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All Journal Jurnal Sains dan Teknologi Journal of Functional Food and Nutraceutical
Kartawidjajaputra, Felicia
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Agriculture, Biological Sciences & Forestry Computer Science & IT Education Nursing

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ANALYSIS OF PHYTOCHEMICAL SUBSTANCE AND THE EFFECT OF CANG SALAK TEA (CST) DIET TO LIPID PROFILE ON HYPERLIPIDEMIC RAT Karta, I Wayan; Burhannuddin, Burhannuddin; Kartawidjajaputra, Felicia
JST (Jurnal Sains dan Teknologi) Vol 10, No 2 (2021)
Publisher : Universitas Pendidikan Ganesha

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (242.027 KB) | DOI: 10.23887/jst-undiksha.v10i2.39302

Abstract

The bark of Sibetan snakefruit (Salacca zalacca) and sappan wood (Caesalpinia sappan L.) are combined into the product of Cang Salak Tea (CST). This tea is expected to be useful for diseases associated with dyslipidemia. The purpose of this study was to examine the secondary metabolites in CST and to determine the effect of CST treatment on the lipid profile of total cholesterol (TC), triglyceride (TG), HDL, and LDL level. Wistar rats were divided into three groups: control group (K), hyperlipidemic rats group given CST (P1), and hyperlipidemic rat group without CST treatment. Group P1 was given CST as much as 1.2 mL per day for 4 weeks. CST contains alkaloid, flavanoid, tannin, phenol, and saponine. Flavonoid level about 81.026 ppm; tannin 525.706 ppm, IC50 177.689 ppm, and phenol 622.7844 ppm. There were significant differences in the lipid profile of K and P1 with P2. CST treatment to hyperlipidemic rats can reduce total cholesterol and normalize level of TG, HDL, and LDL. The active substance in CST has role in lipid metabolism, so it can improve the lipid profile of hyperlipidemic rats.
Cholesterol-lowering Effect of Soy Nuts and Tempeh on Hypercholesterolemic Subjects Zulaikha, Hermawati Nur; Dijaya Muliadi, Rendy; Kartawidjajaputra, Felicia; Antono, Lina
Journal Akademik Universitas Swiss German Vol. 4 No. 2 (Feb 2023)
Publisher : Swiss German University & Perhimpunan Penggiat Pangan Fungsional dan Nutrasetikal Indonesia (P3FNI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33555/jffn.v4i2.100

Abstract

Exploration towards food with cholesterol-lowering property would be beneficial to reduce the incidents of cardiovascular caused by increasing number of people with hypercholesterolaemia. As much as 42 participants with total cholesterol (TC) levels ≥4.92 mmol/L were studied in a three-arms parallel intervention trial. As much as 72g soy nuts and 66g tempeh were consumed daily (25g soy protein/day) for six weeks, while control group was not given any sample. TC level and body composition were measured before and after the treatment for all groups. In soy nuts group, lower TC level was observed (-0.85±0.82 mmol/L, p<0.05) compared to the control group. Meanwhile in tempeh group, non-significant lower TC level was also observed (-0.40±1.19 mmol/L). Differences in body composition parameters were also measured and resulted in significant lower body weight, fat, and visceral fat in soy nuts group (p<0.05) while in tempeh group, only body weight and waist circumference were significantly decreased (p<0.05). This study suggested that daily consumption of soy nuts and tempeh containing 25g soy protein for six weeks showed a tendency to lower TC levels in hypercholesterolaemic-Indonesian participants. A more significant effect might be observed in subject with higher TC levels; and thus, further study is encouraged.
Co-Authors Antono, Lina Burhannuddin Dijaya Muliadi, Rendy I Wayan Karta Zulaikha, Hermawati Nur