Dora Rahmanisah
STIFI Bhakti Pertiwi Palembang, Sumatera Selatan, Indonesia

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Uji Daya Hambat Minyak Atsiri Rimpang Kencur (Kaempferia galanga Linn) Terhadap Trichophyton mentagrophytes, Trichophyton rubrum Nilda Lely; Dora Rahmanisah
Jurnal Penelitian Sains Vol 19, No 2 (2017)
Publisher : Faculty of Mathtmatics and Natural Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (276.278 KB) | DOI: 10.56064/jps.v19i2.480

Abstract

The rhizome oil of galanga (Kaempferia galanga L.) was investigated for the antifungal activities against two dermatophytes (Trichophyton mentagrophytes and Tricophyton rubrum). The essential oil of rhi-zome of galanga obtained by steam distillation method was 0,465 (v/w). The antifungal testing was carried out by using agar diffusion method. 1%, 0,5%, 0,25%, and 0,1% were the used concentrations in this research. In a consentrations of 1% the rhizome oil of galanga had an average diameter of inhibition against Trichophyton mentagrophytes 11.8 ± 0.26 mm and a concentration of 0.5% have a diameter of inhibitory average of 7.93 ± 0.20 mm. Essential oils kencur (Kaempferia galanga L.) at a concentration of 1% had an average diameter of inhibition against Trichophyton rubrum 10.37 ± 0.25 mm ±, at a concentration of 0.5% have a diameter of in-hibition of 7.7 ± 0.2 mm.In 0,25% and 0,1% concentrations of essential oil of galanga showed no antifungal activity to T.mentagrophytes, T.rubrum.The chemical composition of the active essential oil was investigated by gas chromatography and mass spectrometry (GC-MS). The major chemical constituents were identified as ethyl cinnamate (65,98%) and ethyl p-metoxycinnamate (23,65%).