Article Per Year (5 Year)
p-Index From 2019 - 2024
0.444
P-Index
This Author published in this journals
All Journal Jurnal Wiyata : Penelitian Sains dan Kesehatan Jurnal Pharma Bhakta
KRISNA KHARISMA PERTIWI
INSTITUT ILMU KESEHATAN BHAKTI WIYATA
Health Professions Medicine & Pharmacology Public Health Social Sciences Other

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
ANALGETIC ASSAY OF TREMBESI LEAVES (Samanea saman (Jacq.) Merr.) KRISNA KHARISMA PERTIWI; DWI WAHYUNI; ROSA J HESTURINI; AGUSTINA DWI LESTARI
Jurnal Wiyata Penelitian Sains dan Kesehatan Vol 7, No 2 (2020)
Publisher : LP2M IIK (Lembaga Penelitian dan Pengabdian Masyarakat Institut Ilmu Kesehatan) Bhakti Wiy

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Trembesi (Samanea saman (Jacq.) Merr.) is a plant of the genus Samanea spread in tropical areainclude Indonesia. This plant have some chemical ingredients such as flavonoids, alkaloids, tannins, saponins,  and steroids or triterpenoids. Objective: To know the analgesic activity and the effective dose of ethanol extract of leaves of trembesi  in white male mice (Mus musculus L.). Method: This research is experimental with Post-Test Only Control Group Design techniques. Analgesic activity test was performed by chemical induction method using acetic acid in vivo with a negative control treatment (CMC-Na 0,5%), a positive control (aspirin 500mg), dose of ethanol extract of trembesi 150, 300 and 600 mg/kgBB. Data were analyzed with Hendersoth and Forsaith equation to determine the amount of stretching by mice. Analysis by One Way ANOVA test and LSD test. Results: The results showed the analgesic power percent ethanol extract of trembesi leaves are respectively 16.6%, 45.8% and 69.6%. Conclusions: The dose of ethanol extract of trembesi leaves have analgesic activity with the most effective dose is 600 mg/kgBB is equivalent to 500mg of aspirin (p=0.560).
SKRINING FITOKIMIA DAN KROMATOGRAFI LAPIS TIPIS EKSTRAK DAUN BELUNTAS (Pluchea indica L.) asih imulda hari purwani; Fita Sari; Krisna Kharisma Pertiwi; Tri Puji Lestari
JURNAL PHARMA BHAKTA Vol 4 No 1 (2024): Mei 2024
Publisher : FAKULTAS FARMASI, INSTITUT ILMU KESEHATAN BHAKTI WIYATA

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Latar belakang: Daun beluntas mempunyai senyawa metabolit sekunder yaitu flavonoid, tanin, sedangkan akarnya terdapat senyawa flavonoid. Skrining fitokimia termasuk uji kualitatif pada ekstrak daun beluntas dan KLT yaitu untuk memisahkan senyawa berdasarkan tingkat kepolaranya yakni fase diam dan fase gerak. Tujuan: Mengetahui hasil skrining fitokimia dari ekstrak daun beluntas, serta pada KLT dapat mengetahui hasil Kromatografi Lapis Tipis (KLT) dari ekstrak daun beluntas. Metode: Daun beluntas dilakukan proses ekstraksi kemudian skrining fitokimia yaitu uji flavonoid, tanin dan saponin. Ekstrak daun beluntas dilakukan uji KLT fase gerak toluen : aseton : asam formiat (6:6:1 v/v) dengan fase diam silika gel GF 254. Hasil: Ekstrak daun beluntas terdapat senyawa metabolit yaitu flavonoid, saponin dan tanin. KLT ekstrak daun beluntas positif flavonoid dengan terdapat noda warna kuning kecoklatan dalam UV 366 nm dengan Rf 0,57 cm. Simpulan: Ekstrak daun beluntas terdapat kandungan senyawa flavonoid, saponin dan tanin dengan Rf 0,57 cm
Co-Authors AGUSTINA DWI LESTARI Asih imulda Hari Purwani DWI WAHYUNI Fita Sari ROSA J HESTURINI Tri Puji Lestari