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Journal : Nusantara Medical Science Journal

Right Ventricle Free Wall Longitudinal Strain in Cancer Patients Following Chemotherapy Ghaznawie, Aussie Fitriani; Muzakkir, Akhtar Fajar; Fathlina, F.; Mappahya, Ali Aspar; Alkatiri, Abdul Hakim; Zainuddin, Andi Alfian; Prihantono, Prihantono
Nusantara Medical Science Journal Volume 8 Issue 1, January - June 2023
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v8i1.26648

Abstract

Introduction: The survival rate of cancer patients was high due to chemotherapy, but it can cause cardiotoxicity and increase morbidity and mortality. Most studies on cancer therapy-related cardiac dysfunction (CTRCD) focus more on the left ventricle. This study assesses chemotherapy's effect on the right ventricle, namely the right ventricle free wall longitudinal strain (RVFWLS). Methods: This study is a prospective cohort conducted from January to December 2022 on thirty-four cancer patients undergoing chemotherapy at Dr Wahidin Sudirohusodo Hospital Makassar. The RVFWLS was assessed before and after chemotherapy using echocardiographic. Result: The RVFWLS value after one cycle chemotherapy decreased compared pre-chemotherapy (4.40±4.84; p=0.001). Conclusion: The effect of chemotherapy is a decrease the RVFWLS value after the first cycle of chemotherapy. It should be considered for echocardiographic evaluation, especially the RVFWLS value every cycle of chemotherapy.