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Febriana, Gabriella Gita
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Medicine & Pharmacology Public Health

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Journal : Indonesian Journal of Life Sciences

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Drug-Resistant Pulmonary Tuberculosis Putri, Olivia; Salim, Megan Angelita; Gunawan, Aileen; Devin, Devin; Amaris, Ezrela; Alexander, David; Kevin, Gregorius; Febriana, Gabriella Gita
Indonesian Journal of Life Sciences 2023: IJLS Vol 05 No .01
Publisher : Indonesia International Institute for Life Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54250/ijls.v5i01.172

Abstract

Tuberculosis (TB) caused by the pathogenic bacteria Mycobacterium tuberculosis (MTb) still remains a highly prevalent disease, particularly in low and middle-income countries. Due to the bacteria’s atypical cell wall structure, ability to form granuloma, and capacity to switch between replicating and non-replicating states in the host lung parenchyma, the fundamental treatment of patients diagnosed with TB involves a 6-month long daily drug administration. With Indonesia ranking among the nations with the highest TB burden worldwide, there has been an alarming increase of drug-resistant MTb (DR-MTb) strains all over the country in recent years. However, there are currently limited studies available that highlight MTb resistance profiles across different regions within Indonesia. The major risk factors contributing to the emergence and spread of TB in Indonesia include health conditions, environmental conditions, and socioeconomic status. Furthermore, natural compounds and drug repurposing can be employed to combat the further spread of DR-MTb strains across the country, especially in rural regions.
Effects of SARS CoV-2 mRNA Vaccines on Graves' Disease Febriana, Gabriella Gita
Indonesian Journal of Life Sciences 2023: IJLS Vol 05 No .02
Publisher : Indonesia International Institute for Life Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54250/ijls.v5i02.180

Abstract

The development of SARS CoV-2 mRNA vaccines has been claimed as a breakthrough in the medical research field. Moreover, these vaccines have been proven to reduce SARS CoV-2 transmission. However, the administration of these vaccines also found to interfere with thyroid functions in some individuals, which include newly onset Graves’ disease in immunocompromised people and worsening condition in Graves’ disease patients. This article reviews cases on Graves’ disease following the administration of first and second dose of SARS CoV-2 mRNA vaccines between the year 2021 and 2022. Furthermore, the possible mechanisms of Graves’ disease development following mRNA vaccines administration are being discussed in this review article.
Co-Authors Alexander, David Amaris, Ezrela de Vries, Victor Christoff Devin, Devin Gunawan, Aileen Kevin, Gregorius Putri, Olivia Salim, Megan Angelita