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All Journal Cermin Dunia Kedokteran
S.T. Lim, Zack
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Health Professions Medicine & Pharmacology Public Health

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A Review of Gene Editing/Therapy and CRISPR Technology S. Ong, Khing; S.T. Lim, Zack; Setiawan, Boenjamin
Cermin Dunia Kedokteran Vol 46, No 6 (2019): Diabetes Mellitus
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (221.457 KB) | DOI: 10.55175/cdk.v46i6.470

Abstract

This review will discuss the gene editing or manipulation in general, including various methods and tools currently available, including CRISPR. Some encouraging results of clinical applications of gene-therapy will also be discussed. With its diverse and far reaching effect on biomedical field, we will also discuss CRISPR technology beyond its gene-editing functions. We also review the cost for performing a gene-therapy.Ulasan ini membahas penyuntingan atau manipulasi gen umumnya, berbagai cara dan alat yang kini tersedia, termasuk teknologi CRISPR. Akan disajikan pula hasil-hasil percobaan klinik yang memberi harapan. Mengingat pengaruhnya yang luas di bidang biomedis , akan dibahas pula pemanfaatannya di bidang lain. Akhirnya, akan dibicarakan juga hal-hal terkait biaya pengeditan terapi gen yang sangat tinggi, dengan harapan bisa ditekan di masa yang akan datang dengan teknologi yang lebih canggih.
Co-Authors Boenjamin Setiawan S. Ong, Khing