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All Journal International Journal of Integrated Health Sciences Althea Medical Journal Padjadjaran Journal of Dentistry
Indra Wijaya
Universitas Padjadjaran
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Malnutrition in Non-Hodgkin Lymphoma Patients at Dr. Hasan Sadikin General Hospital Bandung Azizah Puspitasari Ardinal; Siska Wiramihardja; Indra Wijaya
Althea Medical Journal Vol 6, No 1 (2019)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (56.609 KB) | DOI: 10.15850/amj.v6n1.1521

Abstract

Background: Non-hodgkin lymphoma (NHL) has the highest prevalence among hematologic malignancies. The prognosis and response to therapy in NHL patients may worsen in the presence of malnutrition. The aim of the study was to describe the malnutrition status in NHL patients. Methods: This was a cross-sectional descriptive study. Nutritional status was assessed using Subjective Global Assessment (SGA) obtained from the medical records of all NHL patients at Dr. Hasan Sadikin General Hospital registered in 2017.Results: In total, there were 78 medical records of NHL patients that fulfilled the inclusion criteria. All NHL patients had experienced malnutrition, categorized as mild-moderate malnutrition (70.5%) and severe malnutrition (29.5%). In NHL patients with mild-moderate malnutrition, 29% had 5–10% weight loss; 60% had suboptimal solid diet; 56.4% experienced anorexia; and 50.9% had subcutaneous fat loss. In NHL patients with severe malnutrition, 78.3% had more than 10% weight loss; 73.9% had suboptimal solid diet; 78.3% experienced anorexia; and 100% had subcutaneous fat loss.Conclusions: Based on subjective assessment, all NHL patients were malnourished and experienced change of food intake and loss of subcutaneous fat, therefore, a better nutritional support scheme are crucial for NHL patients.
Global Longitudinal Strain of Chronic Granulocytic Leukemia Patients treated with Imatinib and Nilotinib Indra Wijaya; Arief Sumarna; Eliza Nurazizah; Evan Susandi; Erwan Martanto
International Journal of Integrated Health Sciences Vol 9, No 2 (2021)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v9n2.2217

Abstract

Objective: To determine left ventricular function of patients with Chronic Granulocytic Leukemia in Chronic Phase (CGL-CP) who received imatinib and nilotinib by using Global Longitudinal Strain (GLS) examination.Methods: This was a descriptive study involving 46 CGL-CP patients who received imatinib and nilotinib therapy at the Hemato-Oncology Clinic of the Internal Medicine Departement of Dr. Hasan Sadikin General Hospital,, Bandung, Indonesia. Sampling was performed consecutively during the period of October to December 2019. Variables assessed in this study were age, gender, BMI, length of treatment, hemoglobin level, Left Ventricular Ejection Fraction (LVEF) value, and Global Longitudinal Strain (GLS). Primary data were tested for normality  using the Saphiro-Wilk test. Statistical analysis was performed using SPSS software version 25.0.Results: Thirty-nine patients (seventeen males and twenty-two females with a mean age of 42±11) who had been in therapy for about 8 to 179 months at the time of the study were included as subjects. On average, the GLS results for both treatment groups indicated a normal value based on the classification of the American Society of Echocardiography. The imatinib group gained a score of -22.4% (average range = -16.4% to (-28.1%)), while the nilotinib group gained a score of -21.6% (average range = -18.0% to (-25.9%)). Conclusion: This study described the left ventricular function based on results of GLS in CGL-CP patients receiving imatinib and nilotinib.
Characteristic patients with oral mucositis receiving 5-FU chemotherapy at Hasan Sadikin Hospital Bandung Syarifah Fatimah; Irna Sufiawati; Indra Wijaya
Padjadjaran Journal of Dentistry Vol 28, No 3 (2016): November 2016
Publisher : Faculty of Dentistry Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (188.735 KB) | DOI: 10.24198/pjd.vol28no3.13695

Abstract

Introduction: Oral mucositis is an inflammatory reaction of oral mucous membrane that often appears in cancer patients due to the chemotherapeutic agents, such as 5-fluorouracil (5-FU). The aim of this study was to describe the characteristic patients who receive 5-FU and had oral mucositis. Methods: This study was conducted on 41 patients with cancer receiving 5-FU chemotherapy at Dr Hasan Sadikin Hospital Bandung. The data was retrieved through interviews to find out patient’s characteristic; nutritional status examination by using body mass index measurement; and oral examination. Severity level was determined by using National Cancer Institute’s Common Toxicity Criteria scale, and the level of pain was measured by Numeric Pain Intensity Rating scale. Results: This research have shown 60,98% patient with cancer had received 5-FU chemotherapy treatment, and 44% with poor nutritional status (underweight). Oral mucositis was only found at non-keratinised mucous. The finding of this study was patients that receiving 5-FU chemotherapy treatment diagnosed with oral mucositis was on the 1st stadium (52%) and the 2nd stadium (44%) with the level of pain was on the mild level (48%) and moderate level (32%).Conclusion: Oral mucositis was found on patients with cancer that received 5-FU chemotherapy with a variety of characteristics, nutritional statuses, locations, levels of severity and pain.
Co-Authors Arief Sumarna Azizah Puspitasari Ardinal Eliza Nurazizah Erwan Martanto Evan Susandi Irna Sufiawati Siska Wiramihardja, Siska Syarifah Fatimah