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All Journal Jurnal Ilmiah Farmasi Jurnal Ilmu dan Teknologi Hasil Ternak Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice)
Achmad Fudholi
Fakultas Farmasi Universitas Gadjah Mada
Chemistry Computer Science & IT Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health Other

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KINERJA INSTALASI FARMASI RUMAH SAKIT X PURWOKERTO DITINJAU DARI PERSPEKTIF PROSES BISNIS INTERNAL BALANCED SCORECARD “AVERAGE DISPENSARY TIME DAN WAKTU PEMBERIAN INFORMASI OBAT Fithria Dyah Ayu; Satibi Satibi; Achmad Fudholi
Jurnal Ilmiah Farmasi Vol. 10 No. 2 (2013): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.vol10.iss2.art2

Abstract

IFRS (Instalasi Farmasi Rumah Sakit) X Purwokerto adalah salah satu rumah sakit milik pemerintah yang bergerak pada pelayanan publik. IFRS X sebagai salah satu organisasi yang memasuki lingkungan industri kesehatan yang kompetitif harus dapat meningkatkan kinerja dan memberikan pelayanan terintegrasi secara lebih efektif, efisien, dan inovatif. Penelitian ini bertujuan untuk mengetahui proses bisnis internal IFRS X berdasarkan perspektif balanced scorecard, meliputi ratarata dispensing time, dan rata-rata waktu pemberian informasi obat. Desain penelitianini adalah cross sectional. Data kuantitatif didapatkan dari lembar observasi pada resep untuk rata-rata dispensing time
OPTIMASI FORMULASI GEL EKSTRAK DAUN TEMBAKAU (Nicotiana tabacum) DENGAN VARIASI KADAR KARBOPOL940 DAN TEA MENGGUNAKAN METODE Simplex Lattice Design (SLD) Titis Rahayu; Achmad Fudholi; Annisa Fitria
Jurnal Ilmiah Farmasi Vol. 12 No. 1 (2016): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

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Abstract

Abstract Antiseptic preparation that is currently developed today is the hand gel (hand sanitizer). The active substance that has antibacterial activity contained in this gel. Several studies have shown that tobacco leaf extract (Nicotiana tabaccum) has antibacterial activity, so that preparations can be developed by adding tobacco extracts as active ingredient. Formula optimization performed by the method simplex lattice design (SLD) uses 2 components such as Carbopol940 and TEA, with a variety of amount. Viscosity, pH, dispersive power and adhesion of gel formulation is used as a parameter optimization. Based on the equation simplex lattice design, contour plot made to determine the optimum formula. Carbopol940 and Trietanilamin (TEA) with a variety of different amount will affect the physical properties of the gel. The optimum formula obtained by the prediction program Design Expert is the Formula I which have high levels of Carbopol940 0.4 grams and 0.9 grams of TEA. Carbopol940 is the most dominant factor that increases the viscosity and stickiness. TEA is the most dominant factor in raising the pH and the scatter. Keyword: Gel, Carbopol 940, TEA,  Nicotiana tabacum, Simplex Lattice Design (SLD) Intisari Salah satu sediaan antiseptik yang saat ini banyak dikembangkan adalah gel pembersih tangan (hand sanitizer) dengan kandungan zat aktif yang bersifat antibakteri. Beberapa penelitian membuktikan bahwa ekstrak daun tembakau (Nicotiana tabaccum) menhasilkan aktivitas antibakteri, sehingga sediaan hand sanitizer dapat dikembangkan dengan menambahkan ekstrak tembakau sebagai zat aktifnya. Optimasi formula dilakukan dengan metode simplex lattice design (SLD) menggunakan 2 komponen yaitu Karbopol 940 dan TEA, dengan berbagai variasi kadar. Viskositas, pH, daya sebar dan daya lekat sediaan gel digunakan sebagai parameter optimasi. Berdasarkan persamaan simplex lattice design, dibuat contour plot untuk menentukan formula optimum. Karbopol dan Trietanilamin (TEA) dengan variasi kadar yang berbeda akan mempengaruhi sifat fisik gel yang dihasilkan. Formula optimum yang diperoleh berdasarkan prediksi program Design Expert adalah pada Formula I yang memiliki kadar Karbopol 940 0,4 gram dan TEA 0,9 gram. Karbopol 940 merupakan faktor yang paling dominan meningkatkan viskositas dan daya lekat TEA merupakan faktor yang paling dominan menaikkan pH dan daya sebar. Kata kunci: Gel, Karbopol 940, TEA,  Nicotiana tabacum, Simplex Lattice Design (SLD)
MENGGUNAKAN MATRIKS HPMC K100M DAN XANTHAN GUM DENGAN METODE EFFERVESCENT OPTIMASI FORMULA TABLET FLOATINGNIFEDIPIN Nurniswati Nurniswati; Achmad Fudholi; Abdul Rohman
Media Farmasi: Jurnal Ilmu Farmasi Vol 11, No 1: Maret 2014
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3116.963 KB) | DOI: 10.12928/mf.v11i1.1394

Abstract

Nifedipin  (NIF)  adalah  obat  kardiovaskular  dengan  frekuensi  penggunaan berulang  kali  dalam  sehari.  Ketika  diberikan  secara  oral  dalam  bentuk  sediaan padat konvensional, absorpsi NIF rendah. Sehingga perlu dikembangkan sediaan lepas lambat  yang dapat dipertahankan lama dalam lambung. Dengan sistem ini NIF  bisa  diberikan  1x1  hari,  yang  akan  menjamin  kepatuhan  pasien  dan pencapaian  target  terapi.Penelitian  bertujuan  untukmengetahui  pengaruh  kombinasi HPMC K100M,xanthan gum dan komponen effervescent terhadap sifat fisik  massa  tablet,  sifat  fisik  tabletdan  pelepasan  zat  aktifnya,  serta  berapa komposisi  tiap faktor  untuk  menghasilkan  formula  optimum. Rancangan penelitian  yang  digunakan  adalah  rancangan  faktorial  23 sehingga  didapatkan  8 formula. Parameter optimasi yang digunakan adalah floating lag time(FLT),  daya serap,  C 360 dan  DE 360.  Penentuan  profil  disolusi  berdasarkan  metode  linierisasi kurva.Berdasarkanpendekatan  nilai  desirability diperoleh  formula  optimum dengan komposisi HPMC K100M 81,0 mg, xanthan gum 48,2 mg dan komponen effervescent 60,0  mg. Formula optimum memberikan hasil pengujian  floating lag time,  daya  serap  dan  C360 yang  tidak  berbeda  signifikan  terhadap  hasil  prediksi softwareyang digunakan (Design Expert7.1.3). Profil pelepasan formula optimum mengikuti kinetika orde 1.
Amino Acid Profile, Group of Functional and Molecular Weight Distribution of Goat Skin Gelatin That Produced Through Acid Process Muhammad Irfan Said; Suharjono Triatmojo; Yuny Erwanto; Achmad Fudholi
Jurnal Ilmu dan Teknologi Hasil Ternak (JITEK) Vol. 6 No. 1 (2011)
Publisher : Faculty of Animal Science Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (592.228 KB)

Abstract

Gelatin is a product of hydrolysis of collagen protein from animals that are partially processed.  Gelatin used in food and non food industries.  Gelatin is produced when many import of raw skins and bones of pigs and cows.  Goat skins potential as a raw material substitution that still doubt its halal. Process production of gelatin determine the properties of gelatin. The objectives of this research were to determine amino acid profile, group of functional and molecular weight distribution of gelatin made from goat skins which was produced through a process of acid. The skin of male Bligon goat, 1.5 to 2.5 year old was used as raw materials. Process production of gelatin was using acid type acetic acid (CH3COOH 0.5 M) (v/v) as curing material. The experimental design applied in this study and commercial gelatin was used as control. The results showed that gelatin produced from goat skin through the process of acid had properties identical with commercial gelatin. It can be concluded that the gelatin has the potential substitute product of commercial gelatin. Keywords: collagen, gelatin, goat skin, curing, acid process
THERAPY COST ANALYSIS AND EFFECTIVENESS OF TREATMENT OF OUTPATIENT WITH TYPE 2 DIABETES MELLITUS AT RSUD SLEMAN YOGYAKARTA Pratiwi Dinaryanti; Achmad Fudholi; Tri Murti Andayani
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 2, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.54

Abstract

Diabetes is a chronic disease that can significantly increase a person›s risk of having complications. These complications not only cause the inability of the body that will affect the quality of life, but also need big cost. This research was conducted to analyze the costs and effectiveness of therapies of outpatient with type 2 diabetes mellitus. A crosssectional observational method was performed on 100 patient who were admitted to the Department of Endocrinology of the Sleman Hospital between December 2010 to January 2011. Data were taken in 2 ways: concurrent and retrospective, with accidental sampling technique. The subject of this research were outpatient with type 2 diabetes mellitus at RSUD Sleman Yogyakarta, who have used the antidiabetic therapy for at least three months of therapy before the quality of life measurement. The costs that are measured are direct medical costs, antidiabetic costs, complication costs, laboratory examination costs, and administration costs. The effectiveness of treatment parameters was measured based on the percentage of patients with fasting blood glucose level (GDP) and post-prandial blood glucose (GDPP) which reached the target in the third month of therapy, and achievement of the quality of life research subjects. The Lowest total cost of therapy was the use of glibenclamide, it was 49.730,00, the highest total cost of therapy was the use of insulin, it was Rp. 411.045,50. T test results with 95% confidence level indicates that the patient characteristics and medication adherence complications affect the patients quality of life, whereas non-pharmacological therapy (exercise and diet) did not significantly influence the patients quality of life. The results of measurements of quality of life showed metformin achieved the best quality of life than the other antidiabetic, i.e. 72.53. Based on the effectiveness of the three parameters (measurement of quality of life and levels of GDP and GDPP) note that metformin therapy tend to be more effective compared with other antidiabetic therapies.Key words: Diabetes mellitus type 2, cost analysis, effectiveness, antidiabetic, RSUD Sleman Yogyakarta.
ANALYSIS OF PHARMACIST ATTITUDE TOWARD GOVERNMENT REGULATION NO. 51/2009 CONCERNING PHARMACY PRACTICE (CASE STUDY IN PALEMBANG PHARMACIES) Rastria Meilanda; Achmad Fudholi; Sumarni Sumarni
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 2, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.61

Abstract

Pharmacist holds authority on professionalism in performing pharmacy work. That authority provides definite legitimacy for pharmacist as a profession in performing her/his function and roles within health domain to achieve pharmacy service standard, particularly in drugs services at pharmacy-store listed in Government Regulation No. 51/2009 concerning pharmacy practice. These function and rule should be indicated within attitude and behave as pharmacist. Attitude and behavior strongly determined the pharmacist’ responsibility and service. The presents research was expected provide a foundation for pharmacist attitude and behavior in implementing PP No. 51/2009. It gives an overview of the readiness of pharmacists in the pharmacy, especially Palembang city  in implementing these regulations so that the objective standard of pharmaceutical care can be achieved. This research is descriptive research, data were gained throught questioner. Pharmacist attitude were classified into three dimensions which named as cognitive, affective and cognation dimensions. Samples were selected by random sampling method by giving questioner titled pharmacist attitude in facing PP No. 51/2009. Collected data were followed by validation and reliability test, then been analyzed to obtain research outcome. Research outcome reveals that most pharmacists in Palembang City has acknowledged and well-understand over PP No.51/2009. They also perceived content and, thus, raise positive attitude and inclined to behave according to the regulation. However, pharmacist who disagree with PP No. 51/2009 since perceives difficult to implement it do not sentenced any sanction both from organization and government, generally this caused by limited knowledge gain by pharmacist.Keywords: Pharmacist, Attitude, PP No. 51/2009
INTELLECTUAL PROPERTY RIGHTS (IPRs) MANAGEMENT AS A STRATEGY OF CORPORATE ADVANTAGE: CASE STUDY PT CIPTA SARANA KENAYU LESTARI Septilina Melati Sirait; Achmad Fudholi; Gede Bayu Suparta
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 3, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.96

Abstract

Every company needs a knowledge-based management including knowledge in managing intellectual property in order to make innovation continuously to anticipate dynamic change of environment. The purpose of this research was to assess the management of innovation and intellectual property management to be used as the strategy of corporate advantage on PT Cipta Sarana Kenayu Lestari (PT CSKL). This research was a qualitative study producing the descriptive data in a form of the written or spoken words from the respondents. The respondents were the top management of PT CSKL that were selected by purposive sampling. The method to collect the data were interview, observation, documentation and literature methods. Then the data were systematically analyzed by arranging the data and derive a conclusion. The result showed that PT CSKL has managed many innovations both of product and process. PT CSKL was aware of the importance of innovation and IPR protection into business process by registering to the Director General of Intelectual Property Rights (IPRs). However, from the existing regime, PT CSKL only managed brand and trade secret. This was because of limited cost and facilities classified as PT CSKL is small and medium enterprises. Some intellectual property which were not registered were logo’s company, formula of honey lipstick, website, brochure and packaging design. IPR protected by law is used as a strategy advantage of PT CSKL in doing business development strategy. This strategy starts from the management of innovation in family firms into strategic corporate level towards good corporate governance and cooperation strategic alliance, followed by a strategic business level towards to Porter’s focus strategic and competitive strategic as industrial fragmented and strategic level functional in production, marketing, finance and research and development and quality control.Keywords: innovation, intellectual property rights, strategic advantage, PT Cipta Sarana Kenayu Lestari.
EVALUATION OF DRUGS SUPPLY MANAGEMENT IN HEALTH DEPARTMENT OF KABUPATEN CILACAP DISTRICT IN 2008, 2009 AND 2010 Tiekha Kencanasari; Achmad Fudholi; Satibi Satibi
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 2, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.69

Abstract

Drugs supply management aims to control the drugs supply and make sure that the drugs in good condition, fairly distributed, and fulfill the types and quantity of the drugs needed by health service. Health department of Cilacap District faced many obstacles in drugs supply management during 2008-2010. Therefore, evaluation of drugs supply management in health department of Kabupaten Cilacap during 2008-2010 certainly needed to make the better drugs supply. The research conducted with observational method using descriptive monitoring. Data were collected retrospectively using data of planning, drugs supply and storage, and drugs consumption in health department of Cilacap District. Indicators that used in the research were indicators that determined by health Department of Indonesia in 2006. Primary data were gathered through interview with 3 groups: policy group, drugs supply group, and drugs consumption group or drugs management. Values of drugs management indicators –based on pedoman supervisi dan evaluasi obat publik dan perbekalan kesehatan were gathered through evaluation. The evaluation results show that in 2008, 2009, 2010, the indicators were not fit with the standard indicator, such as: indicator of drugs’ planning accuracy (147%, 108% and 145%), drugs charge per person in Cilacap District (Rp.1.342, Rp.2.000, Rp.4.615) accuracy level of financing the drugs supply (94,60%, 95,04%, 98,30%), and percentage of financing drugs supply (24,8%, 14,8%, 49%). Indicators that fit with the standard indicators were such as: Level of drugs supply (16, 5, and 7 months), accuracy level of drugs item with DOEN 52,4% during 2008-2010, generic drugs supply (89,6%, 79,1%, 88,2%), accuracy level of drugs distribution 100% during 2008-2010, accuracy level of LPLPO delivery time, drugs supply is fit with the drugs demand (109%, 160%, 167%), and drugs charge per visit per prescription (Rp.7.512, Rp. 8.180, Rp. 7.536). Keywords: Drugs Supply Management, Evaluation, Indicators, Health Department of Kabupaten Cilacap
Co-Authors Abdul Rohman Annisa Fitria Fithria Dyah Ayu Gede Bayu Suparta Muhammad Irfan Said Nurniswati Nurniswati Pratiwi Dinaryanti Rastria Meilanda Satibi Satibi Septilina Melati Sirait Suharjono Triatmojo Sumarni Sumarni Tiekha Kencanasari Titis Rahayu Tri Murti Andayani Yuny Erwanto