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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences
Ady Sumaryanto
Chemistry Department, University of Brawijaya
Agriculture, Biological Sciences & Forestry Environmental Science

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The Curative Activity of Isolated Fraction from Spathodea campanulata Beauv Stem Bark on Rats Exposed to Benzopyrene Masruri Masruri; Mohamad Lutfillah; Ady Sumaryanto; Rurini Retnowati; Aulanni'am Aulanni'am
Journal of Tropical Life Science Vol. 4 No. 3 (2014)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.04.03.01

Abstract

This paper reports a screening results of the secondary metabolites composed in Spathodea campanulata Beauv stem bark, evaluate inhibiting activity of malondialdehyde (MDA) on rats cancer model exposed with benzopyrene, and the histology of its lung. The secondary metabolite of the stem bark fraction consisted of alkaloids, flavonoids-phenolic, terpenoid and steroid compounds. The isolated fraction contained of these metabolites significantly indicate bioactivity by reducting of malondialdehyde (MDA) level, and also histology appearance of the lung tissue prepared from the benzopyrene-exposed rat indicated a curative activity.
Co-Authors Aulanni'am Aulanni'am Masruri Masruri Mohamad Lutfillah Rurini Retnowati