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All Journal Jurnal SAGO Gizi dan Kesehatan Jurnal PADE: Pengabdian & Edukasi
Munira Munira
Jurusan Farmasi, Politeknik Kesehatan Kemenkes Aceh, Aceh
Dentistry Environmental Science Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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Uji antibakteri kombinasi ekstrak daun Biduri (Calotropis gigantea L.) dan daun Bandotan (ageratum conyzoides L.) Munira Munira; Fina Rodisa; Muhammad Nasir
Jurnal SAGO Gizi dan Kesehatan Vol 1, No 2 (2020): Januari - Juni
Publisher : Politeknik Kesehatan Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v1i2.410

Abstract

Background: Biduri leaves (Calotropis gigantea (L.) W.T. Aiton and Bandotan leaves (Ageratum conyzoides L.) are wild growing plants that are believed to be used as an antibacterial.Objectives: This research was conducted to determine the effect of combination ethanolic extract of Biduri and Bandotan leaves against Staphylococcus aureus and Staphylococcus epidermidis.Methods: This research is an experimental by using Completely Randomized Design (CRD) with 4 treatments which is P0 (aquadest), P1 (Biduri leaf extract), P2 (Bandotan leaf extract), and P3 (combination of Biduri and Bandotan leaf extract) with 5 replications. Microbiological test used was the diffusion method.Results: The results of Anova showed that combination of Biduri and Bandotan leaf extract very influential in the growth of Staphylococcus aureus dan Staphylococcus epidermidis. Duncan further test results showed that the largest average inhibition zone diameter in inhibiting Staphylococcus aureus was formed by P2 which is 14.14 mm, significantly different from P1 (9.46 mm) and P3 (11.20 mm), but P1 is not significantly different from P3. Toward Staphylococcus epidermidis, the largest average inhibition zone diameter also formed by P2 which is 17.06 mm that is also significantly different from P1 (10.14 mm) and P3 (12.66 mm), and P1 is not significantly different from P3.Conclusion: The combination of Biduri and Bandotan leaf extract very influential against Staphylococcus aureus and Staphylococcus epidermidis.
Pengaruh lama maserasi daun ketapang merah (Terminalia Catappa L.) terhadap daya hambat Staphylococcus aureus dan Escherichia coli Berwi Fazri Pamudi; Munira Munira; Rizky Amalia Saha; Muhammad Nasir
Jurnal SAGO Gizi dan Kesehatan Vol 2, No 2 (2021): Januari - Juni
Publisher : Politeknik Kesehatan Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v2i2.664

Abstract

Background: Bengal Almond leaves (Terminalia catappa L.) contain alkaloids, saponins, tannins, polyphenols, quinones, flavonoids and triterpenoids that can function as antibacterial.Objectives: This research was conducted to determine the effect of maceration time of red ketapang leaves (Terminalia catappa L.) on the growth of Staphylococcus aureus and Escherichia coli. Methods: This study was experimental using a completely randomized design (CRD) consisting of 6 treatments, that P0 (aquades), P1 (red ketapang leaf extract with 1 day maceration time), P2 (2 days maceration) P3 (3 days maceration) , P4 (4 days maceration) and P5 (5 days maceration) with 4 replications.Results: Anova test showed that macerated red ketapang leaf extract significantly affected the growth of Staphylococcus aureus and Escherichia coli (p= 0.000). Duncan's further test showed that the largest inhibition zone diameter in Staphylococcus aureus was formed by P2 (2 days maceration time) which was 18.62 mm and there was no significant difference between treatments. Meanwhile, the largest inhibition zone diameter against Escherichia coli was formed by P1 (1 day maceration time) which was 20.25 mm and there was a significant difference between treatments. Conclusion: Ketapang red leaf extract with different maceration times can inhibit the growth of Staphylococcus aureus and Escherichia coli.
Peningkatan pengetahuan dan keterampilan siswa siswi dalam pemanfaatan daun sirsak (Annona muricata L.) untuk pencegahan dan pengobatan berbagai penyakit di SMAN 1 Suka Makmur Aceh Besar Noni Zakiah; Munira Munira; Vonna Aulianshah
Jurnal PADE: Pengabdian & Edukasi Vol 3, No 2 (2021): Oktober
Publisher : Politeknik Kesehatan Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (249.848 KB) | DOI: 10.30867/pade.v1i2.704

Abstract

Penggunaan obat tradisonal yang semakin masif, dibutuhkan pengemasan dan penanganan cara pakai yang praktis bagi masyarakat. Daun sirsak adalah salah satu herbal yang  diketahui memiliki banyak khasiat farmakologis bagi kesehatan. Kapsul adalah salah satu alternatif bentuk pengemasan yang efisien bagi masyaakat karena selain memudahkan penggunaan, juga dapat menutupi rasa dan bau dari simplisia yang tidak enak. Kegiatan ini bertujuan untuk meningkatkan keterampilan siswa siswi dalam pemanfaatan daun sirsak (Annona Muricata L.) untuk pencegahan dan pengobatan berbagai penyakit. Kegiatan ini dilakukan dengan memberikan penyuluhan (metode ceramah) dan memberikan keterampilan cara mengemas serbuk simplisia daun sirsak ke dalam cangkang kapsul pada tanggal 28 November 2018 di SMAN 1 Suka Makmur Aceh Besar. Setelah diberikan penyuluhan ternyata terdapat peningkatan pengetahuan dan keterampilan pada para siswa dan siswi SMAN 1 Suka Makmur yang ditandai dengan meningkatnya rata-rata nilai post test dibandingkan rata-rata nilai pre test serta mahasiswa dapat mempraktikkan ulang demonstrasi pembuatan sediaan lapsul simplisia daun sirsak dengan lancar dan baik.
Uji Kadar Hambat Minimum (KHM) dan Kadar Bunuh Minimum (KBM) ekstrak daun kirinyuh (Chromolaena odorata) dari geothermal Ie Seum Aceh Besar terhadap Staphylococcus aureus Munira Munira; Muhammad Nasir
Jurnal SAGO Gizi dan Kesehatan Vol 4, No 2 (2023): Juni
Publisher : Politeknik Kesehatan Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v4i2.1107

Abstract

Background: Chromolaena odorata plant is a weed that grows abundantly in various places, including geothermal areas. Its leaves contain chemical compounds such as alkaloids, flavonoids, steroids, and tannins that can function as antibacterials.Objectives: The study aims to determine the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of ethanol extract of Chromolaena odorata leaves grown in the geothermal area of Ie Seum Aceh Besar against Staphylococcus aureus.Methods: The study was conducted at the Fundamental Microbiology Laboratory of Aceh Besar in June 2022. The MIC and MBC tests of ethanol extract of Chromolaena odorata leaves from the geothermal area of Ie Seum Aceh Besar were performed using the liquid dilution method. The concentrations of the extract used were 1%, 3%, 5%, 7%, and 10%. The MIC was determined based on the turbidity or clarity of the test solution, while the MBC was determined by streaking each concentration of the extract/test solution on agar media. Data analysis was performed descriptively in terms of the lowest concentration of the extract that could inhibit and kill Staphylococcus aureus.Results: The results showed that the ethanol extract of Chromolaena odorata leaves from the geothermal area of Ie Seum Aceh Besar had a MIC value of 5% and an MBC value of 7% in inhibiting the growth of Staphylococcus aureus.Conclusion: Based on the study, it can be concluded that the ethanol extract of Chromolaena odorata leaves from the geothermal area of Ie Seum Aceh Besar is able to inhibit the growth of Staphylococcus aureus from a concentration of 5% and able to kill Staphylococcus aureus from a concentration of 7%.
Co-Authors Berwi Fazri Pamudi Fina Rodisa Muhammad Nasir Noni Zakiah Rizky Amalia Saha Vonna Aulianshah