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Efektivitas Ekstrak Etanol Biji Pinang Terhadap Densitas GLUT4 pada Sel-Sel Otot Rangka Mencit yang Terinduksi Hiperglikemia MULIA SAFRIDA SARI; AHMAD RIDWAN
Jurnal Sumberdaya Hayati Vol. 2 No. 2 (2016)
Publisher : Departemen Biologi, Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jsdh.2.2.52-58

Abstract

Betel nut (Areca catechu) was proven to have antihyperglycemic activity through increased PI3K pathway in the GLUT4 translocation in cells. However, research on the ethanol extract of betel nut in Indonesia is still limited. The main problem in this study was whether the ethanol extract of betel nut could improve glucose tolerance in a two-hour postprandial period and whether the ethanol extract of betel nut could induce GLUT4 translocation in skeletal muscle cells of mice induced hyperglycemia. Glucose tolerance test results showed that treatment of the ethanol extract of betel nut for 24 days with all doses tested: P50,100,150,200 and 250 mg/kg body weight could improve glucose tolerance in a two-hour postprandial period. The protein electrophoresis of that fasting and one hour postprandial state treatments resulted an increase in GLUT4/βActin density ratio of P250 group compared to negative and positive controls. In this case, GLUT4/βActin density ratio of P100,P200 and P250 were higher than that GLUT4/βActin density ratio of P50 and P150. Increased in GLUT4/βActin density ratio showed enhancement of the GLUT4 in skeletal muscle cells in fasting and one hour postprandial state after treated with ethanol extract of betel nut. 
MODEL PERTANIAN ORGANIK BERBASIS TANAMAN CEPAT PANEN DAN TOGA UNTUK KEMANDIRIAN PANGAN DAN PENGENDALIAN PENYAKIT PASCA BANJIR DI DESA PAYA UDANG KECAMATAN SERUWAY KABUPATEN ACEH TAMIANG Mulia Safrida Sari; Muna Aulia Tiba; Muhammad Irfan; Selvia Williadani; Attariq Syah; Kasmiriati Br Harahap; Bustanul Akmal Putra
Jurnal Masyarakat Berdikari dan Berkarya (Mardika) Vol 1 No 1 (2023): Jurnal Masyarakat Berdikari dan Berkarya (MARDIKA)
Publisher : Fakultas Teknik, Universitas Samudra

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55377/mardika.v1i1.8164

Abstract

Disease and food insufficiency are serious problems faced by community at the post-flood in Paya Udang Village, Seruway District, Aceh Tamiang Regency. To overcome these problems, a community service program was carried out in the form of making an organic farming model based on quick-harvest crops and toga plants. This program aims to increase local food production, food independence, and post-flood disease control through the application of sustainable organic farming practices. Fast-harvest crops such as spinach, kale, and cassava were chosen because they can provide quick results and meet the food needs of the community. Toga plants such as lemongrass were also introduced as a natural mosquito repellent and an effort to prevent mosquito-borne diseases. The program involves the active participation of the community, farmer groups, and the KKN team in the process of land clearing, soil preparation, planting, plant maintenance, and organic pest control. Through training, counseling, and mentoring, the community's knowledge and skills in organic farming are improved. The results of this program include increased local food production, diversified food consumption, increased food self-sufficiency, and post-flood disease risk control. In addition, the program also provides recommendations for policy development that supports organic farming and food sustainability at the local and national levels.