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All Journal Journal of Dentistry Indonesia Makara Journal of Health Research
Lim, Tong Wah
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Dentistry

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The Relationship of Facial Measurements with the Mesiodistal Width of the Maxillary Anterior Teeth Aziz, Nur Ilyana Aifa; Che Mohd, Nadia; Baharuddin, Izyan Hazwani; Rajali, Aiemeeza; Lim, Tong Wah; Tan, Su Keng; Ahmad, Rohana
Journal of Dentistry Indonesia
Publisher : UI Scholars Hub

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The relationship between facial measurements and the size of the maxillary anterior teeth in the Malaysian population is still a point of contention. Objective: The purpose of this study was to establish a relationship between facial measurements and the mesiodistal width of the maxillary anterior teeth (MDW), which could be used to guide the selection of anterior teeth for complete denture construction. Methods: The facial and dental measurements were obtained directly from 170 Malay adults aged between 19 to 35 who had morphologically normal permanent maxillary anterior teeth from canine to canine. The facial dimensions measured were interpupillary distance (IPD), intercanthal distance (ICD) and interalar distance (IAD). The facial dimensions were measured using a digital vernier calliper while the mesiodistal width of the maxillary anterior teeth was measured with a flexible ruler. The three facial dimensions were correlated with MDW for both genders. Results:The IPD and IAD were significantly (p>0.001) larger in males (IPD: 68.30±4.24mm; IAD: 39.60±2.54mm) than in females (IPD: 65.93±3.91mm; IAD: 36.96±2.29). There was no significant correlation between any of the facial dimensions and MDW in males or females. Conclusion: For the studied population, the interpupillary, intercanthal, and interalar distances may not be used as reliable guides when determining the size of maxillary anterior teeth in complete denture construction.
Comparative Analysis of Proteomics Biomarkers Associated with Residual Ridge Resorption Induced by Denture Wear Ahmad, Rohana; Mohamad Napi, Ainin Sofia; Lim, Tong Wah; Tan, Su Keng; Karsani, Saiful Anuar; Mazlan, Musalmah; Teh, Lay Kek; Morgano, Steven M; Baba, Nadim Z
Makara Journal of Health Research Vol. 25, No. 2
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Background: The biochemical bone turnover markers for residual ridge resorption (RRR) are unclear. Therefore, the present study aimed to determine the biochemical bone turnover markers associated with RRR by comparing proteomics between the compressed mucosa of denture wearers and the non-compressed mucosa of non-denture wearers. Methods: The mucosal specimens of 11 complete-denture wearers were obtained from the alveolar ridge during surgical implant exposure for implant-retained overdentures. All denture wearers had been edentulous and worn dentures for at least 5 years. The tissues of 11 non-denture wearers were taken from the ridge during minor preprosthetic surgery. The mucosal proteins were extracted, purified, precipitated, and subsequently separated by two-dimensional gel electrophoresis for comparative proteomics. Differentially expressed proteins between the groups were analyzed by ANOVA using Progenesis SameSpots software. Results: Comparative proteomics analysis showed significant upregulation of 78 kDa glucose-regulated protein (GRP78; +2.2 fold, p = 0.015) and lumican (+1.8 fold, p = 0.005), as well as significant downregulation of heat shock protein 27 (HSP27; −1.9 fold, p = 0.029) in the denture group. Conclusions: Differential expression of the biochemical bone turnover markers of GRP78, lumican, and HSP27 may occur as a result of denture pressure on the mucosa. These markers may play important roles in RRR.
Co-Authors Ahmad, Rohana Aziz, Nur Ilyana Aifa Baba, Nadim Z Baharuddin, Izyan Hazwani Che Mohd, Nadia Karsani, Saiful Anuar Mazlan, Musalmah Mohamad Napi, Ainin Sofia Morgano, Steven M Rajali, Aiemeeza Tan, Su Keng Teh, Lay Kek