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All Journal Jurnal Pendidikan Kimia Indonesia Pharmaciana: Jurnal Kefarmasian Journal of Science Learning Biosaintifika: Journal of Biology & Biology Education
Nurfina Aznam
Fakultas Farmasi UAD
Agriculture, Biological Sciences & Forestry Chemistry Education Medicine & Pharmacology

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UJI EFEK ANTIHIPERGLIKEMIK EKSTRAK ETANOL DAUN KACAPIRING (Gardenia augusta, Merr) PADA TIKUS PUTIH JANTAN GALUR WISTAR Baroroh, Faridah; Aznam, Nurfina; Susanti, Hari
PHARMACIANA Vol 1, No 1: Mei 2011
Publisher : PHARMACIANA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (82.03 KB)

Abstract

Daun kacapiring (Gardenia augusta, Merr) sering digunakan secara tradisional untuk pengobatan diabetes mellitus. Penelitian ini dilakukan untuk mengetahui apakah ekstrak etanol daun kacapiring dapat menurunkan kadar glukosa darah pada tikus putih jantan galur Wistar dan seberapa besar efek antihiperglikemiknya jika dibandingkan dengan obat antidiabetes glibenklamid. Penelitian ini menggunakan metode uji toleransi glukosa oral dengan pembebanan glukosa dosis 4,5 g/kgBB. Hewan uji yang digunakan tikus putih jantan galur Wistar umur 2-3 bulan, berat badan 180-250 gram, sebanyak 24 ekor yang dibagi menjadi 4 kelompok masing-masing kelompok terdiri dari 6 ekor tikus. Kelompok I sebagai kelompok kontrol negatif diberi CMC-Na 1%, kelompok II sebagai kelompok kontrol positif diberi glibenklamid dosis 1,35 mg/kgBB, kelompok III dan kelompok IV diberi ekstrak etanol daun kacapiring masing-masing dosis 500 mg/kgBB dan 250 mg/kgBB. Glibenklamid dan ekstrak diberikan secara peroral 60 menit sebelum pemberian glukosa. Pengambilan darah melalui sinus orbitalis secara keseluruhan dilakukan pada menit ke-(-90), (-60), 0, 30, 60, 120, 180, 240, dan 300. Kadar glukosa darah diukur dengan metode enzimatik dengan pereaksi GOD PAP (Glucose Oxidase Phenol 4-Aminoantipirin) yang menghasilkan larutan merah dan absorbansi dibaca dengan spektrofotometer UV-Vis pada panjang gelombang 500 nm. Hasil penelitian menunjukkan bahwa ekstrak etanol daun kacapiring dosis 500 mg/kgBB dan 250 mg/kgBB dapat berefek menurunkan kadar glukosa darah. Ekstrak etanol daun kacapiring dosis 500 mg/kgBB dan 250 mg/kg dapat menurunkan kadar glukosa darah sebesar 58,97% dan 80,60% disbanding glibenklamid dosis 1,35 mg/kgBB yang dapat menurunkan kadar glukosa darah sebesar 73,93%.
Development of Natural Sciences Module with Reflective Learning Journal to Enhance Student’s Reporting-Interpretative Skills Zulfah, Hadaina; Aznam, Nurfina
Biosaintifika: Journal of Biology & Biology Education Vol 10, No 2 (2018): August 2018
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v10i2.14319

Abstract

One of the successful factors of the curriculum 2013 implementation is the availability of appropriate and relevant teaching materials. Teaching materials can be textbooks, interactive videos , virtual labs, maket and so on. Unfortunately, there are still found many materials that are less in accordance with the curriculum of 2013. Therefore it should be developed a more appropriate teaching materials, one of them is a natural sciences module with reflective learning journal. The development of natural sciences modulewas done with research that aims to develop and analyze the effectiveness of natural sciences modulewith reflective learning journals. This research was an R&D research using development research procedure according to Thiagarajanthat known as 4D (define, design, develop and dessiminate). The data collection was done by test and non-test technique. Instrument that used in non test technique are interview guides, product validation sheet, students’ response sheet to the readability of science nature modul with reflective learning journal., meanwhile the instrumen that used in test technique is essay question with reporting-interpretative skills’s indicators. The results showed that the leligibility of the natural sciences module with reflective learning journal was categorized as approriate and effective to improve student’s reporting-interpretative skills.
The Effect of The Science Web Module Integrated on Batik’s Local Potential Towards Students’ Critical Thinking and Problem Solving (Thinking Skill) Putri, Agnesi Sekarsari; Aznam, Nurfina
Journal of Science Learning Vol 2, No 3 (2019): Journal of Science Learning
Publisher : Universitas Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17509/jsl.v2i3.16843

Abstract

The 21st-century learning paradigm requires teachers to provide teaching materials that can develop students' thinking skills. This research aims to determine the effect of the web module science integrated local batik potential toward the thinking ability of seventh-grade students of junior high school. The research method used was quasi-experimental design with a posttest-only design. The instrument used is about thinking skill. The data analysis technique is a Kruskal Wallis test and Effect Size. The results of the research showed that there were differences in students' thinking skill between the experimental class and the control class, as indicated by the Kruskal Wallis test, gives significant results. Web science module integrated with local batik potential has a significant influence on students' thinking skill as indicated by Cohen's effect size score of 0.8. The results of this research can be used to provide insights to science teachers create innovative learning materials to make students more interested in learning science and practicing thinking skills of students.
MEDIA PADLET BERBANTUAN PHET SIMULATION PADA MATERI ATOM TERHADAP HASIL BELAJAR KOGNITIF DAN RESPON SISWA PADA MASA PANDEMI COVID-19 Afifah, ST; Nurhidayanti, Ani; Jumadi, Jumadi; Aznam, Nurfina
Jurnal Pendidikan Kimia Indonesia Vol 5, No 2 (2021)
Publisher : Universitas Pendidikan Ganesha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23887/jpk.v5i2.35612

Abstract

Masa pandemi Covid-19 pada saat ini sangat bergantung pada Kemajuan teknologi. Pembelajaran secara online menyebabkan suatu masalah kecemasan, ketidaksetaraan antara anak-anak karena akses, beresiko kecanduan internet, tidak memiliki disiplin belajar yang diperlukan dalam pendidikan individu Sehingga pada penelitian ini bertujuan untuk menganalisis hasil belajar dan respon siswa setelah pembelajaran menggunakan media padlet berbantuan phet simulation. Metode penelitian yang digunakan adalah quasi eksperimental desain dengan desain penelitian one group pretest and posttest. Subjek penelitian adalah siswa kelas IX. Teknik analysis data menggunakan uji paired sample t test . Hasil uji normalitas pretest dan posttest di peroleh nilai hasil pretest sebesar 0,053 dan hasil postest 0,056. Sehingga dapat disimpulkan bahwa data terdistribusi normal. Hasil uji hipotesis menunjukkan bahwa nilai siginifikansi 2 arah yaitu 0,000<0,05 yang menunjukkan bahwa H0 ditolak dan H1 diterima. Berdasarkan hasil penelitian diperoleh bahwa hasil belajar siswa antara tes pretest dan tes posttest setelah menggunkaan media padlet berbantuan phet simulation meningkat adapun respon siswa menyatakan baik terhadap penggunaaan media padlet berbantuan phet simulation ketika pembelajaran online. Jadi penggunaan media padlet berbantuan phet simulation cocok digunakan ketika proses pembelajaran online.
Co-Authors Afifah, ST Faridah Baroroh Hari Susanti Jumadi Jumadi Nurhidayanti, Ani Putri, Agnesi Sekarsari Zulfah, Hadaina