Cahyono, Aris
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Suction Blister Skin Graft Cahyono, Aris; Ilona, Sri Esa; Sulaikha, Khalida Rieka; Mochtar, Moerbono
Cermin Dunia Kedokteran Vol 45, No 10 (2018): Muskuloskeletal
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (341.416 KB) | DOI: 10.55175/cdk.v45i10.591

Abstract

Skin blisters skin graft merupakan prosedur transplantasi epidermis menggunakan atap bula yang dibentuk dengan memberikan tekanan negatif pada kulit. Telah banyak modifikasi dilakukan untuk mempermudah dan mempercepat tindakan ini; meliputi alat, cara dan terapi lanjutan. Beberapa penyakit yang dapat diterapi dengan prosedur ini di antaranya vitiligo dan ulkus kronis.Skin blisters skin graft are epidermal transplantation procedure using the top of blisters produced by putting negative pressure on the skin. Many modifications have been made to facilitate and accelerate this procedure; including tools and methods. Diseases that can be treated with this procedure includes vitiligo and chronic ulcers.
The comparison of skin irritation level between topical cajeput oil and telon oil: A pilot study Ilona, Sri Esa; Cahyono, Aris; Ellistasari, Endra Yustin; Irawanto, Muh. Eko; Kariosentono, Harijono
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 2, No. 3
Publisher : UI Scholars Hub

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Abstract

Background: Cajuputi/Cajeput/Melalueca leucadendron oil is a type of essential oil, widely known and used by Indonesian for infants, children, and elderly. It is also included in telon oil compositions (±42%). Excessive application of cajeput oil and telon oil may lead to skin irritation. Methods: This randomized single-blind control trial was conducted with 10 subjects who met the inclusion criteria. Four areas with diameter of 10 mm each were made on the flexor surface of the upper arm. Area 1 was designated as negative control. Area 2 to 4 were pre-irritated with tape stripping for 40 ± 10 times using Nachitape®, followed by repeated open application test (ROAT) with cajeput oil, telon oil and alcohol (positive control). The skin irritation was examined in 15 minutes after each cycle by measuring transepidermal water loss (TEWL) using Tewameter® TM300 (Courage-Khazaka, Germany) and erythema using Mexameter® MDD4. Data were analyzed using One-way ANOVA with p<0.05 considered significance. Results: The average TEWL and erythema of cajeput oil (15.59; 345.42) were the highest compared to telon oil (12.63; 316.60), alcohol (13.87; 319.06) and negative control (7,48; 296.68). All treatment groups had significant differences in TEWL (p<0.000) and erythema (p<0.002) when compared to the negative control. However, cajeput oil showed the largest difference. Conclusion: Cajeput oil caused the most irritation compared to alcohol and telon oil. Therefore, it should be used with caution.