Article Per Year (5 Year)
p-Index From 2019 - 2024
0
P-Index
This Author published in this journals
All Journal Nexus Biomedika
Monica Citraningtyas Astarani
Faculty of Medicine, Sebelas Maret University
Biochemistry, Genetics & Molecular Biology

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Pengaruh Ekstrak Etanol Daun Alpukat (Persea americana Mill.) terhadap Mortalitas Cacing Ascaris suum, Goeze in Vitro Astarani, Monica Citraningtyas; Sukilarso, Bambang; Haryati, Sri
Nexus Biomedika Vol 2, No 2 (2013): Nexus Biomedika
Publisher : Nexus Biomedika

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (13.862 KB)

Abstract

Background  : Avocado leaves which have been known from phytochemical contain flavonoid, tannin katekat, quinone, saponin, and steroid/triterpenoid. Saponin and tannin are active substances which have anthelmintic effect. This research was to know the effect of avocado (Persea americana, Mill.) leaves ethanol extract toward the mortality of Ascaris suum, Goeze in vitro. Methods : This study was experimental laboratory research with the post test only controlled group design. The subjects were 150 adult Ascaris suum, Goeze, arranged into 6 groups. NaCl 0.9 % solution was treated to negative control group, while 5 mg/ml pirantel pamoat solution was treated to positive control. The others group were treated with 60%, 70%, 80%, 90% w/v of Avocado (Persea Americana, Mill.) leaves ethanol extract. Observation was done in every hour until all worm died. The data were analyzed by linear regression and probit analysis. Results   : Probit analysis showed that LC50 and LT50 of Avocado leaves extract were 56.42% dan 665.15 minutes. Linear regression analysis showed there was  significant (p < 0.05) effect between the time of death and variation of extract concentration. Conclusion : Avocado (Persea americana Mill.) leaves ethanol extract had significant effect toward the mortality of Ascaris suum, Goeze in vitro. Keywords : avocado leaves ethanol extract, Ascaris suum, LC50
Co-Authors Bambang Sukilarso Sri Haryati