Both patients were treated using IPL as their adjuvant therapy every three weeks, with a total of 2 IPL sessions in 2 months. Evaluation using clinical and ultraviolet-induced red fluorescence (UVRF) examination showed gradual improvement. Discussion: IPL as an adjuvant therapy of acne vulgaris has been thought to interfere with the function of the sebaceous glands by its direct phototoxic effects and thermal damage. It also has bactericidal effects on C. acnes through the formation of free radicals. The combination of topical treatment and IPL yielded clinical improvements in both patients.Conclusion: IPL may be beneficial as adjuvant therapy in acne vulgaris in this case series.
Plasma malondialdehyde levels related to acne vulgaris severity Puspita, Fitri; Jusuf, Nelva Karmila; Yosi, Ariyati
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 5, No. 3
Publisher : UI Scholars Hub

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Abstract

Background: Acne vulgaris (AV) is a multifactorial disorder characterized by the formation of open and closed comedones, papules, pustules, nodules, and cysts. Oxidative stress plays a role in the pathogenesis of AV. Reactive Oxygen Species (ROS), especially lipid peroxides (LPO), plays a role in mediating acne inflammation. Malondialdehyde (MDA) is one of the byproducts of LPO commonly used as a biomarker of cell damage.Methods: This cross-sectional analytic study consisted of sixty patients with AV. The samples were taken from the blood plasma of AV subjects. An enzyme-linked immunosorbent assay (ELISA) examination was performed. The normality of data distribution was determined using the Kolmogorov-Smirnov test and the differences of plasma MDA levels based on the severity of AV were determined using the Kruskal-Wallis test. P valueResults: Acne vulgaris was predominantly found in women (70%), age group of 18 – 25 years old (73,33%), and patients with family history of AV (61,67%). Higher plasma MDA levels were found in women [5,5 (2,53 – 77,6) nmol/mL], age group of 26 – 35 years [5,66 (2,73 – 25) nmol/mL], and subjects with family history of AV [5,49 (2,53 – 77,6) nmol/mL]. Based on the severity of AV, the severe AV group had highest plasma MDA [13,85 (2,69 – 77,6) nmol/mL], followed by moderate AV group [4,46 (2,53-14,3) nmol/mL] and mild AV [3,78 (2,47-6,88) nmol/mL]. There were differences in plasma MDA level based on the severity of AV (p<0,001).Conclusion: There were differences in plasma MDA levels based on the severity of AV.