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All Journal Hemera Zoa PROSIDING SEMINAR NASIONAL CENDEKIAWAN
Miranti Candrarisna
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Biochemistry, Genetics & Molecular Biology Education

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WAAC-5 Flushing Aquaria with Hibiscus sabdariffa Extract on TNFα Expression in Fish Due To Mercury Intoxication Olan Rahayu Puji Astuti Nussa; Miranti Candrarisna; Laksmyn Kadir
Hemera Zoa Proceedings of the 20th FAVA & the 15th KIVNAS PDHI 2018
Publisher : Hemera Zoa

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (479.511 KB)

Abstract

The purpose of this study was to determine the expression of TNFα in the gills and liver tissue and the fish acute intoxication due to mercury, post-treatment using Rosella extract and flushing aquaria. It was an experimental study with a posttest only control group design consisting of 30 adult male fishes. There are 5 groups treatment including: P0 (healthy); P1 (mercury without Rosella extract and flushing; P2 (given mercury and Rosella extract of 5 ppm and flushing); P3 (given mercury and Rosella extract of 10 ppm and flushing); P4 (given mercury and Rosella extract of 20 ppm and flushing). Each group performed necropsy and examination immunohistochemical in the fish’s gills and liver on the 7th day after induction with mercury and on the 15th day of post-therapy using Rosella extract with flushing Aquaria. The results showed TNFα expression in the gills was different significantly and the the number was increasing compared to TNFα in the liver. The decrease of TNFα expression in the gills and liver were significantly different in the P4 group when compared to the other groups. In conclusion, Flushing aquaria and Rosella extract can reduce the TNFα expression in the fish’s gills and liver which experiencing mercury intoxication. Flushing Aquaria technology is a very appropriate method used for therapeutic in aquatic animals.
KOMPARASI EFEKTIVITAS UNGUENTUM KORAL KELIMUTU,KENCANA WUNGU DAN JAHE MERAH SEBAGAI TERAUPETIKA SCABIES PADA KAMBING PE Muhammad Farid Rizal; Miranti Candrarisna; Raden Roro Nurul Ramadhanti
PROSIDING SEMINAR NASIONAL CENDEKIAWAN Prosiding Seminar Nasional Cendekiawan 2017 Buku III
Publisher : Lembaga Penelitian Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/semnas.v0i0.2520

Abstract

Tujuan penelitian adalah untuk mengetahui komparasi efektivitas antaraunguentum coral kelimutu, infusum kencana wungu dan ekstrak jahe merah sebagaiteraupetika scabiosis pada kambing peranakan etawa. Jenis penelitian kualitatifeksperimental dengan rancangan acak lengkap.Metode penelitian: Pembuatan bahan darikoral kelimutu dan jahe merah dengan maserasi. Kencana wungu dibuat dengan metodeinfusum. Koral kelimutu, jahe merah, dan infusum kencana wungu ditimbang masingmasing sebanyak 50mg kemudian ditambahkan 50mg vaselin untuk membuat sedianunguentum. Kambing PE sebanyak 4 ekor pada bagian yang ditemukan investasiSarcoptes scabiei dibagian leher dan tengkuk. kambing yang tidak diberikan pengobatan(P0) diberi pengobatan unguentum koral kelimutu (P1), unguentum Jahe merah (P2) danunguentum infusum kencana wungu (P3) yang masing masing diberikan 2kali seharidalam 15 hari pemberian. Parameter yangdiamati adalah tingkat kesembuhan, inflamasi,penutupan luka/pertumbuhan bulu dan kematian parasit. Hasil penelitian menunjukan : P1menunjukan hasil yang berbeda nyata memiliki tingkat kesembuhan inflamasi,pertumbuhan bulu dan kematian parasit dibanding P0, P2 dan P3. Kesimpulan :unguentum ektrak koral kelimutu sangat efektif digunakan sebagai terapi scabiosis padahewan.
Co-Authors Laksmyn Kadir Muhammad Farid Rizal Olan Rahayu Puji Astuti Nussa Raden Roro Nurul Ramadhanti