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All Journal El-Hayah : Jurnal Biologi Bioinformatics and Biomedical Research Journal
Wardati, Fauchil
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Education Engineering Environmental Science Immunology & microbiology Medicine & Pharmacology

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Identification of Phytochemicals Compound On the Ethanol Extract ‎of Banana Peel Musa Balbisiana Colla “Kepok Putih” and Musa X ‎Corniculata Lour. “Tanduk”‎ Wardati, Fauchil; Fitriahani, Feby; Laily, Ainun ‎ Nikmati
El-Hayah : Jurnal Biologi Vol 8, No 1 (2020): EL-HAYAH (VOL 8, NO 1 SEPTEMBER 2020)
Publisher : Department of Biology Science and Technology Faculty UIN Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/elha.v8i1.11318

Abstract

Indonesia is the largest banana producer in Asia and each year continues to increase its production. The number of banana production in Indonesia reached 4,177,155 tons in 2003 and increased continuously to 6,373,533 tons in 2009. The abundance of banana peel is not comparable with the utilization of a banana peel in the society which has so far not been processed much apart from being animal feed. Two types of bananas that are often processed but the peels have not been optimally utilized yet are “kepok putih” and “tanduk”. Banana peel of “kepok kuning” extract contains alkaloids, flavonoids, quinones, saponins and tannins. However, the phytochemical compounds of banana peel “kepok putih” and “tanduk” have not been widely studied. Thus, this research aims to identify the phytochemical compounds from banana peel of “kepok putih” and “tanduk”. The extraction method which used in this experiment was the maceration method using 96 % ethanol solvent. Based on the test results, which may be obtained, it is known that the ethanol extract of banana peel “kepok putih” contains flavonoids, tannins,  alkaloids, while “tanduk” contains flavonoids, saponins, tannins, and alkaloids
Cytotoxicity Test on Breast Cancer Cell Lines T-47D treated with Pisang Kepok Peel Extract (Musa balbisiana) Wardati, Fauchil; Holil, Kholifah; Syarifah, Umaiyatus
Bioinformatics and Biomedical Research Journal Vol. 1 No. 3 (2018): Volume 1 Issue 3
Publisher : Future Science

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Abstract

Introduction: Utilization of natural ingredients such fruit as a breast cancer treatment agent is beginning to be widely studied by scientists. The goal is to reduce the side effects of chemotherapy agents. One of the potential natural ingredients as anticancer is Pisang Kepok peel (Musa balbisiana). This kind of banana contains various phytochemical compounds and high antioxidant activity that can induce cancer cell apoptosis. The purpose of this research is to know the IC50 value of Pisang Kepok peel extract thus can be known its potential as an anticancer agent. The lower of IC50 value is more cytotoxic. Method: This research is experimentally done by using CRD (Completely Randomized Design). The stages of this research are extraction and cytotoxic test (MTT assay). The extraction method was used maceration (ethanol 95%). The cytotoxic test was performed by giving Pisang Kepok unripe peel extract on the T-47D cell lines, then read the absorbance with ELISA reader at ? 595 nm and analyzed by SPSS Probit. Conclusions: Based on this results, it can be concluded that Pisang Kepok peel extract has moderate cytotoxic to T-47D cell lines, therefore indicate its potential as a candidate for breast cancer chemoprevention agents, especially at high concentrations (>250 ?g/mL).
Co-Authors Fitriahani, Feby Kholifah Holil Laily, Ainun ‎ Nikmati Umaiyatus Syarifah