Andi Alfian Zainuddin
Bagian Ilmu Kesehatan Masyarakat/Ilmu Kedokteran Komunitas Fakultas Kedokteran Universitas Hasanuddin

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CORRELATION BETWEEN SERUM CALCIUM AND PHOSPHATE WITH CORONARY ARTERY CALCIUM SCORES ON CARDIAC MSCT EXAMINATION Kai, Rosita; Murtala, Bachtiar; Zainuddin, Andi Alfian; Amin, Muzakkir; Ilyas, Muhammad
Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga Vol 15, No 2 (2019): December 2019
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (218.617 KB) | DOI: 10.22219/sm.Vol15.SMUMM2.9970

Abstract

Increased serum calcium and phosphate associated with cardiovascular disease in patients with chronic kidney disease, but research on the relationship between coronary artery calcium scores with serum calcium and phosphate in individuals with normal kidney function is lacking. We explore the relationship of serum calcium and phosphate levels with coronary atherosclerosis as assessed by cardiac Multislice Computed Tomography (MSCT) in individuals with normal kidney function. This study aims to assess the correlation of calcium level scores on cardiac MSCT examination with serum calcium and phosphate levels, and assess the association with risk factors for coronary heart disease. This study was a cross-sectional study of 40 subjects who underwent cardiac MSCT examination with normal kidney function, at RSUP Dr. Wahidin Sudirohusodo Makassar during the March-July 2019 period. The results showed an correlation between coronary artery calcium scores with calcium and serum phosphate (serum calcium r = 0.67, serum phosphate r = 0.53, p <0.05).
Correlation between Ultrasound Findings of Uric Acid Precipitate in MTP I and Acute Gout Flare in Gouty Arthritis SUSANTI, Elys; Ilyas, Muhammad; Idris, Nurlaily; Zainuddin, Andi Alfian; Murtala, Bachtiar; HP, Faridin
Jurnal Kedokteran Brawijaya Vol 31, No 1 (2020)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2020.031.01.7

Abstract

Acute gout flare is the most common manifestation of gouty arthritis that intermittently occurs with severe pain in the joints due to interactions between monosodium urate crystals (MSU) and the surrounding tissues. The most common predilection is the metatarsophalangeal joint (the 1st MTP). Ultrasound examination is a modality that can be used to visualize MSU crystal precipitates in and around joints. This study aimed to determine the correlation between the findings of the MSU crystal precipitate on the 1st MTP using ultrasound with the occurrence of acute gout flare in gout patients. This study was an analytical observational study with a cross-sectional method. The samples were 41 patients with a history of previous acute flares and in the intercritical phase when participating in the study. Examinations of ultrasound on the 1st MTP and random serum uric acid level were performed. Evaluations were carried out on both of the 1st MTPs to assess the shape of the MSU crystalline precipitate, namely Double Contour Sign (DCS), aggregate, and tophus. Each sample was evaluated within five days to assess the presence or absence of an acute flare. The diagnostic tests used were the Chi-Square Test and the Fischer Exact Test with a significance value of p <0.05. The results showed the images of DCS were seen in 20 samples with 9 (45%) samples experiencing acute flare (p <0.05), while in 21 samples where no DCS were found, all did not experience any flare. Findings of aggregate and tophus were rarely found, 7.3% and 4.9%, respectively. In this study, the finding of DCS precipitates using ultrasound has a significant correlation to the emergence of acute flare and is a significant form of precipitate findings in this study, whereas aggregate and tophus precipitates are difficult to determine.
Analysis of Lamina Papyracea Area and Ethmoid Sinus Volume in Indonesian Patients Undergoing Paranasal Sinus CT Scan Wahyuni, Wahyuni; Idris, Nurlaily; Muis, Mirna; Zainuddin, Andi Alfian; Perkasa, Muhammad Fadjar; Ilyas, Muhammad
Jurnal Kedokteran Brawijaya Vol 31, No 1 (2020)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2020.031.01.6

Abstract

Of the rhinosinusitis (CRS) patients, half of whom require surgical intervention. Functional endoscopic sinus surgery (FESS) is a standard treatment of CRS and sinonasal polyposis. Orbito-ocular complications can occur during FESS. The lamina papyracea (LP) is the weakest point of the medial wall of the orbit. The variability in the size and shape of the paranasal sinuses is important in the FESS procedure. The ethmoid sinus is the most complex paranasal sinuses. Preoperative evaluation using computed tomography (CT) is mandatory for all patients undergoing FESS. This study aimed to determine the lamina papyracea area and ethmoid sinuses volume in patients who underwent a CT scan of paranasal sinuses. This study was a descriptive study on 103 patients who underwent a CT scan of paranasal sinuses in the Radiology Department of Hasanuddin University General Hospital, Makassar, from January to August 2019. The lamina papyracea area and ethmoid sinus volume were measured based on age and gender. The results showed that the average of lamina papyracea size and ethmoid sinus volume was greater in males than in females. There was a correlation between age and posterior height of left lamina papyracea (p=0.02), but no correlation between ethmoid sinuses volume and age.
Hubungan Shear Wave Elastography Ginjal dengan Estimated Glomerular Filtration Rate pada Pasien Penyakit Ginjal Kronik Arif, Asnita; Idris, Nurlaily; Murtala, Bachtiar; Zainuddin, Andi Alfian; Asriyani, Sri; Kasim, Hasyim
Jurnal Kedokteran Brawijaya Vol 30, No 4 (2019)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2019.030.04.10

Abstract

Penyakit ginjal kronik (PGK) merupakan masalah kesehatan global dengan biaya ekonomi tinggi pada sistem kesehatan sehingga dibutuhkan modalitas pencitraan klinis non invasif untuk mendeteksi penyakit ginjal pada stadium awal. Shear wave elastography (SWE) merupakan pemeriksaan imaging untuk menilai tingkat keparahan dari perubahan morfologi kronik ginjal berdasarkan pengukuran elastisitas kortex. Penelitian ini bertujuan mengetahui hubungan antara SWE dengan estimated glomerular filtration rate (eGFR) sehingga SWE dapat direkomendasikan untuk deteksi dini tingkat keparahan penyakit ginjal kronik.  Penelitian ini dilakukan di bagian Radiologi Rumah Sakit Umum Pusat Dr. Wahidin Sudirohusodo Makassar dari bulan September 2018 sampai dengan Februari 2019. Desain penelitian yang digunakan adalah observasional dengan rancangan potong lintang. Sampel penelitian sebanyak 118 sampel yang terdiri dari 71 sampel dengan penyakit ginjal kronik dan 47 sampel normal. Pemeriksaan ultrasonografi yang dilakukan dengan metode SWE untuk mengukur shear wave velocity (SWV) pada kedua ginjal dengan tiga kali pengukuran pada kortex ginjal. Nilai median dari SWV pada kedua ginjal dihubungkan dengan eGFR. Data dianalisis dengan uji korelasi Spearman. Hasil penelitian menunjukkan bahwa nilai median SWV pada kelompok sampel normal adalah 2,02±0,32m/s pada ginjal kanan  2,01±0,32m/s pada ginjal kiri yang cenderung menurun dengan bertambahnya  usia. Terdapat korelasi positif yang signifikan antara nilai SWV pada ginjal kanan dan kiri dengan eGFR, dengan arah korelasi positif (p<0,0001). Pada penelitian ini, terdapat pula korelasi negatif yang signifikan antara tekanan darah dan proteinuria dengan eGFR maupun dengan SWV pada pasien penyakit ginjal kronik.
Prediksi Prognosis Penderita Trauma Kapitis Berdasarkan Gambaran CT scan Kepala Husnah, Kurniawati; Murtala, Bachtiar; Asriyani, Sri; Zainuddin, Andi Alfian; Mustamir, Nasrullah; Latief, Nikmatia
Jurnal Kedokteran Brawijaya Vol 30, No 4 (2019)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (498.337 KB) | DOI: 10.21776/ub.jkb.2019.030.04.12

Abstract

Trauma kapitis memiliki penyebab, patologi, tingkat keparahan dan prognosis yang berbeda-beda sehingga diperlukan prediktor terpercaya untuk menilai luaran pasien. CT scan berperan penting dalam mengevaluasi kerusakan struktural pada fase akut trauma kapitis. Penelitian ini bertujuan menilai gambaran CT scan kepala dalam memprediksi prognosis penderita trauma kapitis. Penelitian ini merupakan penelitian retrospektif terhadap 444 penderita trauma kapitis ringan sampai berat yang dilakukan pemeriksaan CT scan kepala di RSUP Dr. Wahidin Sudirohusodo Makassar selama periode Januari-Juni 2018. Peneliti mengidentifikasi gambaran CT scan yang berpengaruh terhadap mortalitas pasien. Hasil penelitian menunjukkan bahwa status sisterna basalis (compressed, OR=31.690, absent, OR=11.092, p<0.0001), midline shift (OR=2.889, p<0.0001), dan pendarahan subarachnoid atau intraventrikel (OR=6,977, p<0.0001) merupakan prediktor independen mortalitas penderita trauma kapitis.
Korelasi antara Derajat Dehidrasi Menurut WHO dengan Rasio Vena Cava Inferior/Aorta Abdominal Menggunakan Ultrasonografi pada Anak Penderita Diare Herman, Teddy Marzuki; Murtala, Bachtiar; Latief, Nikmatia; Asriyani, Sri; Zainuddin, Andi Alfian; Ganda, Idham Jaya
Majalah Kesehatan Pharmamedika Vol 12, No 1 (2020): JUNI 2020
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/mkp.v12i1.1600

Abstract

Penelitian ini bertujuan menilai hubungan antara derajat dehidrasi menurut WHO dengan rasio vena cava inferior / aorta abdominal berdasarkan ultrasonografi pada anak penderita diare. Penelitian ini merupakan penelitian cross sectional terhadap 46 anak penderita diare yang masuk ke IGD pediatrik RSUP Dr. Wahidin Sudirohusodo Makassar dari bulan Oktober 2018 sampai Desember 2018. Penilaian derajat dehidrasi menurut WHO dilakukan oleh dokter anak sesaat setelah dilakukan pemeriksaan ultrasonografi untuk mengukur rasio vena cava inferior/aorta abdominal. Hasil penelitian menunjukkan terdapat korelasi kuat antara derajat dehidrasi menurut WHO dengan rasio IVC/aorta abdominal (p0,001, r=-0,637). Semakin berat derajat dehidrasi menurut WHO, semakin rendah rasio IVC/aorta abdominal.
Penyerupa dan Penyerta Tuberkulosis Paru yang Terdiagnosis Berdasarkan Gambaran CT-scan Toraks Pada Rumah Sakit Rujukan Tersier Bachtiar, Nur Amelia; Asriyani, Sri; Murtala, Bachtiar; Latief, Nikmatia; Djaharuddin, Irawaty; Zainuddin, Andi Alfian
Majalah Kesehatan Pharmamedika Vol 12, No 2 (2020): DESEMBER 2020
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/mkp.v12i2.1747

Abstract

Latar belakang: Sistem rujukan berjenjang dapat mempengaruhi karakteristik lesi pada CT-scan toraks pasien terduga tuberkulosis (TB) paru pada rumah sakit rujukan tersier. Hal ini dapat menyamarkan keberadaan penyerupa dan penyerta TB paru. Metode Penelitian: Sampel adalah pasien yang terdiagnosis TB paru oleh ahli radiologi pada periode Oktober 2018 hingga Juni 2019. Analisis Chi-square dilakukan untuk menguji kesesuain 12 karakteristik CT-scan toraks (Konsolidasi, kavitas, tree-in-bud, fibrokalsifikasi, air-bronchogram-sign, lesi noduler, efusi pleura, atelektasis, bercak infiltrat, lymphadenopathy, bronchiectasis, ground glass opacity) dengan diagnosis akhir klinisi. Pencatatan penyerupa dan penyerta TB dilakukan setelah diagnosis akhir ditegakkan. Hasil: Dari 137 sampel, hanya 61 (44.5%) pasien yang terdiagnosis sebagai TB paru aktif, 38 (27.7%) terdiagnosis sebagai bekas TB paru dan 38 (27.7%) lainnya terdiagnosis sebagai penyakit paru bukan tuberkulosis. Dari 12 variabel yang dievaluasi, karakteristik yang sesuai dengan diagnosis klinisi adalah tree-in-bud (p = 0.019) dan lymphadenopathy (p = 0.039). Penyakit penyerupa dan penyerta terbanyak adalah tumor paru dan infected bronchiectasis. Simpulan: Gambaran CT-scan pasien TB paru sangat beragam pada rumah sakit rujukan tersier. Diperlukan ketelitian ahli radiologi dan kerja sama yang baik dengan klinisi untuk mendeteksi berbagai kemungkinan diagnosis yang dapat menyerupai dan menyertai TB paru
Spatial Distribution of Drug-Resistant Tuberculosisin Makassar City, South Sulawesi Province, Indonesia Zainuddin, Andi Alfian; Soma, Andang Suryana; Kasim, Muhammad Firdaus; Ramadany, Sri; Djaharuddin, Irawati
KEMAS: Jurnal Kesehatan Masyarakat Vol 18, No 2 (2022)
Publisher : Department of Public Health, Faculty of Sport Science, Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v18i2.36436

Abstract

This study aims to determine the domicile distribution, find out the high-risk areas, and determine the risk of drug-resistant tuberculosis patients based on patient location in 15 districts of Makassar City from Tuberculosis register data of South Sulawesi Provincial Health Office in December 2017 – April 2019 period. Gen Xpert rapid or drug sensitivity examinations were used to define drug-resistant tuberculosis. The domicile location of patients was geocoded by maps in Google Earth and aggregated per area by using Kernel Density analysis using ArcView GIS 10.3 software. We found that drug-resistant tuberculosis cases tended to be clustered in the western part of Makassar City, an area with a fairly high population density. There were areas with the highest concentration of predicted cases as a high risk of transmission of drug-resistant TB, around the Bontoala District, Makassar District, and Mamajang District. Healthcare facilities located in hot spots area need to be equipped with molecular rapid test facilities and conduct drug sensitivity tests for all suspected tuberculosis patients. Further research needs to be carried out to determine the distribution of tuberculosis patients who are sensitive and resistant to drugs.