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All Journal Jurnal Surya Medika Syntax Literate : Jurnal Ilmiah Indonesia Journal of halal product and research (JHPR) Jurnal Sains dan Kesehatan
Kosasih Kosasih
Universitas Pancasila
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences Veterinary

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Pengaruh Ketersediaan Obat dan Kualitas Pelayanan Farmasi terhadap Kepuasan dan Loyalitas Pasien Rawat Jalan (Studi pada Rumah Sakit Ibu dan Anak PKU Muhammadiyah Cipondoh, Tangerang) Nurmiwiyati Nurmiwiyati; Amelia Oktrivina DS; MGS Aritonang; Kosasih Kosasih
Jurnal Surya Medika (JSM) Vol 6 No 1 (2020): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v6i1.1474

Abstract

Customer satisfaction is the key to creating customer loyalty, as well as in-hospital services. This study will examine aspects of drug availability and quality of service and its effect on the satisfaction and loyalty of outpatients at PKU Muhammadiyah Hospital in Cipondok, Tangerang. This study uses a survey method with a questionnaire as a data collection tool. A quantitative approach was carried out using Structural Equation Modeling (SEM) analysis with LISREL. The study sample was taken from all patients who visited the outpatient unit at PKU Muhammadiyah Hospital in Cipondoh, Tangerang, or their families who came for treatment and bought medicine at PKU Muhammadiyah Hospital in Cipondoh, Tangerang. The results showed Availability of drugs had a significant effect on outpatient satisfaction, The quality of pharmaceutical installation services has a significant effect on outpatient satisfaction, Availability of drugs significantly influences outpatient loyalty, Service quality has no significant effect on outpatient loyalty, and patient satisfaction has a significant effect on outpatient loyalty. The results of statistical tests noted that 86% of patient satisfaction levels were affected by the availability of drugs and the quality of services, and 89% of patient loyalty was influenced by the availability of drugs and quality of service.
Karakterisasi Ekstrak Daun Cantigi (Vaccinium varingiaefolium Miq.) Ana Yulyana; Hendig Winarno; Kosasih Kosasih
Jurnal Sains dan Kesehatan Vol. 1 No. 5 (2016): Jurnal Sains dan Kesehatan
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (407.937 KB) | DOI: 10.25026/jsk.v1i5.50

Abstract

Cantigi (Vaccinium varingiaefolium Miq.) banyak tumbuh di sekitar kawah gunung berapi namun belum banyak informasi yang terkuak. Tujuan penelitian: Melakukan karakterisasi ekstrak daun Cantigi yang diekstraksi secara maserasi menggunakan pelarut n-heksan, etilasetat, dan etanol 95%; penapisan fitokimia ekstrak; uji aktivitas sitotoksik ekstrak; fraksinasi ekstrak dengan kromatografi kolom; uji sitotoksik fraksi; pembuatan profil GC/MS fraksi teraktif. Hasil penelitian: Hasil penapisan fitokimia menunjukkan positif untuk flavonoid, steroid, tannin, dan triterpenoid. Aktivitas sitotoksik pada sel leukemia L1210 (IC50) 12,67; 8,29; dan 10,42 µg/mL. Fraksinasi ekstrak teraktif etilasetat (Kromatografi kolom: Fase diam silika gel 60, fase gerak kloroform:metanol 10:1, 8:1, dan 4:1) diperoleh 4 fraksi. Aktivitas sitotoksik (IC50) Fraksi 1-4 adalah 3,62; 1,69; 2,98; dan 2,96 µg/mL. Karakterisasi fraksi F2 dengan GC/MS menunjukkan 15 senyawa. Simpulan: Aktivitas sitotoksik fraksi ekstrak etilasetat (F2) lebih tinggi dibandingkan non-fraksi ekstrak etilasetat dan ini belum pernah dilaporkan sebelumnya.
Effects of gelatin and glutaraldehyde concentrations on characteristics of Cantigi (Vaccinium varingiaefolium Miq.) extract loaded gelatin nanoparticles as antioxidant Kosasih Kosasih; Wahono Sumaryono; Diky Mudhakir; Agus Supriyono; Yulius Evan Christian; Ruth Debora
Journal of halal product and research (JPHR) Vol. 4 No. 1 (2021): Journal of Halal Product and Research (JHPR)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jhpr.vol.4-issue.1.1-7

Abstract

Cantigi is an endemic plant of sub-alpine area of Mount Tangkuban Parahu in Bandung, Indonesia. Previous study showed ethanol extract of young red leaves had antioxidant activity, however no information on this activity if changed into nanoparticles. The purpose of this study was to determine the effects of gelatin and glutaraldehyde concentrations on the characteristics of Cantigi extract loaded gelatin nanoparticles and to evaluate the antioxidant activity of nanoparticles. Cantigi leaves were extracted by maceration using n-hexane, ethyl acetate, and ethanol 96%. The ethanol extract was dried, made into nanoparticles by varying gelatin (0.1; 0.2; and 0.3 g) and glutaraldehyde (0.1; 0.2; and 0.3 mL) amounts, and conducted at 500 rpm and 40 °C for 3 hours. Nanoparticles were evaluated for particle size, zeta potential, morphology, and antioxidant activity. Nanoparticles with glutaraldehyde amount variation had particle sizes (PS) of 105.9±26.2; 37.1±8.7; and 32.5±7.4 nm; polydispersity indeces (PI) of 0.508; 0.717; and 0.563; zeta potential values (ZPV) of 0.55; 0.89; and 0.78 mV; and antioxidant activities (IC50) of 56.15±0.16; 53.67±0.10; and 51.57±0.39 ppm, respectively. Then, nanoparticles with gelatin amounts variation had PS of 22.5±5.1; 37.1±8.7; and 83.3±21 nm; PI of 0.604; 0.717; 0.326; ZPV of 1.27; 0.89; 0.18 mV; and antioxidant activities of 51.58±0.19; 53.67±0.12; and 55.46±0.04 ppm, respectively. Nanoparticle morphology was spherical. Cantigi leaf extract can be made into gelatin nanoparticles; the smaller the concentration of the polymer used and higher the concentration of the glutaraldehyde, the smaller the resulted particle size and increased antioxidant activity. Antioxidant activities of nanoparticles was lower than those of the extract (IC50 16.84±0.30 ppm).
Penetapan Waktu Standar dan Evaluasi Waktu pada Pekerjaan Kualifikasi, Kalibrasi, Serta Validasi di Bagian Pemastian Mutu PT XYZ Tahun 2018 Irvan Bastian; Wahono Sumaryono; Kosasih Kosasih
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : CV. Ridwan Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (364.278 KB) | DOI: 10.36418/syntax-literate.v7i5.7027

Abstract

Waktu standar merupakan komponen utama dalam menyusun perencanaan kerja. Waktu standar sangat diperlukan pada proses perencanaan agar perhitungan beban kerja dan perkiraan jumlah personil yang diperlukan menjadi lebih akurat. Di PT XYZ yang bergerak di Bidang Manufaktur Farmasi terdapat permasalahan pada Departemen Pemastian Mutu dimana belum ditetapkannya waktu standar untuk 5 jenis pekerjaan yaitu pekerjaan kualifikasi, kalibrasi validasi proses, validasi metode analisis, dan validasi metode pembersihan. Hal ini menyebabkan kesulitan dalam memperkirakan beban kerja serta jumlah tenaga kerja untuk jenis pekerjaan tersebut. Penelitian ini bertujuan menetapkan waktu standar pada pekerjaan kualifikasi, kalibrasi, dan validasi serta melakukan evaluasi waktu kerja pada 5 jenis pekerjaan tersebut. Penentuan waktu standar dilakukan dengan teknik pengamatan tidak langsung berbasis aktivitas, dimana metode yang digunakan adalahwawancara dan FGD. Waktu standar yang dihasilkan digunakan untuk melakukanevaluasi waktu kerjayang prosesnya dilakukan secara retrospektif dari data tahun 2018. Hasil dari penelitian diperoleh waktustandar dan jumlah personil yang ideal untuk jenis pekerjaan kualifikasi, kalibrasi, validasi proses, validasi metode analisis, dan validasi metode pembersihan. Hasil penelitian ini juga menunjukkan pada tahun 2018 di PT XYZ terdapat kelebihan personil untuk pekerjaan validasi proses dan terdapat kekurangan target kerja untuk pekerjaan validasi metode pembersihan dan validasi metode analisis.
Co-Authors Agus Supriyono Ana Yulyana Diky Mudhakir Hendig Winarno Irvan Bastian MGS Aritonang Nurmiwiyati Nurmiwiyati Ruth Debora Siregar, Amelia Oktrivina Wahono Sumaryono Yulius Evan Christian