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All Journal Pharmascience Jurnal Farmasi Sains dan Komunitas (JFSK)
Adisaputra, Arya Dibyo
Pharmacy Study Program, Mathematics And Natural Sciences Faculty, Universitas Tadulako
Medicine & Pharmacology

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COST AND EFFECTIVENESS OF ATYPICAL-ATYPICAL ANTIPSYCHOTIC COMBINATIONS AND ATYPICAL-TYPICAL ANTIPSYCHOTIC COMBINATIONS IN PATIENTS OF PSYCHOTIC DISORDERS IN INSTALLATION OF EMERGENCY IN GRHASIA MENTAL HOSPITAL, YOGYAKARTA Arya Dibyo Adisaputra; Endang Darmawan; Arum Siwinarni
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 18, No 2 (2021)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (218.188 KB) | DOI: 10.24071/jpsc.002453

Abstract

Psychotic disorders create a burden on the government, family, and society because of decreasing patient productivity. The use of atypical-atypical and atypical-typical antipsychotic combinations is one of the most commonly used combinations for patients with psychotic disorders. The study was conducted to determine the average total cost and effectiveness of the therapy measured by the difference in PANSS-EC pre-post scores during intensive care. The study was conducted prospectively to analyse the total cost and effectiveness of the therapy using combinations of antipsychotics in psychotic disorders patients. The measured costs include the cost of nursing classes, laboratory, medical treatment, doctor's visit, and antipsychotic. The effectiveness is measured by the difference in PANSS-EC pre-post scores. As many as 32 treated patients with psychotic disorders met the inclusion criteria. The average cost of atypical-typical antipsychotic combination group (Rp1,184,043) was higher than atypical atypical antipsychotic combination group (Rp1,115,829). The effectiveness of the therapy was represented by the value of the difference between the PANSS-EC pre and post scores, which in this research yielded a mean of 7,125 for atypical-atypical antipsychotic combinations and 8,375 for atypical-typical antipsychotic combinations. In conclusion, there is a difference in the total average cost and effectiveness of the therapy. There is a difference between PANSS-EC pre and post scores during the time period from intensive room to quiet room in atypical-typical antipsychotic combinations compared with atypical-atypical antipsychotic combinations.
Cost Effectiveness Analysis Antibiotik Profilaksis pada Pasien Apendisitis di RSUD Anutapura Palu Tahun 2018 Khusnul Diana; Muzna Muzna; Muhamad Rinaldhi Tandah; Arya Dibyo Adisaputra
Jurnal Pharmascience Vol 9, No 1 (2022): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v9i1.11005

Abstract

Apendisitis adalah peradangan akibat infeksi pada apendiks yang mana memerlukan penanganan berupa pembedahan untuk mencegah komplikasi perlu dilakukannya apendiktomi atau pengangkatan apendiks. Apendiktomi merupakan operasi bersih kontaminasi dan termasuk dalam kategori tinggi untuk diberikan antibiotik profilaksis. Tujuan penelitian ini adalah untuk mengetahui manakah penggunaan antibiotik profilaksis yang paling cost-effective pada pasien apendisitis di RSUD Anutapura Palu. Jenis penelitian ini adalah penelitian deskriptif dengan pengambilan data secara retrospektif. Penelitian ini dilakukan untuk menganalisis efektivitas biaya (Cost-Effectiveness Analysis) antibiotik profilaksis pada pasien apendisitis dengan melihat parameter penurunan suhu tubuh. Subyek penelitian yaitu 69 pasien rawat inap yang memenuhi kriteria inklusi dan eksklusi. Hasil penelitian menunjukan terdapat pasien yang menggunakan terapi antibiotik tunggal sebanyak 35 pasien (50,72%), kombinasi 2 antibiotik 27 pasien (39,13%) dan kombinasi 3 antibiotik 7 pasien (10,14%). Rata-rata total biaya medis langsung penggunaan antibiotik tunggal Rp. 7.430.971, kombinasi 2 antibiotik Rp. 11.236.020, kombinasi 3 antibiotik Rp. 12.321.345. Berdasarkan perhitungan ACER, diperoleh antibiotik yang memiliki  biaya rendah adalah antibiotik tunggal seftriakson dengan nilai Rp. 159.199/unit suhu. Kata Kunci: Apendisitis, Antibiotik Profilaksis, Apendiktomi, Cost-Efffectiveness Analysis, Direct Medical Cost Appendicitis is inflammation due to infection of the appendix which requires treatment in the form of surgery to prevent complications, it is necessary to do an appendectomy or removal of the appendix. Appendectomy is a clean operation of contamination and is included in the high category for prophylactic antibiotics. The purpose of this study was to determine which use of prophylactic antibiotics was the most cost-effective in appendicitis patients at Anutapura Hospital Palu. This type of research is descriptive research with retrospective data collection. This study was conducted to analyze the cost-effectiveness (Cost-Effectiveness Analysis) of prophylactic antibiotics in appendicitis patients by looking at the parameters of decreasing body temperature. The research subjects were 69 hospitalized patients who met the inclusion and exclusion criteria. The results showed that there were 35 patients (50.72%), a combination of 2 antibiotics (39.13%) and a combination of 3 antibiotics 7 patients (10.14%). The average total direct medical cost of using a single antibiotic is Rp. 7,430,971, a combination of 2 antibiotics Rp. 11,236,020, a combination of 3 antibiotics Rp. 12,321,345. Based on ACER calculations, the antibiotic that has a low cost is the single antibiotic ceftriaxone with a value of Rp. 159,199 /unit temperature.
Co-Authors Arum Siwinarni Endang Darmawan Khusnul Diana Muhamad Rinaldhi Tandah Muzna Muzna