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All Journal journal of internal medicine The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Dewa Gde Agung Budiyasa
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Medicine & Pharmacology

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PENATALAKSANAAN KETOASIDOSIS DIABETIK (KAD) Gotera, Wira; Agung Budiyasa, Dewa Gde
journal of internal medicine Vol. 11, No. 2 Mei 2010
Publisher : journal of internal medicine

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Abstract

Diabetic Ketoasidosis (DKA) is metabolic disturbance disorder that be signed by trias hyperglycemia, acidosis, andketosis, which one of very serious acute metabolic complication of diabetes mellitus. In Indonesia the incidence was not sohigh compare than the western countries, but the mortality is still high. In young age the mortality can be prevented by earlydiagnosis, rational and prompt treatment according to it!s pathophysiology. Succesfull of DKA treatment needs correction ofdehidration, hyperglycemia, acidosis, and electrolyte disturbance, identiÞ cation of comorbid precipitation factor, and the mostimportant one was continue monitoring. The treatment were adequate of ß uid therapy, sufÞ cient insulin theraphy, therapy ofpotassium, bicarbonate, phosphat, magnesium, hyperchloremic condition, and antibiotic administration according to indication.The important one was also awarness for therapy complications so that the therapy not to make worsening condition of thepatients.
HUBUNGAN ANTARA DERAJAT BERAT INFEKSI VIRUS DENGUE DAN KADAR NATRIUM SERUM Agung Budiyasa, Dewa Gde; Parwati Merati, K Tuti
journal of internal medicine Vol. 12, No. 1 Januari 2011
Publisher : journal of internal medicine

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Abstract

Dengue Viral (DV) infection has been a big problem on the world (WHO, 2005). One of the factors that can inß uencesuccesfull of the DV infection treatment was correction for hyponatremia as one of the factors caused dengue encephalopathy.Hyponatremia cause by plasma leakage, the more severe plasma leakage the more severe hyponatremia. The aim of this study toknow association between degree of severity of DV infection and natrium serum concentration, correlation between two signsof plasma leakage (albumin concentration and hematocrit) with serum natrium concentration. Analytic cross sectional designbe applied for DV infection patients who admitted at Internal Medicine Department of Sanglah General Hospital on November! December 2010. Pearson correlation test showed signiÞ cant correlation between albumin and serum natrium (p = 0.018, r =0.254), no signiÞ cant correlation between hematocrit and natrium serum (p = 0.861, r = 0.019). Linear regression showed pvalue for albumin 0.495 and degree of severity of DV infection 0.000, so variable that can predict natrium serum concentrationwas degree of severity of DV infection, stated with formula y = 134,515 - 2,664x. The conclusion we found there was negativeassociation between degree of severity of DV infection and natrium serum concentration which signiÞ cant between DF and DHF.But among degree of DHF there were just tendention that the more severe degree of severity of DHF the lower serum natriumconcentration. There was signiÞ cant correlation between albumin and natrium serum concentration, but albumin can"t predictnatrium serum concentration. No signiÞ cant correlation between natrium serum concentration and hematocrit. We suggest tomeasure natrium serum concentration to antisipate worsening of DV infection, and better be performed for serial examination.
HUBUNGAN ADIPONEKTIN DENGAN GAGAL JANTUNG KONGESTIF Agung Budiyasa, Dewa Gde; Santoso, Anwar
journal of internal medicine Vol. 9, No. 3 September 2008
Publisher : journal of internal medicine

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Abstract

Adipose tissue synthesis several protein involved in the regulation of insulin action and lipid metabolism. Among theprotein adipocytokines, adiponectin is the most abundant and exerts profound anti-diabetic, anti-atherogenic, and anti-inflammatoryroles. Adiponectin may contribute to the regulation of vascular hemostasis by its ability to affect several signaling pathwaysin the vessel wall and modulate excess inflammatory responses. In the heart, adiponectin serve as a regulator of cardiacinjury through modulation of pro-survival reaction, cardiac energy metabolism, and inhibition of hypertropic remodelling. Manyeffect of adiponectin in the cardiovascular system correlate with the activation of both AMPK and Cox-2.Adiponectin levels may influence the development of CHF, but the epidemiological data are somewhat complex. This isdue in part to the fact that while higher body mass indices are a risk factor for heart failure, obesity is a predictor of improveprognosis in patients with establish CHF because wasting is strongly associated with the increased risk of death in the final stageof this disease. In this regard, high adiponectin levels are a predictor of mortality in patients with heart failure. Presumably, thisparadoxical relationship exist because high body mass, hence low protein, favors survival in endstage heart failure. Therefore,further studies should examine adiponectin levels in patients with stable heart failure
Correlation between Serum Albumin Level and Degree of Esophageal Varices in Patients with Liver Cirrhosis Dewa Gde Agung Budiyasa; Yuna Ariawan; I Ketut Mariadi; I Dewa Nyoman Wibawa; Nyoman Purwadi; I Gusti Agung Suryadarma
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 12, NUMBER 1, April 2011
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/121201123-27

Abstract

Background: It has not been clear about how often the patient should have esophago- gastroduodenoscopy (EGD) screening for esophageal varices (EV) detection and there is only some data that demonstrates the correlation between the degree of EV and non-endoscopic variables. It is assumed that the presence of EV detected though examination of serum albumin level may trim down the unnecessary endoscopy. This study was aimed to recognize the correlation between albumin level and the degree of EV in patients with liver cirrhosis. Method: A retrospective analysis was performed for 61 patients with liver cirrhosis who had EGD at Sanglah hospital between January and December 2008. Spearman test was used to analyze the correlation between albumin level and the degree of EV. Results: There were 61 patients of 45 (73.8%) male and 16 (26.2%) female. The range age of patients was 13–77 years (average 49.98 ± 1.62 years). Serum albumin level ranged between 1.10-3.60 mg/dL, the average value was 2.21 ± 0.451 mg/dL. We also found 8 (13.1%) patients without EV, 14 (23.0%) patients with EV grade I, 21 (34.4%) patients with grade II and 18 (29.5%) patients with grade III. A negative correlation was found between serum albumin level and the degree of EV (r = - 0.587; p = 0.000, p 0.01). Conclusion: Serum albumin level can predict the presence and the degree of EV in patients with liver cirrhosis.   Keywords: albumin, degree of EV, liver cirrhosis
Co-Authors Anwar Santoso I Dewa Nyoman Wibawa I Gusti Agung Suryadarma I Ketut Mariadi Ketut Tuti Parwati Merati Nyoman Purwadi Wira Gotera Yuna Ariawan