Article Per Year (5 Year)
p-Index From 2019 - 2024
0.408
P-Index
This Author published in this journals
All Journal Indonesian Journal of Tropical and Infectious Disease Bali Dermatology and Venereology Journal
Anis Irawan Anwar
Department Of Dermatology, Hasanudin Medical Faculty, Makassar
Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Health Professions Medicine & Pharmacology Public Health

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
COMPARATIVE STUDY ON THE INTENSITY OF Mycobacterium leprae EXPOSURE BETWEEN HOUSEHOLD AND NONHOUSEHOLD CONTACT OF LEPROSY Arsyad, Yuniarti; Jifanti, Friska; Amiruddin, Muhammad Dali; Anwar, Anis Irawan; Adriaty, Dinar; Wahyuni, Ratna; Iswahyudi, Iswahyudi; Agusni, Indropo
Indonesian Journal of Tropical and Infectious Disease Vol 3, No 1 (2012)
Publisher : Institute of Topical Disease

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1081.524 KB)

Abstract

Leprosy stills a public health problem in West Sulawesi which has a Case Detection Rate (CDR) around 43.69/100.000 population. Household contacts of leprosy are a high risk group to be infected, due to droplet infection mode of transmission of the disease. A nose swab examination and serological study was conducted to detect exposure of M. leprae of people who live in leprosy endemic area. Detection of M. leprae in the nasal cavity will represent the exposure rate from outside and the measurement of specific antibody is represented the result of exposure to the immune system. Two group of inhabitants (30 household contacts of leprosy and 30 nonhousehold contacts) were involved in the study. They live in Banggae district, a leprosy endemic area of Majene Regency, West Sulawesi. Sixty nose swab samples and sixty capillary blood samples from the same invidividuals of the two groups were collected and sent to Leprosy laboratory of the Institute of Tropical Disease, Airlangga University Surabaya. A Polymerase Chain Reaction (PCR) was performed to the nose swab samples for detection of M. leprae. The blood samples were examined serologically to measure the level of anti PGL-1 antibody. PCR examination of nose swab samples showed 1/30 positive result in the household contact group and also 1/30 positive result in non-household contact of leprosy (statistically no significant difference, p > 0.05). Serological study showed higher sero-positive result in the household contact group (15/30 or 50%) compared to non-household contact (11/30 or 36%), but statistical calculation revealed no significant difference between the two groups (p > 0.05) on sero-positive results of leprosy. It is concluded that household and non-household contact in leprosy have the same risk to be affected by the disease. The term of household and non-household contact need to be redefined. The possible role of exposure from the environment was also discussed, especially from non-human resource of M. leprae.
The effectiveness of galactomyces ferment filtrate, dexpanthenol and Centella asiatica combination serum in the treatment of post-acne hyperpigmentation Dewi, We Sagara; Kurniadi, Ivan; Anwar, Anis Irawan
Bali Dermatology and Venereology Journal Vol 3, No 2 (2020)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v3i2.25

Abstract

Background: Acne vulgaris is a chronic inflammation of the pilosebaceous gland that may result in both non-inflammatory and inflammatory lesions. Post-acne hyperpigmentation (PAH) is caused by a hypermelanotic reaction to skin inflammation. It can occur secondary to the inflammation process and depending on the severity, may persist for a prolonged period.Objective To determine the effectiveness of galactomyces ferment filtrate (GFF), dexpanthenol, and Centella asiatica combination serum in the treatment of PAHMethods: This was a placebo-controlled randomized clinical trial. There are 68 subjects  that were divided into two groups: the experimental group received combination serum while the control group received placebo for 8 weeks. Three drops of serum were applied to the area with PAH twice daily in the morning and at night. The melanin, erythema, roughness, and L*, a*, and b* scores were assessed objectively using mexameter, chromameter and skin analyzer for every two weeks. Pearson’s correlation test and independent T-test were used to assess the trend of the parameters and compare the results of both groups.Results: The results of statistical calculations using Pearson correlation test showed the treatment group showed a significant decreasing trend of the melanin and spots score. Both groups showed significant decreasing trend in erythema, L* score and roughness. However, no significant difference was found between both groups in all parameters.Conclusion: The combination serum may decrease the melanin and spot scores suggesting that it affects the melanocyte activity. It has shown a good efficacy in treating PAH.
COMPARATIVE STUDY ON THE INTENSITY OF Mycobacterium leprae EXPOSURE BETWEEN HOUSEHOLD AND NONHOUSEHOLD CONTACT OF LEPROSY Yuniarti Arsyad; Friska Jifanti; Muhammad Dali Amiruddin; Anis Irawan Anwar; Dinar Adriaty; Ratna Wahyuni; Iswahyudi Iswahyudi; Indropo Agusni
Indonesian Journal of Tropical and Infectious Disease Vol. 3 No. 1 (2012)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1081.524 KB) | DOI: 10.20473/ijtid.v3i1.192

Abstract

Leprosy stills a public health problem in West Sulawesi which has a Case Detection Rate (CDR) around 43.69/100.000 population. Household contacts of leprosy are a high risk group to be infected, due to droplet infection mode of transmission of the disease. A nose swab examination and serological study was conducted to detect exposure of M. leprae of people who live in leprosy endemic area. Detection of M. leprae in the nasal cavity will represent the exposure rate from outside and the measurement of specific antibody is represented the result of exposure to the immune system. Two group of inhabitants (30 household contacts of leprosy and 30 nonhousehold contacts) were involved in the study. They live in Banggae district, a leprosy endemic area of Majene Regency, West Sulawesi. Sixty nose swab samples and sixty capillary blood samples from the same invidividuals of the two groups were collected and sent to Leprosy laboratory of the Institute of Tropical Disease, Airlangga University Surabaya. A Polymerase Chain Reaction (PCR) was performed to the nose swab samples for detection of M. leprae. The blood samples were examined serologically to measure the level of anti PGL-1 antibody. PCR examination of nose swab samples showed 1/30 positive result in the household contact group and also 1/30 positive result in non-household contact of leprosy (statistically no significant difference, p > 0.05). Serological study showed higher sero-positive result in the household contact group (15/30 or 50%) compared to non-household contact (11/30 or 36%), but statistical calculation revealed no significant difference between the two groups (p > 0.05) on sero-positive results of leprosy. It is concluded that household and non-household contact in leprosy have the same risk to be affected by the disease. The term of household and non-household contact need to be redefined. The possible role of exposure from the environment was also discussed, especially from non-human resource of M. leprae.
The effectiveness of galactomyces ferment filtrate, dexpanthenol and Centella asiatica combination serum in the treatment of post-acne hyperpigmentation We Sagara Dewi; Ivan Kurniadi; Anis Irawan Anwar
Bali Dermatology and Venereology Journal Vol. 3 No. 2 (2020)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v3i2.25

Abstract

Background: Acne vulgaris is a chronic inflammation of the pilosebaceous gland that may result in both non-inflammatory and inflammatory lesions. Post-acne hyperpigmentation (PAH) is caused by a hypermelanotic reaction to skin inflammation. It can occur secondary to the inflammation process and depending on the severity, may persist for a prolonged period.Objective To determine the effectiveness of galactomyces ferment filtrate (GFF), dexpanthenol, and Centella asiatica combination serum in the treatment of PAHMethods: This was a placebo-controlled randomized clinical trial. There are 68 subjects  that were divided into two groups: the experimental group received combination serum while the control group received placebo for 8 weeks. Three drops of serum were applied to the area with PAH twice daily in the morning and at night. The melanin, erythema, roughness, and L*, a*, and b* scores were assessed objectively using mexameter, chromameter and skin analyzer for every two weeks. Pearson’s correlation test and independent T-test were used to assess the trend of the parameters and compare the results of both groups.Results: The results of statistical calculations using Pearson correlation test showed the treatment group showed a significant decreasing trend of the melanin and spots score. Both groups showed significant decreasing trend in erythema, L* score and roughness. However, no significant difference was found between both groups in all parameters.Conclusion: The combination serum may decrease the melanin and spot scores suggesting that it affects the melanocyte activity. It has shown a good efficacy in treating PAH.
Co-Authors Dewi, We Sagara Dinar Adriaty DINAR ADRIATY Friska Jifanti Friska Jifanti Indropo Agusni INDROPO AGUSNI Iswahyudi Iswahyudi ISWAHYUDI ISWAHYUDI Ivan Kurniadi Kurniadi, Ivan Muhammad Dali Amiruddin Muhammad Dali Amiruddin Ratna Wahyuni RATNA WAHYUNI We Sagara Dewi Yuniarti Arsyad Yuniarti Arsyad, Yuniarti