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All Journal Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi) Indonesian Journal of Cardiology
Dyana Sarvasti
Departemen Ilmu Penyakit Dalam, Fakultas Kedokteran Universitas Katolik Widya Mandala, Surabaya, RS Husada Utama, Surabaya
Computer Science & IT Engineering Health Professions Medicine & Pharmacology

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Journal : Indonesian Journal of Cardiology

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Perubahan metabolisme dan peran radikal bebas pada iskemia miokard Dyana Sarvasti
Jurnal Kardiologi Indonesia Vol. 36, No. 3 Juli - September 2015
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v36i3.480

Abstract

Myocardial ischemic results from severe impairment of coronary blood supply and produces a spectrum of clinical syndromes. It results in a characteristic pattern of metabolic and structural changes that leads to extremely complex situations, which have been extensively studied in recent years. A detailed understanding is now available of the complexity of the response of the myocardium to an ischemic insult. Reperfusion is the most effective way to treat the ischaemic myocardial. But, restoration of flow, however, might result in numerous other negative consequences, thus directly influencing the degree of recovery. Much evidence shows that during the period of myocardial ischemia and reperfusion can occur various changes both in terms of metabolic, electrical, histology, structural, and physiological. Pathological changes in the form of metabolic changes and the role of free radicals on the condition of ischemia and reperfusion injury will be discussed. There are several potential manifestations and outcomes associated with myocardial ischemia and reperfusion.
Co-Authors Adi Nugroho Adri Gabriel Sooai Agustinus Bimo Gumelar Paul L Tahalele