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Epidemiology of Escherichia coli as a Critical Pathogen of Bloodstream Infection Patients in Tertiary Referral Hospital Pepy Endraswari; Ni Made Mertaniasih; Firman Setiawan; Ayu Lidya Paramita
Indonesian Journal of Tropical and Infectious Disease Vol. 10 No. 3 (2022)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v10i3.39494

Abstract

Bloodstream infections (BSI), caused primarily by multidrug-resistant Escherichia coli, are a significant cause of morbidity and mortality worldwide. This study aims to evaluate the epidemiology of E. coli as a critical pathogen in patients with bloodstream infections in a tertiary referral hospital. This is a retrospective study using a  descriptive observational research design. This study used a medical record instrument for bloodstream patients in Dr. Soetomo Hospital's inpatient ward with Gram-negative bacteria results of blood cultures in the Clinical Microbiology Laboratory from April 2021 to September 2021. The observed variables include; antimicrobial sensitivity, patient clinical characteristics, demographic data, clinical diagnosis, and clinical outcome. In 6 months, 276 Gram-negative bloodstream infection patients were treated at Dr. Soetomo Hospital. The proportion of E. coli was 17 %.  The main characteristics of patients were over 60 years old (28%), and 54% were female. 63% of E. coli were ESBL, and 9% were carbapenem-resistant microorganisms. High antimicrobial resistance was found in quinolones (100%), ampicillin (93%), piperacillin (74%), tetracycline (72%), ceftriaxone (66%), cefotaxime (65%), ceftazidime (60%), cefazolin (65%), and trimethoprim-sulfamethoxazole (65%). The most common potential determinant profile discovered was linked to immunocompromised status due to malignancy.  The high number of antimicrobial-resistant bacteria showed the importance of strict infection control and updated epidemiology data as a guide for empirical antimicrobial therapy.
Analisis Determinan pada Faktor yang Mempengaruhi Minat Nasabah dalam Menggadaikan Emas di Pegadaian UPS Pasar Anom Anisatul Khair; Firman Setiawan
Al-Kharaj : Jurnal Ekonomi, Keuangan & Bisnis Syariah Vol 6 No 2 (2024): Al-Kharaj: Jurnal Ekonomi, Keuangan & Bisnis Syariah
Publisher : Research and Strategic Studies Center (Pusat Riset dan Kajian Strategis) Fakultas Syariah IAI Nasional Laa Roiba

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47467/alkharaj.v6i2.5420

Abstract

Sharia pawnshops are the best solution in meeting human needs which are increasingly consumerist amidst the development of the digital world which provides easy access for humans to fulfill their lives. Even though banks also issue pawn products, pawnshops still exist with their pawn products because the process is fast, easy and safe without having to queue longer. So here the researchers are interested in examining what factors influence customers' interest in pawning their gold at Pegadaian UPS Pasar Anom. This research uses quantitative methods with primary data obtained directly through distributing questionnaires to 60 respondents. The analysis technique used is multiple linear regression. The results of the research show that the variables administration costs, estimated value, ijarah costs, and product quality have a positive and significant effect on customer interest because ttable greater than tcount and the significance value is smaller than 0.05. Meanwhile, the late fine variable has a negative and insignificant effect on customer interest, this is proven by ttable smaller than tcount and the significance value is greater than 0.05.