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Tanojo, Natalia
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Immunology & microbiology Public Health

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Journal : Berkala Ilmu Kesehatan Kulit dan Kelamin

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The use of dermoscope to differentiate Pityrosporum folliculitis and Acne vulgaris Tanojo, Natalia; Anggraeni, Sylvia
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 3 (2023): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.3.2023.119-225

Abstract

Background: Both Pityrosporum folliculitis (PF) and Acne vulgaris (AV) are chronic inflammation of pilosebaceous follicle but with different etiology. The similar findings may lead to misdiagnosis that worsen symptoms, especially if PF is treated with antibiotics meant for AV. A simple KOH examination helps to differentiate PF and AV is not always readily available in clinical setting.Purpose: to find an alternative, practical tool to confirm the diagnose of PF and AV.Review: Dermoscope is a handheld microscope equipped with 10x magnification and a light source for microscopic visualization of the subcutaneous structures. The monomorphic lesions in PF appear as hypopigmented, round lesions with coiled/looped hair in the center. Dermoscope image of AV varies according its polymorphic manifestations. A non-inflammatory AV shows a yellow-brown blockage in the center while inflammatory AV is depicted as round, whitish lesions with thin brownish borders and erythematous marginal lesions. Pustular AV appears as raised lesions with indistinct borders and white or yellowish in the middle and surrounding reddish borders.Conclusion: Dermoscope help to see skin structures invisible to naked eyes and thus, help to diagnose PF and AV.
The Demography, Clinical Characteristics, and White Blood Analysis of Leprosy Reactions in Multibacillary Leprosy: A Retrospective Study Tanojo, Natalia; Damayanti, Damayanti; Utomo, Budi; Ervianti, Evy; Murtiastutik, Dwi; Cita Rosita Sigit Prakoeswa; Listiawan, M. Yulianto
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 3 (2021): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.3.2021.187-193

Abstract

Background: Leprosy is a neglected tropical disease caused by chronic granulomatous infection of Mycobacterium leprae. Indonesia ranks third in new case findings, with 84% of the case being multibacillary (MB) leprosy. MB leprosy cases have a higher risk of leprosy reactions and physical disabilities that decrease quality of life. Purpose: To determine the demographic, clinical characteristics, and white blood analysis of newly diagnosed MB leprosy patients, especially concerning leprosy reactions. Methods: This is a descriptive retrospective study with a cross-sectional design that describe the following data: domicile, gender, age, treatment status, disabilities, body mass index (BMI); bacterial index (BI), morphological index (MI), white blood cell (WBC) and differential counts, and thrombocyte count. Result: This study included 176 adult MB cases, predominantly male aged 20–39 years old with average BMI, lived in Surabaya with negative history of multi-drug therapy, disability, BI, nor MI. The grade 2 disability (G2D) percentage in this study setting than in Indonesia (10.7% vs. 6.43%). The WBCs, especially neutrophil count, was higher in T2R group. Monocyte and lymphocyte counts were relatively similar. There was an increase in thrombocyte count in leprosy reaction groups. Conclusion: MB leprosy in the endemic area, which is more commonly found in productive-aged male, displayed higher G2D than global Indonesia population. Thus denotes the importance of active case findings. The difference in blood analysis characteristics between MB leprosy with and without reactions may serve as the foundation for future study.
Co-Authors Anggraeni, Sylvia Budi Utomo Cita Rosita Sigit Prakoeswa Damayanti Damayanti Dwi Murtiastutik Evy Ervianti M. Yulianto Listiawan