Garuda - Garba Rujukan Digital

p-Index From 2019 - 2024

0.92

P-Index

This Author published in this journals

All Journal Medical Journal of Indonesia Berkala Ilmu Kesehatan Kulit dan Kelamin Journal of General Procedural Dermatology and Venereology Indonesia

Sitohang, Irma Bernadette Simbolon

Department Of Dermatology And Venereology Faculty Of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital

Author-ID : 2155420

Immunology & microbiology Medicine & Pharmacology Public Health

Published : 5 Documents Claim Missing Document

Claim Missing Document

Articles

The susceptibility of pathogens associated with acne vulgaris to antibiotics Sitohang, Irma Bernadette Simbolon; Fathan, Hafizah; Effendi, Evita; Wahid, Mardiastuti
Medical Journal of Indonesia Vol 28, No 1 (2019): March
Publisher : Faculty of Medicine Universitas Indonesia

BACKGROUND Acne vulgaris is a pilosebaceous disorder. Bacterial activity and inflammation both influence acne formation. Antibiotics suppress the bacterial activities and elicit anti-inflammatory effects. The overuse of antibiotics may lead to resistance in bacteria. This study was aimed to provide an overview of bacteria that may cause acne and determine their susceptibility to antibiotics.METHODS This was a cross-sectional study sampling from 93 patients with acne in Ciptomangunkusumo Hospital. Comedones were extracted and cultured on Brucella blood agar, under aerobic and anaerobic conditions at 35oC for 24–48 hours. Bacterial identification was performed using Vitek®, and susceptibility test using E-test. Data interpretation was based on the Clinical and Laboratory Standards Institute 2015.RESULTS Staphylococcus epidermidis (50.5%), Propionibacterium acnes (11.0%), and Staphylococcus aureus (7.7%) were identified. Bacteria were not found in 69.2% and 1.1% of samples in anaerobic and aerobic cultures, respectively. P. acnes was susceptible to doxycycline (100%) and minocycline (100%), while 10% was resistant to erythromycin, clindamycin, and tetracycline. S. epidermidis was susceptible to minocycline (100%); but resistant to erythromycin (65.2%), clindamycin (52.2%) and tetracycline (32.6%). The susceptibility of S. epidermidis to doxycycline was 89.1%, which was lower than that of P. acnes (100%). S. aureus was found to be sensitive to minocycline (100%), doxycycline (71.4%), clindamycin (71.4%), and tetracycline (71.4%); but it was resistant to erythromycin (42.9%).CONCLUSIONS Doxycycline and minocycline showed 100% effectiveness for P. acnes. The isolated bacteria were more susceptible to doxycycline compared to tetracycline. The use of clindamycin and erythromycin needs to be limited as most S. epidermidis isolates were resistant to both.

Association of zinc intake & serum zinc levels with acne severity Chintia Otami; Dian Novita Chandra; Irma Bernadette Sitohang
Journal of General - Procedural Dermatology and Venereology Indonesia Vol 4, No 2 (2020): June 2020
Publisher : Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Background: Recent studies have suggested the relationship between diet and acne, and zinc plays a role through its anti-inflammatory mechanism. This study aimed to determine the association between zinc intake and serum zinc levels with acne severity.Methods: A comparative cross-sectional study was conducted to assess the difference in zinc intake and serum zinc levels with acne severity based on Indonesian Acne Expert Meeting (IAEM) criteria. Sixty patients with acne in Dr. Cipto Mangunkusumo General Hospital were selected. The effect of zinc intake on acne severity was analyzed via unpaired T test, whereas the effect of serum zinc levels on acne severity was examined with Mann–Whitney test. Data were further evaluated using SPSS 20.0.Results: Zinc intake in all the subjects was below the Indonesian recommended daily allowance, and the mean of zinc intake and serum zinc levels in the mild acne group was higher than that of the moderate–severe acne group. The zinc intake significantly differed between the mild and moderate–severe acne groups (p < 0.01). Likewise, serum zinc levels significantly varied between mild and moderate–severe acne group (p = 0.048).Conclusion: Although this study showed a significant difference between zinc intake and serum zinc levels with the severity of acne vulgaris, further follow-up studies should be performed to assess zinc for acne vulgaris therapy.Keywords: zinc intake, serum zinc level, acne severity

Validity and reliability of melasma quality of life scale questionnaire in Bahasa Indonesia for female patients Rubby Aditya; Aida S.D. Hoemardani; Irma Bernadette. S Sitohang; Levina Chandra; Rajesh Balkrisnan
Journal of General - Procedural Dermatology and Venereology Indonesia Vol 4, No 2 (2020): June 2020
Publisher : Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Background: At present, there is no questionnaire in Bahasa Indonesia to assess the quality of life of female patients with melasma. The aim of this study is to adapt the existing English questionnaire, MELASQOL, into Bahasa Indonesia, and to assess its validity and reliability. Methods: This is a cross-sectional study consisting of two stages. The initial stage is cross-cultural and language adaptation. The final stage is the validity and reliability test. The original MELASQOL questionnaire is in English and is adapted into Bahasa Indonesia according to the cross-cultural and language adaptation guidelines. The subjects were recruited from two sites, The Cipto Mangunkusumo Hospital and a factory in Tangerang. A construct validity method was used for the validity analysis. Cronbach’s α was used for internal reliability analysis.Results: The initial stage involved 30 subjects, and 32 subjects were involved with the final stage. The validity of The MELASQOL Bahasa Indonesia was calculated by the item-total score. The correlation coefficient is 0.712–0.935. Its reliability was calculated by the Cronbach α score is 0.962.Conclusions: MELASQOL Bahasa Indonesia is a valid and reliable instrument for assessing the quality of life of female patients with melasma in Indonesia. Keywords: MELASQOL, Bahasa Indonesia, quality of life, validity, reliability.

Case series of primary psychiatric skin disorders with multi-disciplinary approach Lusiana Lusiana; Rizky Lendl Prayogo; Shannaz Nadia Yusharyahya; Irma Bernadette S. Sitohang; Kusmarinah Bramono
Journal of General - Procedural Dermatology and Venereology Indonesia Vol 4, No 2 (2020): June 2020
Publisher : Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Background: The incidence of psychodermatologic diseases, a group of skin abnormalities associated with psychosomatic factor, are increasing recently. About 20-40% patients with skin symptoms have concurrent psychiatric problems which are often difficult to diagnose and treat. The new classification of primary psychiatric skin disorders are delusional disorders, obsessive-compulsive and related disorders, and factitious disorders. This classification could be used for effective treatment in each patient which involves multi-disciplinary approach, including dermatology, psychiatry and other discipline if necessary. Case Illustration: The first case was a 39-year-old unmarried female, with anemia and dermatitis artefacta occurred as wound due to blade cuts. Patient was with schizoaffective depressive type and was not under regular treatment. The second case was a 61-year-old male referred with unresolved prurigo nodularis for the past 30 years. After in-depth assessment, there were delusional parasitosis and neurotic excoriations disorders. The third patient was a 50-year-old female admitted with recurrent ulcer on her face. She was aware that the lesions were intentionally manipulated by her own fingers when she was depressed. Discussion: All patients were classified as primary psychiatric skin disorders with varied skin manifestations. Symptoms usually occurred when the patient was in the depression state or low compliance for the psychotropic drugs. Patients generally had poor insight and refused to be associated with psychiatric factors. Dermato-venereologists are expected to conduct early detection and treat this disease. Conclusion: It is important to approach psychocutaneous disease in multi-disciplinary manner, especially with the psychiatrist. Keywords: psychodermatologic, dermatitis artefacta, neurotic excoriations, delusion of parasitosis

Angka Kejadian Hiperpigmentasi Pasca Inflamasi pada Pasien Akne Vulgaris Sedang Tipe Kulit IV-V yang Diterapi Gel Benzoil Peroksida 2,5% Uji Klinis, Acak, Buta Ganda Irma Bernadette S. Sitohang; Putu Siska Virgayanti; Shannaz Nadia Yusharyahya
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 31 No. 3 (2019): DESEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Latar belakang: Akne vulgaris (AV) merupakan peradangan kronis folikel pilosebasea dengan manifestasi klinis berupa komedo, papul, pustul, nodus dan pseudo kista yang bersifat swasirna. AV digolongkan atas tiga kategori, yaitu akne vulgaris ringan (AVR), sedang (AVS) dan berat (AVB). Rekomendasi Global Alliance dalam penanganan AVS meliputi antibiotik, asam retinoat, dengan atau tanpa benzoil peroksida (BPO). Kombinasi antibiotik dan BPO direkomendasikan untuk mengatasi masalah tersebut meskipun pada tipe kulit IV-V, hiperpigmentasi pasca inflamasi merupakan masalah yang sering dikeluhkan pada penggunaan BPO. Tujuan: Membandingkan efektivitas, efek samping dan kejadian hiperpigmentasi pasca inflamasi (HPI) pada penggunaan BPO sebagai paduan terapi lini pertama AVS pada tipe kulit IV-V Fitzpatrick. Metode: Penelitian analitik dengan desain uji klinis acak tersamar ganda membandingkan dua sisi wajah yang diberikan paduan terapi lini pertama. Sisi wajah perlakuan diberikan gel BPO 2,5% sedangkan kelompok kontrol gel plasebo. Hasil: Pada minggu ke-2,4,6,8 didapatkan penurunan persentase total lesi sebesar 51,47%, 71%, 75%, 82,84% pada kelompok BPO dan 30%, 53,75%, 62,28, 71% pada kelompok plasebo (p<0,001) Efek samping dan kejadian HPI pada minggu ke 2,4,6 dan 8 tidak berbeda bermakna. Simpulan: Penggunaan BPO sebagai bagian dari paduan terapi lini pertama AVS lebih efektif, tidak meningkatkan efek samping ataupun kejadian HPI.

Co-Authors Aida S.D. Hoemardani Chintia Otami Dian Novita Chandra Effendi, Evita Fathan, Hafizah Kusmarinah Bramono Levina Chandra Lusiana Lusiana Putu Siska Virgayanti Rajesh Balkrisnan Rizky Lendl Prayogo Rubby Aditya Shannaz Nadia Yusharyahya Shannaz Nadia Yusharyahya Wahid, Mardiastuti

Title

Found 5 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 5 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 5 Documents
Search