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All Journal MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan Medical and Health Journal
Fadlilah, Synta Haqqul
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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BEETROOT (Beta vulgaris L.) AND ITS POTENTIAL AS AN ANEMIA TREATMENT IN PREGNANCY Fadlilah, Synta Haqqul; Suhartomo, Dalri Muhammad; Yusan, Rizak Tiara; Yudhawan, Indra
Medical and Health Journal Vol 3 No 1 (2023): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2023.3.1.9070

Abstract

Anemia is one of the most common nutritional problems in pregnant women. It is defined as a condition in which the hemoglobin (Hb) level is lower than normal. The main cause of anemia in obstetrics is iron deficiency. To prevent this condition, the Government of Indonesia through the Ministry of Health made a rule by giving iron tablets to pregnant women at least 90 tablets during pregnancy (Kemenkes RI, 2022). However, some people are often bored with this pharmacological therapy due to the nausea and vomiting effect of the iron smell. Therefore, the development of alternative anemia therapy has been done to minimize those problems. One of the herbal ingredients that are being studied for its potential as anti-anemia in pregnancy is beetroot (Beta vulgaris L.). This research is included in the type of literature review. The selected literature is research articles published in the last 10 years (2013 to 2023). There are 10 articles that match the topic of study. A total of 7 publications demonstrated the effect of beetroot on anemia in pregnant women during the pregnancy period, and 2 articles in the post-partum period. A study performed in vivo experiments on pregnant female rats. Almost all of the studies did intervention by giving subjects beetroot juice. Only one study used beets as an intervention as ice cream. The results show that beetroot has the potential to prevent and treat anemia in pregnancy by increasing hemoglobin levels and the amounts of hematocrit. It contains a high level of folic acid which is important for normal cell and tissue growth. The iron content of beetroot also plays an essential role in the human body transporting oxygen to red blood cells, so it helps to cure anemia.
The Potential of Noni (Morinda citrifolia L.) as an Anti-Diabetic Fadlilah, Synta Haqqul; De Silva, Ghea; Suhartomo, Dalri Muhammad; Yusan, Rizak Tiara
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 11, No 1 (2024): February
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/magnamed.11.1.2024.83-96

Abstract

Background: Diabetes Mellitus (DM) is still a major health problem in the world today because the prevalence remains increasing. Type 2 diabetes is the most common type of diabetes, accounting for over 90% of all diabetes cases. This disease is characterized by insulin resistance, where the body cannot fully respond to insulin. As a result, glucose levels in the blood continue to increase (hyperglycemia). The main of Type 2 DM management is a healthy lifestyle. In addition, pharmacological therapy is also needed to keep blood glucose levels in diabetics under control. However, antidiabetic medicines can cause some side effects. Therefore, the development of alternative diabetes therapy has been done to minimize side effects. One of the herbal ingredients that are being studied for its potential as an anti-diabetic is noni (Morinda citrifolia L.).Objective: The aim of the study is to review and find out more about the potential of noni (Morinda citrifolia L.) as an anti-diabetic.Methods: This research is included in the type of literature review. The kinds of literature are English and Indonesian language research articles related to the topic searched by using database sources from ProQuest, PubMed, ScienceDirect, and Google Scholar. The research articles were published in the last 10 years (2012 to 2022). Results: There are 14 kinds of literature that match the topic of study. A total of 12 kinds of literature are in vivo studies on animals and 2 literature studies on humans. The result shows that noni has an antidiabetic effect by lowering blood glucose levels and improving other parameters. Parts of Noni that have the potential to control Type 2 DM are fruit and leaves, which can be in the form of extracts, juices, or fermented products. Further research is needed to evaluate the toxicity, the content of active compounds, and the expression of genes related to Type 2 DM for ensuring the mechanism of noni in controlling hyperglycemia. Human studies with more respondents are also needed to confirm the findings of existing studies. Conclusion: Noni has an antidiabetic effect by lowering blood glucose levels and improving other parameters. Based on human studies, noni fruit juice can serve as a suitable addition to the diet of Type 2 DM patients.
Co-Authors De Silva, Ghea Suhartomo, Dalri Muhammad Yudhawan, Indra Yusan, Rizak Tiara